4WFD


Conserved Protein Domain Family
Sas10_Utp3

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pfam04000: Sas10_Utp3 
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Sas10/Utp3/C1D family
This family contains Utp3 and LCP5 which are components of the U3 ribonucleoprotein complex. It also includes the human C1D protein and Saccharomyces cerevisiae YHR081W (rrp47), an exosome-associated protein required for the 3' processing of stable RNAs, and Sas10 which has been identified as a regulator of chromatin silencing. This family also includes the human protein Neuroguidin an initiation factor 4E (eIF4E) binding protein.
Statistics
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PSSM-Id: 397897
Aligned: 321 rows
Threshold Bit Score: 31.0904
Threshold Setting Gi: 451848385
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4WFD_H               11 VRSFSKALDELKPEIEklt----------skSLDEq---lLLLS---DERAKLELInrYAYVLSSLMFaNMK-VLGvkd- 72  Saccharo...
EEP81052            233 FEPLSAEFVVLQQVHQelseavaqiipgvgnS-----------Is--VPLIKWRAL--SAYLGAICMY--LVlLASparg 295 Uncinoca...
EFW16552            233 FEPLSKEFLVLQQLHQelsealkqraastdnD-----------Is--ALLIKWRVL--SAYLGAISMY--FVlLVSpard 295 Coccidio...
EEQ85164            234 FEPLSKDFLSLQCVHEelaaam---qnadnlANGAgyssgTDNDyvpLPVVKFRAL--SAYLGAISMY-FFL-LTSpsrn 306 Blastomy...
EDN03923            293 FEPLSKDFLSLQHLHEefavaaqnaensvngRGLShq-agGDHVp--LPVIKFRTL--SAYLGAISMY--FFlLTSpsrd 365 Histopla...
EFR01529            241 FVPLSKDYTDLQPRYQelsaavdgarksrkeTSS-------DKTp--LSVLQFRAL--AAYLGVISMY--FVlLTSparn 307 Nannizzi...
WGS:ACPH:TERG_07947 242 FLPLSRDYAELQPRYRelsvavdgprktckeTLG-------EKTp--LSVLQFRAL--AAYLGVISMY--FVlLTSparn 308 Trichoph...
EGE03202            242 FTPLSRDYTDLQPRYQelsvavdrsrnsrkeTP--------DEKt--LSVLQFRAL--AAYLGVISMY--FVlLTSparn 307 Trichoph...
CCX13694            210 FQLLSEEFLELQKLFPalemgaka------------aeavgnkEs--VAIKKWKVS--SAYLGVLSMY--FAiLTDagsd 271 Pyronema...
EHY54224            222 FEPLSKDFLRLQDTYQtlkkeaaq----------------seadrqsVSWTKFRAL--SAYLGAVAMY--LAlLTStksg 281 Exophial...
4WFD_H               73 --------------mspILGELKRVKSYMDK 89  Saccharomyces cerevisiae S288C
EEP81052            296 ckerclaiapaklrehqIMETLVSCRTQWEd 326 Uncinocarpus reesii 1704
EFW16552            296 veqrclamapaqlrehpIMETLLKCRREWEe 326 Coccidioides posadasii str. Silveira
EEQ85164            307 gearla-mspvelrehpIMETLINCKKQWEE 336 Blastomyces dermatitidis ER-3
EDN03923            366 getrla-mspaelrehpIMETLINCKKQWEE 395 Histoplasma capsulatum NAm1
EFR01529            308 stgsclalppaelrehpIMGALVVCRKTWEQ 338 Nannizzia gypsea CBS 118893
WGS:ACPH:TERG_07947 309 gtesclalppaelrehpVMDALVACRKTWEQ 339 Trichophyton rubrum CBS 118892
EGE03202            308 gtegclalppaelrehpVMEALVACRKTWEQ 338 Trichophyton equinum CBS 127.97
CCX13694            272 edgg-----idrvrdhpIMNAILGVRSAWEt 297 Pyronema omphalodes CBS 100304
EHY54224            282 malp-----paelrehpIMNNLVRCRDLWLK 307 Exophiala dermatitidis NIH/UT8656
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