Conserved Protein Domain Family
Utp11

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pfam03998: Utp11 
Utp11 protein
This protein is found to be part of a large ribonucleoprotein complex containing the U3 snoRNA. Depletion of the Utp proteins impedes production of the 18S rRNA, indicating that they are part of the active pre-rRNA processing complex. This large RNP complex has been termed the small subunit (SSU) processome.
Statistics
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PSSM-Id: 397895
Aligned: 165 rows
Threshold Bit Score: 121.213
Threshold Setting Gi: 156083214
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGF97666      11 RQHRERAQPLQRERl--GLLEKHKDYVKRARDYHSKQDRIKKLREKAALKNPDEFYFEMI-KSST-EKGVHv-------- 78  Melampsora lari...
EFA76319      13 REKRERPQPRSVTN---GFLERKKDYKLRADDFNKKRDQLKKLKLKAALKNPEEFRFNMI-NSKV-IKGVH--------- 78  Heterostelium a...
Q55C50        13 RAKQERPQPESSKKk--GFLERKKDYVERAKDYNNKRDTLKKLKLQAAFKNPDEFNYKMI-SSKL-VDGVH--------- 79  Dictyostelium d...
EGC38956      13 KAKSERPQPENTLKk--GFLERKKDYIERARDYSKKKETIKKLKLQAAFKNPEEFSYKMI-SSKL-VDGVH--------- 79  Dictyostelium p...
XP_003386213  13 KRYRERGQPSERKHl--GLLEKHKDYVERAASFKKKAAELKRLHEKARNRNKDEFYYKMI-KTKL-QDGRHviq------ 82  Amphimedon quee...
CDS43510      15 RLHKERSQPAARAKf--GPLPKKKDFILRSRDEEAKRNRIRELKRKALTKNEDEFYFSMH-NTAHsEEKGHipl------ 85  Echinococcus mu...
XP_004035419  13 RKHRERGQLKEREHl--GLLEKKQDYKKRAKHYHKINDILNNLKQKARLKNDDEFYFKMQ-RAKI-IDGKHveqnqeden 88  Ichthyophthiriu...
XP_001021316  13 RKHRERGQLKNREHl--GILEKKKDYIQRAKHYHKINDQLNNLKLKARLKNENEFYHKMT-KAKI-VDGKHvefeeeedd 88  Tetrahymena the...
EFC45750      14 KTKKERSQPKWRRDlgyGTLEKHKDYKVRSRKAHQIEEQKKLLHEQIKNKNEDEYFIDMAhATKT-DTGTTviekiptmk 92  Naegleria gruberi
Q5CT03        11 RVHLERATPVNRLRf--GILERKKDYKIRAKRYHEKENLLKSLSEKARTRNPDEFDFGMV-NSRL-ENGRYkkigsdlqn 86  Cryptosporidium...
EGF97666      79 RSRGN------KALDNDLVVLLKTQ-DFNYVKTCRAIEEKKVNKIREQLGSMVNAISpddsehdeirneilkfiqqdtta 151 Melampsora lari...
EFA76319      79 HTISK------SELDQSDLADIKQQ-DQLYLQSKRISEEKKIARLQSTLQYIDAGVAps--------------------- 130 Heterostelium a...
Q55C50        80 SEISK------TSLKKEQIIDIKTQ-DILYLQSKRRADDKKIERLQATLQYMDSGLEpt--------------------- 131 Dictyostelium d...
EGC38956      80 SEISK------TSLKKEQIIDIKTQ-DILYLQSKRKSEDNKIERLQANLQYLDSIEPn---------------------- 130 Dictyostelium p...
XP_003386213  83 --------qeeESYTEEQLKIMKTQ-DLKYVQLKLSTEKSKIDRLRASLHQTEEREkh---------------------- 131 Amphimedon quee...
CDS43510      86 --------nntKEYSDSELVDMLSC-DILYLRREFTIEMSKIRELESRFNLLPADPSvasrr------------------ 138 Echinococcus mu...
XP_004035419  89 EDFDK----------NEFKSLVKAK-NMNLIKVQKHKDMKQIQKLQAQLHNLEGPKMn---------------------- 135 Ichthyophthiriu...
XP_001021316  89 FD------------PKEYRRLLKNQ-NINLIKIQKHKDMKQIEKLKSQLHDLDAPRQn---------------------- 133 Tetrahymena the...
EFC45750      93 KKKEAlnnlkkTKKEQRLFVQQNAEkNLNLLRMKLQIINNNIEKLRRGLGFLEVASKsdk-------------------- 152 Naegleria gruberi
Q5CT03        87 G----------GLTSAEERKLAESQ-NLTYVHFRKSIDNKKIERMEKELTLFGQNMQr---------------------- 133 Cryptosporidium...
EGF97666     152 isaankeddgsaeednstlsasgkKTIFVDSVEE-VRNFEQIRNKKRKSSISSSqrnlpiaststshsstrsvkhksgst 230 Melampsora lari...
EFA76319     131 -----------------------dQVIFLDNENE-VKNFNAVEYFETIPEAFSNns------------------------ 162 Heterostelium a...
Q55C50       132 -----------------------eQIIYVDDEKE-VKNFSATKYFDTVPDAFNGsl------------------------ 163 Dictyostelium d...
EGC38956     131 -----------------------eQVIYLDNEKD-VKNFSATKYFDTVPEAFDGsl------------------------ 162 Dictyostelium p...
XP_003386213 132 ----------------------ntHLIFVDDEDE-ADSEEELESRENETSTAGEddmdddddd----------------- 171 Amphimedon quee...
CDS43510     139 --------------------lkpkRTVFVESIEEaRAVRSSFDPSAVSIQIPGSvpa----------------------- 175 Echinococcus mu...
XP_004035419 136 -----------------------qQKYFVDSKEE-FDNFQIEKDNQILNQPENLvfifk--------------------- 170 Ichthyophthiriu...
XP_001021316 134 -----------------------tNIIFVDDKEE-YENFDLVEHYNTTEEMIQNksni---------------------- 167 Tetrahymena the...
EFC45750     153 ---------------------kikHKVFLKSKEE-LETFDPVEYFDTDPLLLN--------------------------- 183 Naegleria gruberi
Q5CT03       134 -----------------------sHIFFDDEHEQ-LESGSQK-------------------------------------- 151 Cryptosporidium...
EGF97666     231 stndtetdlaeqkLEADRHMRK--------------------------------LLGNLKSRLTRLRTLQKAERELEL-- 276 Melampsora lari...
EFA76319     163 ------------sTIPKLSKLKegslvlnprtap---------saaeieamtttSYKELEARKIRHAELYKAERQLEH-- 219 Heterostelium a...
Q55C50       164 ------------sTIPKISKLKegslvvnpktap---------tlgqleamtatSYKELKERKLRRDQLFKAEMDL---- 218 Dictyostelium d...
EGC38956     163 ------------sTIPKLSKLKegslivnkktap---------algelesmtttAYKELNERKHRRDQLFKAETEL---- 217 Dictyostelium p...
XP_003386213 172 -----dfqfkdlsIRVRKRSRKepipgd--------------------apdaegRYKELESRLKRCQELKMLSERMQL-- 224 Amphimedon quee...
CDS43510     176 ----------sdaDALMDLQAA--------------------------------GYKELSKRLIRAEKLKLAIAKREA-- 211 Echinococcus mu...
XP_004035419 171 --------kifiqLFIFQQRNRrnh--------------------------ykeKLKNLIKNLKKYKRIMKKWKKHILnw 216 Ichthyophthiriu...
XP_001021316 168 ----------ltkQQIEQQKEQleqlnskq-----------------inqkvkeSYMKLKKVEENHKKMERAYQKLEF-- 218 Tetrahymena the...
EFC45750     184 ---------------QTHNRVKrktlaeqsvqayapnagidayttpatdnatlaEYKKLEKLISKREVIEKTINDIEV-- 246 Naegleria gruberi
Q5CT03       152 ---------------NKSNSKKlkdldslsnlet---------ipkevvknitkSYKIFNDTIARSQKLEKVSKHLEL-- 205 Cryptosporidium...
EGF97666     277 ------KRAL-M--GNGskfLKnsvqkkkalpsgRDLSWyDKldrndlieeqdekerlaklnegiktgatvwKWKAERKR 347 Melampsora lari...
EFA76319     220 ------QKQSiK--NKGekpIK------------VKVGGkKE------------------------------TWKLKRKK 249 Heterostelium a...
Q55C50       219 ------SKSK-IqlKRGtksGV------------TKKVGkKEv-----------------------------VFKQVRSK 250 Dictyostelium d...
EGC38956     218 ------AKSK-IqlKRGnssGV------------SKKVGkKEv-----------------------------VFKQVRSk 249 Dictyostelium p...
XP_003386213 225 ------QKHL-L--NKK----E------------KRVKE-RGggr------------------------tiyKWLPERKR 254 Amphimedon quee...
CDS43510     212 ------KATL-MrsAN----VK------------YKVIRkGNsnha-----------------------pvyKFE-QRRY 244 Echinococcus mu...
XP_004035419 217 iikkicQQYL-SiyLKYknqQK------------KEKRRiRKykng-----------------------evaKFFRERKR 260 Ichthyophthiriu...
XP_001021316 219 ------EKNLlG----------------------KEKRRiKKyktg-----------------------kvaKFFSERKK 247 Tetrahymena the...
EFC45750     247 ------ALQLtLssDKVekiER------------DKSTErKNlkgdys-------------------dvktvQFKKERKR 289 Naegleria gruberi
Q5CT03       206 ------QRDL-----KSkgkKK------------KVVTKnGNte---------------------------yVWYPKRKK 235 Cryptosporidium...
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