Conserved Protein Domain Family
Fer2_BFD
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pfam04324: Fer2_BFD 
BFD-like [2Fe-2S] binding domain
The two Fe ions are each coordinated by two conserved cysteine residues. This domain occurs alone in small proteins such as Bacterioferritin-associated ferredoxin (BFD). The function of BFD is not known, but it may may be a general redox and/or regulatory component involved in the iron storage or mobilisation functions of bacterioferritin in bacteria. This domain is also found in nitrate reductase proteins in association with Nitrite and sulphite reductase 4Fe-4S domain (pfam01077), Nitrite/Sulfite reductase ferredoxin-like half domain (pfam03460) and Pyridine nucleotide-disulphide oxidoreductase (pfam00070). It is also found in NifU nitrogen fixation proteins, in association with NifU-like N terminal domain (pfam01592) and NifU-like domain (pfam01106).
Links
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Statistics
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PSSM-Id: 398152
Aligned: 230 rows
Threshold Bit Score: 30.5743
Threshold Setting Gi: 123633360
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_012997475   403 IICKCNKVSEGDILEAIeRmkkigvkVPSIDSIK--FRTKATTGtCQGgfCRVKIAAILAR 461 Aciduliprofundum boonei
jgi:Ajs_2839   495 PVCACTDHGHQAVREAIrTh-----rLLTVDGVFrfLEWKTPNG-CAT--CRPAVNYYLIS 547 Acidovorax sp. JS42
WP_011800808   491 amCGCTDAGHQAVRDAIrKn-----kLLSITEVYqfLEWRTPNG-CAS--CRPAVNYYVTS 543 Polaromonas naphthalenivorans
WP_014002650   487 aLCACTDYSHQEVRDAIhKq-----rLLSVRETFrsLGWRNPGG-CAT--CRPAVNYYVRT 539 Acidithiobacillus caldus
Q127V2         487 aVCGCTDHSHQEVRDTIkSl-----hLLTIADVYktMEWRTPNG-CAS--CRPAINYYLIS 539 Polaromonas sp. JS666
jgi:Lcho_2678  495 aVCACTDASHQEVRDTIrNe-----kILTIDGVYqrLGWKTPNG-CAS--CRPALNYYLIS 547 Leptothrix cholodnii SP-6
Q1QJ68         487 TVCECTDAGHDEVRRAIlAe-----nLKTMEAVRdrFGWKNPEG-CAK--CRPALNYYLlc 539 Nitrobacter hamburgensis X14
WP_015828604   483 TVCGCTDLGPGDVRRLIvAk-----eLKSIPAIMqeLGWKTSGG-CAK--CRPALNYYLIA 535 Hirschia baltica
zuci:PHZ_c0969 488 PVCGCTGKGHDEVRRRIlAe-----gLKSMPAVMqaLEWTTPDG-CPA--CRPALNYYLlc 540 Phenylobacterium zucineum HLK1
Q9AAI3         490 PICKCSPKTHGDVRRAIvDq-----gLKSMPAVMqaLEWSTPDG-CAS--CRPALNYYLlc 542 Caulobacter vibrioides
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