Conserved Protein Domain Family
DUF368

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pfam04018: DUF368 
Domain of unknown function (DUF368)
Predicted transmembrane domain of unknown function. Family members have between 6 and 9 predicted transmembrane segments.
Statistics
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PSSM-Id: 397913
Aligned: 61 rows
Threshold Bit Score: 148.472
Threshold Setting Gi: 81344757
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Hmuk_0288                   32 MGSADATPGISGGTVALIMGIYERLIAAITAItPERARRFLRAltpvdggvslrRAVAVLE----EVDVWFLLALVGGVG 107 Halomicrobium mukohataei DSM 12286...
KoreaUniversity:VAB18032_05145  16 IGVAEAVPGISGGTIALVTGVYERVIASAGHV-VSAIRYAASDlprg---rggiRARQQLR----QVHWEVVVPLLIGML 87  Verrucosispora maris AB-18-032...
Q47MN8                          18 IGTAETVPGISGGTVALITGVYESLINSAGHV-VTAVRLLVTDllrg---kglaRARAELT----RADWGTVLAVLVGMV 89  Thermobifida fusca YX...
CBBU:CRES_0915                  16 VGMAELVPGVSGGTIALVTGIYERVLFNANRF-LDAAKTLPSDr---------pEALHRFR----RLDWALLIPMVFGMG 81  Corynebacterium resistens DSM 45100...
CeBiTec:A605_06705              31 IGMAELVPGISGGTVALVVGIYERALNAGNQL-----------------------IKRQFA----KVDWWFLVAVGLGMV 83  Corynebacterium halotolerans YIM 70093 = DSM 44683...
Q8XKL6                          12 MALADSVPGVSGGTIAFIMGFYNKFISSLNAL-----------------------TSTKKTdvskKDAIIFLLKLGIGWI 68  Clostridium perfringens...
AGN25702                        11 MAIADSVPGVSGGTIAFLLGFYDKFIGAFNNI-----------------------LSGNKEq--rINAAKFLLKLGAGWI 65  Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1...
O83334                          14 IGAANVVPGLSGGTVALLCGTWELLIAAIALD---------RA-----------HLCRQWR---------RLLALAGGIV 64  Treponema pallidum...
CDA98156                        15 IGLGAVLPGISGGVLSVVFGVYRPIMELLSDPvh-----------------------------kwRTHLPELFPYMIGSA 65  Firmicutes bacterium CAG:65...
CCX38445                        21 VGVGAVLPGISGGVLCVVFGIYKPVMELLSNPvk-----------------------------kfKTHVPRLFPVILGAA 71  Clostridium sp. CAG:1013...
jgi:Hmuk_0288                  108 TAVVIVARIVHVASEETPVLLYGALFGLIGASAVILLRALSI--------------------------E-TATHAVAAAS 160 Halomicrobium mukohataei DSM 12286...
KoreaUniversity:VAB18032_05145  88 PGLLIAAKTLEPLLTDYPEQTRGLFLGLVLASVLVPVSMVGAp-------------------------W-RRKEIAALVL 141 Verrucosispora maris AB-18-032...
Q47MN8                          90 PAVLVAARVIAPLVEHNPAESHALFFGLVLASLWVPYSSSGRr-------------------------W-RIGDYLLALL 143 Thermobifida fusca YX...
CBBU:CRES_0915                  82 AVVVTMSGVMESFVTDHPSISRALFFGMVLVSISVPLTMIAPlraila---------------nflkpK-FLPVTLAALV 145 Corynebacterium resistens DSM 45100...
CeBiTec:A605_06705              84 AAVFTMSTVLVNFVEGYPELSRGLFLGMVAVSILVPVGMMDPedl---------------------rrK-LPVALPVFLL 141 Corynebacterium halotolerans YIM 70093 = DSM 44683...
Q8XKL6                          69 TGMVLSILFIASIFDKEIYKISSLFTGFIIFSIPIIISEDKEsl------------------------kkNYGYIIYAIL 124 Clostridium perfringens...
AGN25702                        66 IGFIVCVLILSSIFQSNIYQISSLFLGLIIFAIPVIIMAEKEcl------------------------kgKYANLIFTII 121 Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1...
O83334                          65 VGIGVCARFMRALYEAFPHLTNAFLAGVLLASVPSLRNRVRAasvaaehsvqaegtarghvgdaarrvWcAVRIIFFVLL 144 Treponema pallidum...
CDA98156                        66 AGFLGVANLLSYVLETYPEPSVCVFVGLIVGMLPSLWREAGEqgrn---------------------vgnVILSCVTLVA 124 Firmicutes bacterium CAG:65...
CCX38445                        72 LGFLGVAKILAFFLEKYPDQSVCLFVGLIGGMLPSLFREAGEqgrt---------------------kgsWISLVAAFVI 130 Clostridium sp. CAG:1013...
jgi:Hmuk_0288                  161 GFVLAFVLSGPA--------------------SPLGteGLLV----------VFLGGAVSVSAMILPGISGSLLLVVLGQ 210 Halomicrobium mukohataei DSM 12286...
KoreaUniversity:VAB18032_05145 142 AAVGAFALTGLPq------------------aTLDP--HPLI----------VLMAAAIAVCALVMPGVSGSFLLLTVGL 191 Verrucosispora maris AB-18-032...
Q47MN8                         144 MAAAAFLFTGVPs------------------tTVDP--HPLI----------VMAAAAVAICALVLPGISGSFILLTVGL 193 Thermobifida fusca YX...
CBBU:CRES_0915                 146 AAAATFFLTGITsa-----------------pQSDP--NLLI----------VFCAAAVAICALVLPGVSGSFFLLAVGL 196 Corynebacterium resistens DSM 45100...
CeBiTec:A605_06705             142 SAVVAFFATGFTsa-----------------pQENP--SLVI----------IFFAAAVAVCALVMPGISGSFLLLALGL 192 Corynebacterium halotolerans YIM 70093 = DSM 44683...
Q8XKL6                         125 GIAIVAAITYFNpa-----------------tGSAKgtSLVLnefslplalyVFFAGMIAISAMVLPGISGSTLLLIFGL 187 Clostridium perfringens...
AGN25702                       122 GIVIVCLITYYNp-------------------vSGEgsSINLtqpsielalyVFVAAIITISAMVLPGISGSTLLLAMGL 182 Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1...
O83334                         145 GFVAVCAFSRMQhardassatapasvqttavlTTAHtrGFVA----------TVCAGALAAAAMLTPGFSGSLVLLLAGV 214 Treponema pallidum...
CDA98156                       125 MLSLLFWLQNSQ---------------------NTVepGFFS----------FLFCGFAFALSVIAPGMSFSTILMPLGL 173 Firmicutes bacterium CAG:65...
CCX38445                       131 IMALLLSLNLLS---------------------VTIvpSFGW----------YLFCGFCAALSIIAPGMSFSTLLMPLGL 179 Clostridium sp. CAG:1013...
jgi:Hmuk_0288                  211 YERLSGALTTFVdgllavltgrpaagLvdagTV-----------------VVTFILGGLVGLFTISRLIRRALDRNRGAT 273 Halomicrobium mukohataei DSM 12286...
KoreaUniversity:VAB18032_05145 192 YEPTITALNDRD--------------F----GY-----------------LAIFATGMVIGLSLFVKLLQWLLEEHRRMT 236 Verrucosispora maris AB-18-032...
Q47MN8                         194 YLPTMEALNNRD--------------L----GY-----------------IATFVLGATIGLSLFVKLLQFLLDRFHHLT 238 Thermobifida fusca YX...
CBBU:CRES_0915                 197 YSATLAAVSDRN--------------L----AY-----------------IAVFAAGALTGIVLFVRTLEKLLTRHRTMT 241 Corynebacterium resistens DSM 45100...
CeBiTec:A605_06705             193 YSPVMASLSNRE--------------W----DV-----------------IIVFMLGALLGIILFVRGLTWILENHRTLT 237 Corynebacterium halotolerans YIM 70093 = DSM 44683...
Q8XKL6                         188 YAPVVNGVKEVLtfn--------fsyL----PM-----------------LMVFGLGVVVGIITTIRLIKFLLSNYRSQM 238 Clostridium perfringens...
AGN25702                       183 YLPLLNAVKEVIhld--------ssyL----LM-----------------LCIFALGLIVGIFSVIKIVKHCLDAYRSQT 233 Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1...
O83334                         215 YQPLLSVLSLRA--------------VeqggGVtgasvisrlcsahvwglLFPLCVGMGIGLLGAARVLRAWFRLYPVSA 280 Treponema pallidum...
CDA98156                       174 YTPFVEGIGHVR--------------L----EV-----------------LLPGVAGCVVTFLCLAKLVNRLFERHYALM 218 Firmicutes bacterium CAG:65...
CCX38445                       180 YTPFVDGIGNLD--------------L----GV-----------------LAPAGIGAVVTILCLAKAVDALFNHFYSFA 224 Clostridium sp. CAG:1013...
jgi:Hmuk_0288                  274 LAFLVALVVGALRAPITeLSTREAVTWT 301 Halomicrobium mukohataei DSM 12286
KoreaUniversity:VAB18032_05145 237 LAVMSGALLGSLRALWP-WQSDERTLHA 263 Verrucosispora maris AB-18-032
Q47MN8                         239 LVVMTGLMAGSLRALWP-WQDDDRTLLA 265 Thermobifida fusca YX
CBBU:CRES_0915                 242 LSVMAGLMLGSLRALWP-WQDTDATLQS 268 Corynebacterium resistens DSM 45100
CeBiTec:A605_06705             238 LTVMSGLMLGSLRALWP-WQTGDADLLA 264 Corynebacterium halotolerans YIM 70093 = DSM 44683
Q8XKL6                         239 IYFIIGLMIGSIYAVFM-GPTTLEIPKA 265 Clostridium perfringens
AGN25702                       234 IYLILGLMIGSIYSIIM-GATTLEVPQP 260 Candidatus Methanomassiliicoccus intestinalis Iss...
O83334                         281 HACVCGLVLGSSVTLFP--RGTAAGMQD 306 Treponema pallidum
CDA98156                       219 FHGILGIVGAATVMTVP-WGSFTISADA 245 Firmicutes bacterium CAG:65
CCX38445                       225 FHAIVGIVIAATLVIIP-FGSFTASVGS 251 Clostridium sp. CAG:1013
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