Conserved Protein Domain Family
Ground-like

?
pfam04155: Ground-like 
Ground-like domain
This family consists of the ground-like domain and is specific to C.elegans. It has been proposed that the ground-like domain containing proteins may bind and modulate the activity of Patched-like membrane molecules, reminiscent of the modulating activities of neuropeptides.
Statistics
?
PSSM-Id: 398020
Aligned: 89 rows
Threshold Bit Score: 55.324
Threshold Setting Gi: 308482602
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_003103504   26 GEKCNDVILYDIIKkvrflfETHsfsisfkasktTVDPTEIRQ---TAMKTMEEVFPLsrSMGCICTDHKFQFpN-FTNH 101  Caenorhabditi...
Q9TYW7         33 QLFCCDSTIKTVVEtg---mQTLdlfg----aggPQTLGPIVQ---ALSTFVQQHFKT--AYEIVMAPKDFVLnThYNGT 100  Caenorhabditi...
O02154         35 DLYCCDSTIKTVIKrg---iRTLsyfg----ddgPQTLGPIVQ---GLSTYVQRHYGV--AYEIVLAPKGFILnSnYNGS 102  Caenorhabditi...
EGT59436      288 GNKCCDGRLASTMRda---mRHMatsp----dfgNGKEGIIAAifqELQQKVQQRFKK--SFEVIVSRSDFVVsTyTAGD 358  Caenorhabditi...
4_pfamImport    1 GNKCCDGRLASTMRda---mRQMatsp----sfgRGKEGIIVS---ELQQKVQERFKK--SYEVIVSQSDFAVsSwASGQ 68  
Q21835        288 GNRCCDGRLASTMRda---mRQMatsp----dfgQGKEGIIAA---ELQQKVQQRFQK--SYEIIVSQSDFVIsTyTAGD 355  Caenorhabditi...
Q9XV14         40 lVECCDKPLKQLIL------DTIhgt-----nfeSLANGDFAK---IVQRRAQMEFHS--SFETIVSKTNFAIsShYHGP 103  Caenorhabditi...
Q21835         56 tVECCDEELSKLIH------KTIldag----nnaKL--GNLAK---FIQRRSQLFYHM--SFETIVSRENFAIsThYHGT 118  Caenorhabditi...
Q9XUV2         50 iVECCDESLKDLLQnfir-------------qgkAGSLGDLAK---VIQRKAQLEFHA--SFEAIICKSNFAIsThYHGS 111  Caenorhabditi...
EGT34445       35 klFCCDSTIKTVVEtg---mKTLdlfg----aggPQTLGPIVQ---ALSSFVQRHFKV--AYEIVMAPKDFVLnTnYNGT 102  Caenorhabditi...
XP_003103504  102 RYCSVKVSTFRCHAI 116  Caenorhabditis remanei
Q9TYW7        101 SLCKFQSNSYTLAIY 115  Caenorhabditis elegans
O02154        103 SVCKFETNSYTMAVY 117  Caenorhabditis elegans
EGT59436      359 TFCKFENRDFYILAY 373  Caenorhabditis brenneri
4_pfamImport   69 SFCKFESKGFYILAY 83  
Q21835        356 NFCKFDNKGFYILAY 370  Caenorhabditis elegans
Q9XV14        104 HTCRVHKKGHYLLVY 118  Caenorhabditis elegans
Q21835        119 HSCRVHDNNLYYLVY 133  Caenorhabditis elegans
Q9XUV2        112 QACKVHVENQYFLIY 126  Caenorhabditis elegans
EGT34445      103 SLCKFQSNAYTLAVY 117  Caenorhabditis brenneri
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap