1TWH,5X50


Conserved Protein Domain Family
RNA_pol_Rpb8

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pfam03870: RNA_pol_Rpb8 
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RNA polymerase Rpb8
Rpb8 is a subunit common to the three yeast RNA polymerases, pol I, II and III. Rpb8 interacts with the largest subunit Rpb1, and with Rpb3 and Rpb11, two smaller subunits.
Statistics
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PSSM-Id: 397790
Aligned: 113 rows
Threshold Bit Score: 129.144
Threshold Setting Gi: 89288126
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1TWH_H                         10 FQVSEVDP--GRYNKVCRIEAASTTqdQCKLTLDINVELFPVAAQDSLTVTIASSLNLE----------DTpa--nDssa 75  baker's yeast...
CCX08268                       12 FRITAVND--VKYDRVARIFGERD---DLKFSLDINSEIYPVFVDETVQLSIASTLNLD----------GSivskeSaaa 76  Pyronema omphalodes CBS 100304...
CAZ80545                       41 FPITGFDQ--NKYDRVARISGERE---DLKFSLDIHVELYPVAIGETVQLSLASTLSPD----------GAke--dPaes 103 Perigord truffle...
XP_004997195                    8 FTVKAKDPkgRKFERVSRIVCEAFMt-GFELILDLNTQLYPMELDEQFSLCLARSLDDE----------AAp---sSgty 73  Salpingoeca rosetta...
WGS:AAGF:cds.TTHERM_00549610A  12 FKLEEIKKeeK-FSKVERVVLVSDN--NIKIEIDIHTDLYSMKKGNQYWVMITSSLGNFqedkgifvseEF--------- 79  Tetrahymena thermophila SB210...
A0DFX5                         13 FKVEDIDQagQSFKRVSRIKCKSKSg-EVDMELDVNIDIYPIDKGSEYRVLIVRSLGISqemd---------qgkyKpef 82  Paramecium tetraurelia...
XP_656855                       8 FKVIAKDIggKIFEGVSRFKLEGE---DLTVFVDINTDLFPLEEHDRIKLDLTKTLNRD----------GSpmdihQgys 74  Entamoeba histolytica HM-1:IMSS...
XP_015785465                   11 FDVLDVNCdtSVAENVNRIHCEGIEt-QTDLLLDLYSPVFNVKKGEKINVLLVKEIQSGkrklenddsdMEvyd------ 83  two-spotted spider mite...
Q384M6                         12 FTVAAVNEegTVYSRVSRVRCTGEGg-GLIITSDVNTGEFPLHSGDRLTIILTDSIELS-----------------Eqag 73  Trypanosoma brucei...
Q4DCA7                         12 FTVTALNPdgVVYIKVSRIQCKNERg-NITITSDINTEEFPVSLDDRLTIMLANSIELS-----------------Gqsg 73  Trypanosoma cruzi...
1TWH_H                         76 trs-wrppqAGDRSLAD------------DYDYVMYGTAYKFEEVSK----DLIAVYYSFGGLLMRLEGNYRNLNNL--K 136 baker's yeast...
CCX08268                       77 kggwrdvgaAGEVTLAD------------QYDYVVYGKMYRFEEGSG----ETIKVYASFGGLLLFIEGPHKRLSSF--K 138 Pyronema omphalodes CBS 100304...
CAZ80545                      104 ktg-wkenkAAEPSLAD------------TYDYVCHGKVYRFEEGNG----EFIKVYASFGGLLLFLEGPHKKLSSM--R 164 Perigord truffle...
XP_004997195                   74 -------vqnRESSLAD------------SFDYVMHGTIYRVEEKE-----GQVAVYASYGGMLMRLKGNRSALMKPglE 129 Salpingoeca rosetta...
WGS:AAGF:cds.TTHERM_00549610A  80 ----------DRESIKD------------KFEYVMHGKIYNMNSDNKa---KTVSIFASFGGLLMKVSGKDEDLKNF--N 132 Tetrahymena thermophila SB210...
A0DFX5                         83 --------sqIDNELLE------------KFQYAMFGRVFKMIKDQN----KMINVFASFGGLILKLSGKSEELDKF--A 136 Paramecium tetraurelia...
XP_656855                      75 -------dnfGKNTKMD------------DFDYVMSGMVFKFVENKNd---DNLSVIASFGGLLLMLYGKPEKLSAY--N 130 Entamoeba histolytica HM-1:IMSS...
XP_015785465                   84 --------anGQSSTVDpldtssilneysKFKYIMHGKIYKIENKMIstnePIIAVYASFGGLLFRLQTSLENHSDW--H 153 two-spotted spider mite...
Q384M6                         74 skh-ydqsvYHRSTRLD------------DCDYAMHGRVYSMEVNESs---LDVTVHISCGGLLTQIVGKPQSLKDV--H 135 Trypanosoma brucei...
Q4DCA7                         74 akh-ydqsvYHRETRLQ------------DCDYAMHGRVYGHEVDESs---LDVKVHISCGGLLTQVIGTPQSLRDI--H 135 Trypanosoma cruzi...
1TWH_H                        137 QE-NAYLLIR 145 baker's yeast
CCX08268                      139 HE-YIYLLMK 147 Pyronema omphalodes CBS 100304
CAZ80545                      165 HE-YVYLLMK 173 Perigord truffle
XP_004997195                  130 LDsSLYLLIR 139 Salpingoeca rosetta
WGS:AAGF:cds.TTHERM_00549610A 133 VDsRIYILIR 142 Tetrahymena thermophila SB210
A0DFX5                        137 DDqRVYLLMR 146 Paramecium tetraurelia
XP_656855                     131 MKdQVYLLIR 140 Entamoeba histolytica HM-1:IMSS
XP_015785465                  154 IDrNLYLLIR 163 two-spotted spider mite
Q384M6                        136 YNsDVYILMK 145 Trypanosoma brucei
Q4DCA7                        136 YNsDVYILIK 145 Trypanosoma cruzi
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