1KMI


Conserved Protein Domain Family
CheZ

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pfam04344: CheZ 
Chemotaxis phosphatase, CheZ
This family represents the bacterial chemotaxis phosphatase, CheZ. This protein forms a dimer characterized by a long four-helix bundle, composed of two helices from each monomer. CheZ dephosphorylates CheY in a reaction that is essential to maintain a continuous chemotactic response to environmental changes. It is thought that CheZ's conserved residue Gln 147 orientates a water molecule for nucleophilic attack at the CheY active site.
Statistics
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PSSM-Id: 398165
Aligned: 101 rows
Threshold Bit Score: 189.255
Threshold Setting Gi: 218764493
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KMI_Z             16 DIIARIGSLTRMLRDSLRELG--LD-QAIAEAAEAIPDARDRLYYVVQMTAQAAERALNSV-------EASQPHQDQMEK 85 
ACL06959          307 gLFGEIGQMARALHESLREFSntLDpEMKGLVEEKLPDSSLRLEHIIELTENAASTTMDLTeviqernEKSMALMDKLKS 386 Desulfatib...
jgi:Hneap_0719     42 PVFEQVGQMTREVHEALMAFA--LDeRLDRMAEAEMPDARDRLRYVISLTEQAATRTLALV-------EEAFPLTERLVE 112 Halothioba...
WP_022775001        9 EAYTRLGAIVREMHEALTLLG--SN--QLNSIVQEIPNARDRLTYVGKMTEDAANKVLGLV-------EKAKPDCDHLAT 77  Candidatus...
jgi:Mpe_A2875      20 EVFQQLGAITRQLHDTLAQLG--VT-PKLQQAAEGLPDARSRLNYIAEKTAAAANKVLNSV-------DQAKMEHTRIAA 89  Methylibiu...
UCNUF:Cenrod_1300  22 DVHLRLGSLTRQLHDSLNGLG--LT-DKVRTWAGELPDAKSRLSYIARLTGEAAEKVLNSV-------DQAKVHHDHIAE 91  Candidatus...
Q21S48             17 DIHQSIGVLTRQLHDALNGLG--LT-DKVKGWAGEIPDAKSRLSYIARLTGEAAEKVLNRV-------DMAKAQHDHIAS 86  Rhodoferax...
WP_003077948        9 NVHYKIGVLTRQLHNSLNELG--YA-DRLRGSAGELPDAQSRLSYIARLTGEAANKVLGQV-------EVTQNRQDALAE 78  Comamonas ...
jgi:Daci_0601       9 SVHYKVGVLTRQLHDSLNELG--YA-DRLRGSMGELPDAQSRLSYIARLTGEAAEKVLNRV-------ELAKVQQDRLAE 78  Delftia ac...
WP_011806905       15 DVHHKIGQLTRQLHSALNELG--YA-DQLRGTMGELPDAQSRLSYIARLTGEAAEKVLGRV-------EQAKSLHDHVAS 84  Acidovorax...
1KMI_Z             86 SAKALTQRWDDWFADP-ID---LAD---------------ARELVT-DTRQFLADVPAHTSFTNAQLLKIMMAQDFQDLT 145
ACL06959          387 SSSDVEVLMASLDKLMdLAtenKDQpsaenipimhgllrmAREKVQ-ACGAATDSIMESTTATNKDLVDIFTAQDYQDLT 465 Desulfatib...
jgi:Hneap_0719    113 RSERLHQQLAQVAEKE-AD---NRR---------------LVEVIH-TITDYLDSVLGSGNALKSRLTEVMMAQEFQDLS 172 Halothioba...
WP_022775001       78 HGSELSQSLARMASAEdFS---VDR---------------ARALLM-VCGKFADRTARFAQDQAETLSDIMMAQDFQDLS 138 Candidatus...
jgi:Mpe_A2875      90 ETRRIAAA---------IV---ADP---------------VKAVASgSVMNFVSDVEAATARIDADLTDIMMAQDFHDLT 142 Methylibiu...
UCNUF:Cenrod_1300  92 ETRRIGAL---------LA---ADP---------------AAAVAQgHVAQFVAEVDRTSREIDQNLTDIMMAQDFHDLT 144 Candidatus...
Q21S48             87 ETRRIGTL---------IV---KDP---------------VGAVAKgHVMNFLTDVEQSTQQIDQHLTEIMMAQDFHDLT 139 Rhodoferax...
WP_003077948       79 RTRAMRAE---------LI---KDP---------------VAAVAKgRVMNYLQEVEEGTEQTNSHLTEIMMAQDFHDLT 131 Comamonas ...
jgi:Daci_0601      79 RVRAMRAQ---------MV---EDP---------------VAAVAKgRVMNFLEEVEQGTQQADEHLTEIMMSQDFHDLT 131 Delftia ac...
WP_011806905       85 ETRRVVTS---------LV---ADP---------------VAAVAKgEIYNFLTDVERATQEADSHLTEIMMAQDFHDLT 137 Acidovorax...
1KMI_Z            146 GQVIKRMMDVIQEIERQLLMVLLENIPEQES--RPKr-----------------eNQSLLNGPqv-dtSKA--GVVASQD 203
ACL06959          466 GQVIQKIITLIKDLESKLLNLVTKFGVkvskd-------------------ktgeQQEELYGPs----HAQrdDAVHSQD 522 Desulfatib...
jgi:Hneap_0719    173 GQLLMRVINLLEQLESKMVSLLHLTSPEITSgdRQKkggd------------sseDLQKGTGPalpkeSS---DVVKSQD 237 Halothioba...
WP_022775001      139 GQVIKKVVDIINRTEVQLVQLLLDSSP--------GastaespdpsatqtatmnvNDHRLEGPqt-------aDDALKQS 203 Candidatus...
jgi:Mpe_A2875     143 GQVVAKVVSLASDLEDSLVKLLVQAAPpeqa--------------------qkvvENTILNGPvvnpeGRT--DVVQNQG 200 Methylibiu...
UCNUF:Cenrod_1300 145 GQVITRVVSLAANIEEQLVQLLIVTAPpeaqgip--------------aqllaksTEHALDGPvvnaaNRT--DVVQGQS 208 Candidatus...
Q21S48            140 GQVIAKVVTLVANVEEQLVQLLIQTAPadavvkap-------------thvaaagLKPVLEGPvvcpeGNP--DVVTGQS 204 Rhodoferax...
WP_003077948      132 GQVIARVVALAADLESQLLQLLIQTSPdtaqmpa---------------lapveaAQPKLAGPvvdpeNTT--DVVTSQS 194 Comamonas ...
jgi:Daci_0601     132 GQVIARVVSLAADLEDQLVQLLIQTSPnpqqta----------------leplekPKEHLAGPvvdpeKTP--DVVTSQS 193 Delftia ac...
WP_011806905      138 GQVIARVVNLAATIEQQLVQLLIQTAPpqaqpp-----------------iapepRRDQLQGPvvnpeSAP--DVVTSQS 198 Acidovorax...
1KMI_Z            204 QVDDLLDSLGF 214
ACL06959          523 EVDALLKEFGF 533 Desulfatibacillum aliphaticivorans
jgi:Hneap_0719    238 DVDDLLASLGF 248 Halothiobacillus neapolitanus c2
WP_022775001      204 DVDDLLASLGF 214 Candidatus Symbiobacter mobilis
jgi:Mpe_A2875     201 EVDDLLASLGF 211 Methylibium petroleiphilum PM1
UCNUF:Cenrod_1300 209 EVDDLLASLGF 219 Candidatus Symbiobacter mobilis CR
Q21S48            205 EVDDLLASLGF 215 Rhodoferax ferrireducens T118
WP_003077948      195 QVDDLLASLGF 205 Comamonas testosteroni
jgi:Daci_0601     194 QVDDLLASLGF 204 Delftia acidovorans SPH-1
WP_011806905      199 QVDDLLASLGF 209 Acidovorax sp. JS42
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