3DWL


Conserved Protein Domain Family
P21-Arc

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pfam04062: P21-Arc 
ARP2/3 complex ARPC3 (21 kDa) subunit
The seven component ARP2/3 actin-organising complex is involved in actin assembly and function.
Statistics
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PSSM-Id: 397948
Aligned: 89 rows
Threshold Bit Score: 207.738
Threshold Setting Gi: 122021189
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3DWL_E         1 MPAYHSSFLSLt----------dVPTTGNIAMLPLK--TKFR--GPAYPA-------DESQMDIIDECIGLFRANCFFRN 59 
XP_647903      4 sgAYHSELDKDi-----------VQKAGNFPLMQFK--TKVKv-NPKFLL-------KGDDMDIVDEAITYYKANVFYKN 62  Entamoeba histo...
XP_001761158   1 -mVYHSSLKVDd----------eIQQACSCPILPLK--SHIR--GPAPTA-------EAGSMDIIDEAINYFRANVLFRK 58  Physcomitrella ...
XP_002975315   1 -mVYHSSFKDEs----------gAGQACGCPLLPLR--TPIK--GPAPLA-------DPGQFDIIDEAINFFRANVLFRK 58  Selaginella moe...
XP_009395285   1 -mVYHSSFVDEe----------gITKACGCPLLPLK--THIK--GPAPVS-------DQDKIDIVDEAITFFRANVFFKN 58  wild Malaysian ...
XP_002955200   1 -mAYHSLFNDSgd---------rYRLCCGCPLIPLN--VSSA--APSDa--------DGTTLDPIDEAIELFRPNSLFKS 58  Volvox carteri ...
Q4DBS1         1 ---mHSRWNGYe-----------ESSLLGCGVYPLRrtSRLTppGPAPRMdemieegEEEPQDIVDEAFYFFKPHMFFRN 66  Trypanosoma cruzi
EFC48429       1 MPAYHSSFKDAk-----------cEVYCGTAILPLK--TKVK--GPAPKEl------DENKEDIIDEVLKFFKSNMLFRS 59  Naegleria gruberi
EGD82319       1 MPAYKSAYTKRftqaakqgeqlgFETIGGIPLLPIHa-RNSK--GPAPRPs------PDETTDIIDETIRFFRANVFFAS 71  Salpingoeca ros...
XP_001746449   1 MPAYHSSHNQRq----------gVKLVGGVALLPFHa-HHTR--GPAPRPg------PEDEVDIIDETLKFFKANVFFQS 61  Monosiga brevic...
3DWL_E        60 F--EIKGPADRTLIYGTLFISECLGRVN---GLNYRDAERQLNSLALENFSIPGSAGFPLNALYAPP-LSPQDAEIMRTY 133
XP_647903     63 FdmSI-CEADKLLVYLIFYIQSLLLKFN---GHTKVECDKMAYSLAIENFALPGDGKFCLGGIVEPL-KASEK-EVVRQY 136 Entamoeba histo...
XP_001761158  59 F--EIKGPADKLLVYLTLYINMALKRIEa--CKTEADGVKAIINLGLEKFPIPGEPGFPLGGLFTAP-QTREEGDLLRNY 133 Physcomitrella ...
XP_002975315  59 F--EVKSSADKLLIYLTMYINMALKRIEt--CKSEAEGIKVIINLGLEKFPIPGEPDFPLGGLFTTP-GSPQEADLFRNY 133 Selaginella moe...
XP_009395285  59 F--DIKSPADKLLIYLTFYINVALKRLEg--CRTLAVGTKAIINLGLEKVPVPGEPGFPFPGLFSVP-QSQDEAELFRNY 133 wild Malaysian ...
XP_002955200  59 F--DIRGPGDKLLVYLILFINSCLRQRKp--PPSREEARALLFATAHDRFPLPGQAGFPLGALMLAP-ASREEEETIRSY 133 Volvox carteri ...
Q4DBS1        67 F--PIKGAGDRVILYLTMYLHECLKKIV---QLKREEAHSVLLNYATMPFASPGEKDFPFNAFF--PaGNEEEQEKWREY 139 Trypanosoma cruzi
EFC48429      60 Y--QVESPADRTLIYLTMYTHFLLKHTEnkkTTKKADADKLYFQLSEEALPGPGDSSFALIAFYDKP-RDTNEKKQWDSY 136 Naegleria gruberi
EGD82319      72 Y--KIDAAPDRLMVYLTLFCHQCVMRLAk--AKTKDDAAREMYQLGIENFTLPTDAGFQLKGFFEKL-DQKSSQDKLRAY 146 Salpingoeca ros...
XP_001746449  62 Y--EVRGPADLLLIYLTLYTHQCIMRVAk--TTSKDGAQRALFQLAQENFSLPCDSGFQLSSYYQPL-SSKSDGDELRAY 136 Monosiga brevic...
3DWL_E       134 LTQFRQELAYRLLSHVYa------tEKD-----HPSKWWTCFSKRRFMNKAL 174
XP_647903    137 MTAIRNETGLRLTQAVF--------KNDp---tKCDKWWMCFNKRKFLNKTi 177 Entamoeba histolytica HM-1:IMSS
XP_001761158 134 FKQVREETSGRLMEKVYr-------QNG-----TPNKWWLAFAKRKFMNimm 173 Physcomitrella patens
XP_002975315 134 LKQLREETSGRLMGRVYr-------PNG-----SPNKWWLAFAKRRFMNill 173 Selaginella moellendorffii
XP_009395285 134 LKQIREETSGRLLNCAYr-------PNG-----TPNKWWLAFAKRKFMNivv 173 wild Malaysian banana
XP_002955200 134 LRQCREEAGRRLLERLYaapgaaggEGGtavaaAPNRHWLAFANRRFLDRTi 185 Volvox carteri f. nagariensis
Q4DBS1       140 AKQLRLEANARLIEKVFlf----peKDG-----TGNKFWMAFAKRPFLASs- 181 Trypanosoma cruzi
EFC48429     137 MRQAKEELGLRLAKLIFk-------EDG-----VADKYWMQFSKRKFLGKAf 176 Naegleria gruberi
EGD82319     147 LQQCRQELSARMAEVVLd-------ASG-----KPSKWWTCFAKRKFLGKAL 186 Salpingoeca rosetta
XP_001746449 137 LKQCREELGNRLAERCCd-------ASD-----KPSKWWVCFAKRKFLGKSL 176 Monosiga brevicollis MX1
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