Conserved Protein Domain Family
DUF368

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pfam04018: DUF368 
Domain of unknown function (DUF368)
Predicted transmembrane domain of unknown function. Family members have between 6 and 9 predicted transmembrane segments.
Statistics
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Structure
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pfam04018 is a member of the superfamily cl00893.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Hmuk_0288                   32 MGSADATPGISGGTVALIMGIYERLIAAITAITPERARRFLRAltpvdggvslrRAVAVLE----EVDVWFLLALVGGVG 107
WP_006183249                    25 MGTADALPGVSGGTVALLLGFYGRLIAAVTAFTPGRALAVLRGyhpd----rraRAREALL----ELDLDFLLPLGVGMV 96  Natrinema pellirubrum...
KoreaUniversity:VAB18032_05145  16 IGVAEAVPGISGGTIALVTGVYERVIASAGHV-VSAIRYAASDlprg---rggiRARQQLR----QVHWEVVVPLLIGML 87 
CBBU:CRES_0915                  16 VGMAELVPGVSGGTIALVTGIYERVLFNANRF-LDAAKTLPSDr---------pEALHRFR----RLDWALLIPMVFGMG 81 
CeBiTec:A605_06705              31 IGMAELVPGISGGTVALVVGIYERALNAGNQL-----------------------IKRQFA----KVDWWFLVAVGLGMV 83 
Q8XKL6                          12 MALADSVPGVSGGTIAFIMGFYNKFISSLNAL-----------------------TSTKKTdvskKDAIIFLLKLGIGWI 68  Clostridium perfringens...
AGN25702                        11 MAIADSVPGVSGGTIAFLLGFYDKFIGAFNNI-----------------------LSGNKEq--rINAAKFLLKLGAGWI 65 
O83334                          14 IGAANVVPGLSGGTVALLCGTWELLIAAIALD---------RA-----------HLCRQWR---------RLLALAGGIV 64  Treponema pallidum...
CCY67926                        32 IGLGAVLPGISGGVLCVVFGVYKPIMELLSHPfk-----------------------------aiKKYAKLLIPIVIGIG 82 
CCX38445                        21 VGVGAVLPGISGGVLCVVFGIYKPVMELLSNPvk-----------------------------kfKTHVPRLFPVILGAA 71 
jgi:Hmuk_0288                  108 TAVVIVARIVHVASEETPVLLYGALFGLIGASAVILLRALSI--------------------------E-TATHAVAAAS 160
WP_006183249                    97 TAVVLIADLVSSLAESHPVAIFGFFTGLIAASAITLGRSLEF--------------------------A-SPAHVAAALA 149 Natrinema pellirubrum...
KoreaUniversity:VAB18032_05145  88 PGLLIAAKTLEPLLTDYPEQTRGLFLGLVLASVLVPVSMVGAp-------------------------W-RRKEIAALVL 141
CBBU:CRES_0915                  82 AVVVTMSGVMESFVTDHPSISRALFFGMVLVSISVPLTMIAPlraila---------------nflkpK-FLPVTLAALV 145
CeBiTec:A605_06705              84 AAVFTMSTVLVNFVEGYPELSRGLFLGMVAVSILVPVGMMDPedl---------------------rrK-LPVALPVFLL 141
Q8XKL6                          69 TGMVLSILFIASIFDKEIYKISSLFTGFIIFSIPIIISEDKEsl------------------------kkNYGYIIYAIL 124 Clostridium perfringens...
AGN25702                        66 IGFIVCVLILSSIFQSNIYQISSLFLGLIIFAIPVIIMAEKEcl------------------------kgKYANLIFTII 121
O83334                          65 VGIGVCARFMRALYEAFPHLTNAFLAGVLLASVPSLRNRVRAasvaaehsvqaegtarghvgdaarrvWcAVRIIFFVLL 144 Treponema pallidum...
CCY67926                        83 IGFLAISKLLGFLLNKYPDPSVCLFVGLIAGMLPSLFREAGEkgrs---------------------kgsFISLGICFVV 141
CCX38445                        72 LGFLGVAKILAFFLEKYPDQSVCLFVGLIGGMLPSLFREAGEqgrt---------------------kgsWISLVAAFVI 130
jgi:Hmuk_0288                  161 GFVLAFVLSGPA--------------------SPLGteGLLV----------VFLGGAVSVSAMILPGISGSLLLVVLGQ 210
WP_006183249                   150 GTTLALLVAADV--------------------VQLPgsGPAV----------ILVAGAVAISAMILPGVSGSLILILLGQ 199 Natrinema pellirubrum...
KoreaUniversity:VAB18032_05145 142 AAVGAFALTGLPq------------------aTLDP--HPLI----------VLMAAAIAVCALVMPGVSGSFLLLTVGL 191
CBBU:CRES_0915                 146 AAAATFFLTGITsa-----------------pQSDP--NLLI----------VFCAAAVAICALVLPGVSGSFFLLAVGL 196
CeBiTec:A605_06705             142 SAVVAFFATGFTsa-----------------pQENP--SLVI----------IFFAAAVAVCALVMPGISGSFLLLALGL 192
Q8XKL6                         125 GIAIVAAITYFNpa-----------------tGSAKgtSLVLnefslplalyVFFAGMIAISAMVLPGISGSTLLLIFGL 187 Clostridium perfringens...
AGN25702                       122 GIVIVCLITYYNp-------------------vSGEgsSINLtqpsielalyVFVAAIITISAMVLPGISGSTLLLAMGL 182
O83334                         145 GFVAVCAFSRMQhardassatapasvqttavlTTAHtrGFVA----------TVCAGALAAAAMLTPGFSGSLVLLLAGV 214 Treponema pallidum...
CCY67926                       142 VLALLLGLNAIH---------------------VTIvpNFGW----------YLFCGFCIALSVIAPGMSFSTLLMPLGL 190
CCX38445                       131 IMALLLSLNLLS---------------------VTIvpSFGW----------YLFCGFCAALSIIAPGMSFSTLLMPLGL 179
jgi:Hmuk_0288                  211 YERLSGALTTFVdgllavltgrpaagLvdagTV-----------------VVTFILGGLVGLFTISRLIRRALDRNRGAT 273
WP_006183249                   200 YVYLSSELSAFVraaldllgggslsaVvdpgTT-----------------VALFVTGGVVGLVTIARIVRAALTRNRGVT 262 Natrinema pellirubrum...
KoreaUniversity:VAB18032_05145 192 YEPTITALNDRD--------------F----GY-----------------LAIFATGMVIGLSLFVKLLQWLLEEHRRMT 236
CBBU:CRES_0915                 197 YSATLAAVSDRN--------------L----AY-----------------IAVFAAGALTGIVLFVRTLEKLLTRHRTMT 241
CeBiTec:A605_06705             193 YSPVMASLSNRE--------------W----DV-----------------IIVFMLGALLGIILFVRGLTWILENHRTLT 237
Q8XKL6                         188 YAPVVNGVKEVLtfn--------fsyL----PM-----------------LMVFGLGVVVGIITTIRLIKFLLSNYRSQM 238 Clostridium perfringens...
AGN25702                       183 YLPLLNAVKEVIhld--------ssyL----LM-----------------LCIFALGLIVGIFSVIKIVKHCLDAYRSQT 233
O83334                         215 YQPLLSVLSLRA--------------VeqggGVtgasvisrlcsahvwglLFPLCVGMGIGLLGAARVLRAWFRLYPVSA 280 Treponema pallidum...
CCY67926                       191 YTPLVEGIGNLD--------------F----SV-----------------LIPAGIGALITVILLAKAIDTLMNRHYSIV 235
CCX38445                       180 YTPFVDGIGNLD--------------L----GV-----------------LAPAGIGAVVTILCLAKAVDALFNHFYSFA 224
jgi:Hmuk_0288                  274 LAFLVALVVGALRAPITeLSTREAVTWT 301
WP_006183249                   263 LLFLIGLIAGSVPAPLHnIGETTAWTTe 290 Natrinema pellirubrum
KoreaUniversity:VAB18032_05145 237 LAVMSGALLGSLRALWP-WQSDERTLHA 263
CBBU:CRES_0915                 242 LSVMAGLMLGSLRALWP-WQDTDATLQS 268
CeBiTec:A605_06705             238 LTVMSGLMLGSLRALWP-WQTGDADLLA 264
Q8XKL6                         239 IYFIIGLMIGSIYAVFM-GPTTLEIPKA 265 Clostridium perfringens
AGN25702                       234 IYLILGLMIGSIYSIIM-GATTLEVPQP 260
O83334                         281 HACVCGLVLGSSVTLFP--RGTAAGMQD 306 Treponema pallidum
CCY67926                       236 FHGIIGIVIAATIVIIP-FKSFTVGIKE 262
CCX38445                       225 FHAIVGIVIAATLVIIP-FGSFTASVGS 251
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