Conserved Protein Domain Family
VirB8

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pfam04335: VirB8 
VirB8 protein
VirB8 is a bacterial virulence protein with cytoplasmic, transmembrane, and periplasmic regions. It is thought that it is a primary constituent of a DNA transporter. The periplasmic region interacts with VirB9, VirB10, and itself. This family also includes the conjugal transfer protein family TrbF, a family of proteins known to be involved in conjugal transfer. The TrbF protein is thought to compose part of the pilus required for transfer. This domain has a similar fold to the NTF2 protein.
Statistics
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PSSM-Id: 398158
Aligned: 51 rows
Threshold Bit Score: 102.804
Threshold Setting Gi: 75493888
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Ajs_4270   46 AARRTWNDHVGGVVSQRQTWQVIGILSLLIALAGVgGVIHIGSQSKFIP-YVVE-VDKL-GQTVAAGPVqAAG-KA--DP 119 Acidovorax sp....
Q2YJ78         25 eALNWEAAHVRLVEKSERRAWKIAGAFGTITVLLGiGIAGMLPLKQHVP-YLVR-VNAQtGAPDILTSL-DEK-SVsyDT 100 Brucella abort...
Q7VSX6         20 aAVDWEASRLYRLAQSERRAWTVAWAALAVTALSLiAIATMLPLKTTIP-YLIE-VEKSsGAASVVTQF-EPR-DFtpDT 95  Bordetella per...
WP_011950749   19 HARSWDQDRQRKSLRSERIAWVVAGLGLLAATAEGfALAGLAPLKTVMP-YIIR-VNQTtGAVDVQTTL-TQK-PMryDE 94  Sphingomonas w...
Q9PHJ3         16 EARTWETDKVHDLLKSRKTAWWVAGASAAIAFVAVlAVAALTPLKTTEP-YVIR-VNNNtGAVDVVKAM-KEG-KTnyDE 91  Xylella fastid...
Q7D3R5         13 KARRFDQDRMIQVERSKRIAWSIAIVSGIVAAVAVfAVACLTPLKTVEP-FVVR-VDNStGIVDVVSAL-TST-AGtyDE 88  Agrobacterium ...
jgi:Acry_3526  23 DVESFQATEKRTARRWGRVGWVVAGVSLAVNVTLAgAIVMILPLEKLVPaFIIVkSDGTtSTTMNFNSL-----PSdeKA 97  Acidiphilium c...
P17798         21 evEAFQTARAKSARRLSKVIAAVATIAVLGNVAQAfTIATMVPLIRLVPvY-LW-IRPD-GTVDSEVSV-SRL-PAtqEE 95  Agrobacterium ...
Q1QFH3         19 DGATWERDIARRNRNSRALAWIVAAVMTIVAVGALgTLALLVPLKTYEP-YMVV-VDKTtGFVEVKRPM-AEG-PLtqDE 94  Nitrobacter ha...
Q11N51         15 QGDIWEQEIIKRAKRSARVAWFFSIVFAGIALLSLlGVVLMLPLKSFEP-YIVT-VDRTtGYIEVKSGL-TRPaNLteQQ 91  Chelativorans ...
jgi:Ajs_4270  120 RVIHAAVADWMScARMVSPdvamqRKCVFKAYSMlaPNDPATPKMNEWL-----NGTpdsSPFKRAEKEM-VSVEIKTVI 193 Acidovorax sp....
Q2YJ78        101 VMDKYWLSQYVI-ARETYDwy-tlQKDYETVGML--SSPSEGQSYASQFq----Gd---kALDKQYGSNVrTSVTIVSIV 169 Brucella abort...
Q7VSX6         96 LMNQYWLTRYVA-ARERYDwh-tiQHDYDYVRLL--SAPAVRHDYETSY-----Eap--dAPDRKYGAGTtLAVKILSAI 164 Bordetella per...
WP_011950749   95 AVTKFFLAQYVR-ARESWLpa-aaEENFRAVTIL--SEPGEQQRWGRFF-----NSNnaaSPQVVWGKGAvVQARVRNIA 165 Sphingomonas w...
Q9PHJ3         92 AINKYFVQWYVR-YRESYSre-laEDYYSYVGIF--SNDVEQQKYSAAF-----NPKnpqSPLNIYGTYAkVKIDIQSTS 162 Xylella fastid...
Q7D3R5         89 AVTKYFAAKYVR-AREGYVws-eaQENFRTIALL--STQAEQTRFAALY-----RGSnpqSPQNTYGRGAtARIDIASIS 159 Agrobacterium ...
jgi:Acry_3526  98 AMTRAAIWQYVR-ARESYDfa-daQYRYDVASLM--SNPTVQGTYQSWFldkgpGs---tSPQVTVGKKGqISVAMVSMS 170 Acidiphilium c...
P17798         96 AVVNASLWEYVR-LRESYDad-taQYAYDLVSNF--SAPMVRQNYQQFF-----NYPnptSPQVILGKHGrLEVEHIASN 166 Agrobacterium ...
Q1QFH3         95 AVTTFNVVRYIK-ARETYDpk-alKDNFDLAQLL--ASGDASRELTEIY-----SPAnpsNPVKVFGSNTvIAVNIKSVT 165 Nitrobacter ha...
Q11N51         92 AVTQANVVRYIR-AREGYDpy-aiEENFGIAALL--STDEAARELQALY-----SAAnaqNPAKVYGRLKrVLVEIKSVT 162 Chelativorans ...
jgi:Ajs_4270  194 PQTPDTWQVEWVETTRDRQGTL-KGQPvTWRALVTTyiaEVTPNT-TDEQLRNNPLSIYVRDYSWSR 258 Acidovorax sp. JS42
Q2YJ78        170 PNGKGIGTVRFAKTTKRTNETGdGETT-HWIATIGYqyvN-PSLM-SESARLTNPLGFNVTSYRVDP 233 Brucella abortus 2308
Q7VSX6        165 DHGKGVGTVRFVRTRRDADGQGaAESS-IWVATVAFaydQ-PRAL-TQAQRWLNPLGFAVTSYRVDA 228 Bordetella pertussis Tohama I
WP_011950749  166 FINDRVANVRFTRTVQTDTDTQ---SS-DWIATVTFry--tNAPM-AEGDRYRNPLGFQVENYRADP 225 Sphingomonas wittichii
Q9PHJ3        163 FIHSNVALVRYTKKVERGLDQP--QIT-HWLATITFky--lNTPM-KEKDRGINPLGFQVSEYRNDP 223 Xylella fastidiosa
Q7D3R5        160 LINQNVVSVRYMRTITRGEE---VRTT-HWVASITYsy--aNAPM-SSTDRLVNPLGFVVSEYRADP 219 Agrobacterium fabrum str. C58
jgi:Acry_3526 171 MVRPNVALVRFRRTVTMYGSVP--QTS-TWTATVGFe----NVATlPVSARLADPSGLIVTNYQAQK 230 Acidiphilium cryptum JF-5
P17798        167 DVTPGVQQIRYKRTLI-VDGKM-PMAS-TWTATVRYe---KVTSL-PGRLRLTNPGGLVVTSYQTSE 226 Agrobacterium fabrum str. C58
Q1QFH3        166 FPNNRTALARFSTEEKSSTNII---TR-NWVSLVRFry--tSAPM-RNEWRFDNPLGFQVLEYRRDQ 225 Nitrobacter hamburgensis X14
Q11N51        163 FPNTSTAIVRFSTNERSDTESI---VR-HWISVVRFry--tDTPM-RNEWRFENPLGFQVYSYRRDQ 222 Chelativorans sp. BNC1
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