1VKD


Conserved Protein Domain Family
Glyco_hydro_130

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pfam04041: Glyco_hydro_130 
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beta-1,4-mannooligosaccharide phosphorylase
This is a family of glycosyl-hydrolases of the CAZy GH130 family. Several have been characterized as mannosylglucose phosphorylase. This enzyme is part of the mannan catalytic pathway and feeds into the glycolysis cycle. Specifically it catalyzes the reversible phosphorolysis of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine. This family was noted to belong to the Beta fructosidase superfamily in.
Statistics
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PSSM-Id: 397932
Aligned: 6 rows
Threshold Bit Score: 331.758
Threshold Setting Gi: 74543073
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VKD_F  16 FTEKIPNIPWEERPEGYTGPVWRYsknpiigrnPVPKGARVFNSAVVPYNGE------FVGVFRIDH-KNTRP-FLHFGR 87  Thermotoga maritima MSB8
Q9YFA2  23 RYRRRHTVDIARRIGYIRPENVELer------gSTRRVVSFFNSTLRLAREGlevygrVVVGYYKYV-SLVASlRIGLED 95  Aeropyrum pernix
Q9WZN9  15 SLRKDETIDVFNRVTYFFPKDFVIt-------nYPRNPVAVFNPGAVLVGKAlhvfprLIFDYYKYV-SSIGHfIVNIDD 86  Thermotoga maritima
O67215  17 EKRRFETKDLVKRLKVITGHDIHIqn------yPVETPRVAFNPSIHVFENRlriyarVVMGYYTYT-SAIAEfDIDLEE 89  Aquifex aeolicus
Q9X2G7   4 KLERHPANPILE-PSPYFLWESRF----------------VFNPAVV-YDGEl-----FHLLYRAQG-EDMVS-RIGYAV 58  Thermotoga maritima
Q9HH03  31 PPKKIPQ-PILS-PS-REGFDSRN----------------TYNPAVI-KEKDr-----IVMLYRAESkEDKLTgRIGLAI 85  Pyrococcus furiosus
1VKD_F  88 SKDG------INWEIEPEeiQWVDVNGEPFQpsyAYDPRVVKIEDTYYITFC-TDDHGPTIGVGXTKDFKTFVRLP---- 156 Thermotoga maritima MSB8
Q9YFA2  96 ISSGrcsrceEKHTARPE--VLPGDWIDFWG---AEDPRYTSVNSHDVLTYTgRTLAYYSSSVGQTFPVVAVRRAPngew 170 Aeropyrum pernix
Q9WZN9  87 LLNGe-----VKKPLEMEvvFWPRDIQEFLG---CEDPRVFFRNSRFELLYTaKGYKDWSQEGKPHTDFLAYAVLD---- 154 Thermotoga maritima
O67215  90 LYNP------ERKTYEANltVLPNIKYDLWG---VEDPRVYEIDGKLFMTYTgRTVNYFRTDIRTERTLPVTARYEngqw 160 Aquifex aeolicus
Q9X2G7  59 STDG------IHFNKFEKpvFAPKSDDELYG---VEDPRITKIGDEYYMVYTaYSPRGVRIAMASTKNFITWKRYG---- 125 Thermotoga maritima
Q9HH03  86 SYDG------INFFRHPEpiIEPEYKWESVG---VEDPRIVKVGKTYYMTYTgYDGKTARLCLATSKNMLTWKKHG---- 152 Pyrococcus furiosus
1VKD_F 157 NAYVPFN----------RNGVLFPRKI-----NgKYVXLNRpsdnghtpFGDIFLSES--PDXIHwGNHRFV----LG-- 213 Thermotoga maritima MSB8
Q9YFA2 171 VKEAYITlepdeaplatSIKNAFILSH-----RgILLAFYRvh----dvSGRFHLLAGi-SDGLP-EGPISP----LApk 235 Aeropyrum pernix
Q9WZN9 155 EDLNLIEkryi--siksTLGEYVPVSM-----KdSSFVESK--------VILTRLTVG--DAKVCwRGRLEGsyidLY-- 215 Thermotoga maritima
O67215 161 KKIAVFRmpedirsfvvSDKNAFLVKT-----D-KLMLYHRlh----mlNEKFYLAVCnvPEEVLyTNEFKEi--eIG-- 226 Aquifex aeolicus
Q9X2G7 126 VVIPEVDn---------KDAALFPEKI-----NgKYVMFHRi-------PPDMWLAFS--DDLVHwDNFVK-----IA-- 175 Thermotoga maritima
Q9HH03 153 PIFEGFEykknnikgwtKSGAILPKKLekgnfKgNYLMYFG--------DSNIWMAVS--KDLVNwEYMKEP----VL-- 216 Pyrococcus furiosus
1VKD_F 214 RSSYNWWEN---LKIGAGPYPIETSEG-WLLIYHGv-tLT---CNGYVYSFGAALLDLDDpsK---VLYRSRYYLLTPEE 282 Thermotoga maritima MSB8
Q9YFA2 236 SVWRIMDPApfeEKIGWATPVNGYKGGsLLVLLHG---VD---TEQQVYRVLAAELDLEG--RelvLKAVTPEYIMEPST 307 Aeropyrum pernix
Q9WZN9 216 SLDPVFFPEeweTKVGWSTNTVEVKEG-YLVGWH----AV---LKDLTYKNGLALVDGRG------RLLGTTNYVLSPKG 281 Thermotoga maritima
O67215 227 ENITIMEEApfeTKIGWATPPVKVGEE-NLVLIHG---VD---KELTAYRVFAVLMNKEG--Y---FTAVTPFYILEPKK 294 Aquifex aeolicus
Q9X2G7 176 SPRPGMWDD---LKIGVGAPPIKTEYG-WLVLYHGvqnTG---TSRPIYRLGFMLLDLEDptK---VIKRSKEPILEPEE 245 Thermotoga maritima
Q9HH03 217 SPREGYFDN---VLVEPGPPLFETSYG--IALIYn---SAgryGDKLKYKVGVVIFDKEYpdK---VVARTETPLMVPEY 285 Pyrococcus furiosus
1VKD_F 283 EYETVGFVPNVVFPCAA-LCDADtgrVAIYYGAADTHVALAFGYideiVDFVKR 335 Thermotoga maritima MSB8
Q9YFA2 308 LEERFGDRPYTIFPCGAwLVDGE---IIVSYGAADTATGLASIP----LDVLEE 354 Aeropyrum pernix
Q9WZN9 282 VIEEYGDRIRVIFGCGL-VVYGGr--VIWIGGVSDWAIGVFETSereiMNLMKE 332 Thermotoga maritima
O67215 295 IYEVYGDRPFVVFPCGI-QRLENk--LLISYGGADTVVVIGEIDleelMNILYE 345 Aquifex aeolicus
Q9X2G7 246 DWEKFGGVPNVVF-SDA-MIEYNg-yYYVYYGAADNCIALATIPvekvMKWCRE 296 Thermotoga maritima
Q9HH03 286 EWELYGHVNNVVF-VEG-MVEHEn-kILLYYGGADRHIGLAYWT-------TDL 329 Pyrococcus furiosus
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