5NB9,1DVO


Conserved Protein Domain Family
ProQ

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pfam04352: ProQ 
ProQ/FINO family
This family includes ProQ, which is required for full activation of the osmoprotectant transporter, ProP, in Escherichia coli. This family includes several bacterial fertility inhibition (FINO) proteins. The conjugative transfer of F-like plasmids is repressed by FinO, an RNA binding protein. FinO interacts with the F-plasmid encoded traJ mRNA and its antisense RNA, FinP, stabilizing FinP against endonucleolytic degradation and facilitating sense-antisense RNA recognition. ProQ operates as an RNA-chaperone, binding RNA and bringing about both RNA strand-exchange and RNA duplexing. This suggests that in fact it does not regulate ProP transcription but rather regulates ProP translation through activity as an RNA-binding protein.
Statistics
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PSSM-Id: 398170
Aligned: 58 rows
Threshold Bit Score: 70.71
Threshold Setting Gi: 500738203
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5NB9_A           24 SKEVIAFLAERFPhCFSAEgeARPLKIGIFQDLVdRvAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCG 103
jgi:Daci_0307    91 QHPLLAQLAQWHPnLFGEQ--PLPLKRGIFEDLL-A-AHPEAIDRDQLKLALSQHTRSSRYLTVVASGQARHDLQGQSVE 166 Delftia acid...
CAS:CtCNB1_0199  73 QHPLLEQLAQWHPaLFGEQ--LLPFKRGIFEDLL-A-AHPE-LDKDALKSALQQHTRSGRYLAAMASGQQRHDLSGQPVE 147 Comamonas th...
Q21RU1           31 VQPVLEKLFELYPhLFGAE--FLPLKLGIFQELL-A-LHPEQFQRDSLKLALGLHTRSTRYLQSVAAGKPRHDLQGAAVE 106 Rhodoferax f...
Q12EQ6           43 VHPALEKLFELYPkMFGAQ--FLPLKLGVFQELL-A-QHPDAFNRDELKVALGLHARSTRYLESVAAGLPRHDLQGEPVE 118 Polaromonas ...
BAL93370         46 pAECAARLAELFPaLFAp--pPKPLKLRIQADIQ-A-RAPGIFTRRTLSVFLHRYTTSNAYLSALVKAEQRFDLDGQPAG 121 Rubrivivax g...
EHR68935         70 paACAQALAQHFPaMFGADqpPRPLKLRIQADIQ-Q-RAPGVFSRKAMGLFFSRHTTTTAYLKALLASATRFDLDGQPAG 147 Burkholderia...
WP_015767788     14 ARQLLKQLQEQFP-VFRD---CLPLAIGIDKQLL---ARLPDLNRKELRIALGIHTHSLRYLKTTEKATARVDLDGNPAG 86  Candidatus A...
nioo:CFU_0163    19 ARVLLKELQEKFA-VFRD---YQPLAIGIDKQLI---ALTPELNRKTLRIALGMHTNSLRYLKGMEKATHRFDLEGNSTD 91  Collimonas f...
CAL63045         13 ARILLKELQEKFP-VFGD---FLPLAIGIDKQLI---ALTPDVSRKSLRTALGIHTNSLRYLKGMEKATIRFNLDGSHAD 85  Herminiimona...
5NB9_A          104 ELDEQHVEHARKQLEEAKARVQAQRAE 130
jgi:Daci_0307   167 AMAPEHVHHALIEVFRRRQHRSPEDla 193 Delftia acidovorans SPH-1
CAS:CtCNB1_0199 148 ATLPEHVHHALIEVFRRRQQRTQEDLt 174 Comamonas thiooxydans
Q21RU1          107 AVAPEHVHFALLELFRRRQGRTQADLr 133 Rhodoferax ferrireducens T118
Q12EQ6          119 PVAPEHVHHAILEVFRRRQARSREDLR 145 Polaromonas sp. JS666
BAL93370        122 ELSAEHRELAAAEIARRRGVHEQRRAA 148 Rubrivivax gelatinosus IL144
EHR68935        148 DIADEHRQAAQEELNRRRDLVQQRRAA 174 Burkholderiales bacterium JOSHI_001
WP_015767788     87 EIMATHRTHAAELVKDRLKKQAEQRRT 113 Candidatus Accumulibacter phosphatis
nioo:CFU_0163    92 EVTEVHRTHATETLRERFKKNAEQRKA 118 Collimonas fungivorans Ter331
CAL63045         86 EVTDVHRTHATTTLKERFKKNAEQRKA 112 Herminiimonas arsenicoxydans
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