Conserved Protein Domain Family
TerC

?
pfam03741: TerC 
Integral membrane protein TerC family
This family contains a number of integral membrane proteins that also contains the TerC protein. TerC has been implicated in resistance to tellurium. This protein may be involved in efflux of tellurium ions. The tellurite-resistant Escherichia coli strain KL53 was found during testing of the group of clinical isolates for antibiotics and heavy metal ion resistance. Determinant of the tellurite resistance of the strain was located on a large conjugative plasmid. Analyses showed, the genes terB, terC, terD and terE are essential for conservation of the resistance. The members of the family contain a number of conserved aspartates that could be involved in binding to metal ions.
Statistics
?
PSSM-Id: 397694
Aligned: 70 rows
Threshold Bit Score: 111.802
Threshold Setting Gi: 123493360
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q7URC1          43 FALTLMEIVLGIDNIVFIAILTGKLPAE-KRSFARRFGLFVAMGMRILLLMMIGWLMSLqspiielsslapieslrehla 121 Pirellula sp.
WP_011745600    20 LNLVLIESLLSVDNAAVLATMVMDLPPK-ERSAALKYGIIGAYLFRGLCLLFAAFLVKI--------------------- 77  Chlorobium ph...
tigr:GBAA_0402  34 gTLVVLEGLLSADNALVLAVMVKHLPEE-KRKKALFYGLIGAYVFRFIAIGIGMFLIKL--------------------- 91  Bacillus anth...
Q03PL0          32 FSLVLIECLLSVDNAVVLAAQTQSLPTReQQEKSLFYGIWGAYFFRFVIIGLGTYLIHF--------------------- 90  Lactobacillus...
jgi:Dgeo_2235   20 LTLAVLEGLLSADNALVMAVMVRPLPAR-LQQKALTYVMWGAMGLRLVGVLLASFIIKY--------------------- 77  Deinococcus g...
jgi:Exig_0231   14 LVLIILQGLLSADNAMVMAVLVRPLPDD-QRKKALFYGLIGALVLRFVAIFFASYLATI--------------------- 71  Exiguobacteri...
Q8Y8B7          14 lVLIGLEGILAADNAVVMAVMVKHLPDK-QQKKALFYGLMGAFVFRFGALFLISFLANV--------------------- 71  Listeria mono...
Q2JMI0          24 VALVFLEAALSADNAVALAALVKHLPTPqQQNRALRWGIIGAYSFRIAIVFAAVWLVEY--------------------- 82  Synechococcus...
Q7NMY8          24 FALVFVEGALSADNAAVLAALTRTLPTDeERRRSLRYGIIGAFVFRFFAVLFAAWLIDN--------------------- 82  Gloeobacter v...
Q3A0T7          25 GTLAILEGILSVDNALVLAILVRNLPRQ-QQKRALTYGIIGAFVFRFIALVFAAHLMRF--------------------- 82  Pelobacter ca...
Q7URC1         122 adaevneisgrDLILLFGGLFLMFTAVREIHHKIegehdddpqmdMDLPEADAAVKSRKPVT---------------VGS 186 Pirellula sp.
WP_011745600    78 -----------WWLKPLGGIYLLYLVWNWIk-------------gKKTVETKDDYFDKQDNWfykhtv----gslgvFWS 129 Chlorobium ph...
tigr:GBAA_0402  92 -----------AWVKVLGALYLAWLSVKYFIDKRkg-----------nAEEEEAHGMNQNSIlfrm--------fgvFWG 141 Bacillus anth...
Q03PL0          91 -----------WEIKVIGALYLLYLVFQFF---------------TRTRVKHTRKLASEKKHrwl----------plFWA 134 Lactobacillus...
jgi:Dgeo_2235   78 -----------WFLRAFGAAYLAYLVISHF---------------VKKGRDEEGGPKELSGN---------------FWN 116 Deinococcus g...
jgi:Exig_0231   72 -----------WELQALGAIYLFYVAFKGIVEARs----------NKHQIPESASAKKASPN---------------FWW 115 Exiguobacteri...
Q8Y8B7          72 -----------WQVQALGAAYLLYIAISHIWKH------------AKGKDGEKEKKEKAGSG---------------FWM 113 Listeria mono...
Q2JMI0          83 -----------PPAQFLGACYLLWLAWQHF----------------RGEEEGQEQDITRHAN---------------FWQ 120 Synechococcus...
Q7NMY8          83 -----------WPLKLAGALYLIYLAVSHFL---------------KGKDEDEDVVAEEKKLlsnplfratlgrlspFWR 136 Gloeobacter v...
Q3A0T7          83 -----------GFFKLIGGGYLIYLAMKHMFFFY--------------KEDAHQLRDKPAAG---------------FWK 122 Pelobacter ca...
Q7URC1         187 VLFQIAVMDVIFSLDSVITAVGMA----------------SHLPIMIAAVVISVGVMITFANQISDFVQEHPTVKMLALS 250 Pirellula sp.
WP_011745600   130 TVILIELMDLAFSIDNIFAAVAFT----------------DNIILIWFGVFIGILAMRFVAQGFVRLMELYPFLETCAFI 193 Chlorobium ph...
tigr:GBAA_0402 142 TVAMVELMDIAFSVDSVLAAFGVS----------------NEVWILLLGGMLGILMMRGIAGVFLKLLERIPELETTAYI 205 Bacillus anth...
Q03PL0         135 VVLQIEMMDIIFSVDSVLASLAIS----------------SNPVIVLIGGLIGILAMRGVAEVIMRLMQKIPELEPMAYI 198 Lactobacillus...
jgi:Dgeo_2235  117 VVISLNLVNLAFSVDSILAGVALLkpem--------rdtaAGFWIVVAGGLMGLVLVRFASTFFLKLLDRFPALDDVAYI 188 Deinococcus g...
jgi:Exig_0231  116 TVVKVEFSDLAFAVDSTLAAVAMAttlpmigg-tigglntGQFWVVFFSGIIGLVIMRYFASWFVVLLQKRPGIEEAAFW 194 Exiguobacteri...
Q8Y8B7         114 TVLKVEIADIAFAIDSMLAAVALAitlpetgwghiggidtGQFAIMFLGGLVGLIIIRFAATQFVKLLKSYPSLETAAFL 193 Listeria mono...
Q2JMI0         121 TLVMVELTDLVFSFDSIAASVGVS----------------RKAWVIILGGILGITLMRYMASLFLRWLDEFSHLEDAAFA 184 Synechococcus...
Q7NMY8         137 VIVLVELTDIAFSVDSITAAVAFS----------------DKAWVVIVGGILGIVTMRFVAELFIKLIDRYVRLETAAFL 200 Gloeobacter v...
Q3A0T7         123 IVIMVELTDIAFSIDSITTAVAMT----------------DKLLVVWVGGILGIIFLRFAASFFVRLLERLPRLEDLAYQ 186 Pelobacter ca...
Q7URC1         251 FLILISVVL---LSE 262 Pirellula sp.
WP_011745600   194 VIGVLGVKLsvsVFE 208 Chlorobium phaeobacteroides
tigr:GBAA_0402 206 LILIIAAKM---LLs 217 Bacillus anthracis str. 'Ames Ancestor'
Q03PL0         199 LIALIAVKL---FIS 210 Lactobacillus brevis ATCC 367
jgi:Dgeo_2235  189 LIGWIAIKLgieTVE 203 Deinococcus geothermalis DSM 11300
jgi:Exig_0231  195 LVAWVGVKL---VVM 206 Exiguobacterium sibiricum 255-15
Q8Y8B7         194 IVGWVGVKL---VIy 205 Listeria monocytogenes
Q2JMI0         185 IIALVGSTM---LLE 196 Synechococcus sp. JA-2-3B'a(2-13)
Q7NMY8         201 AVGFIGFKM---MTE 212 Gloeobacter violaceus
Q3A0T7         187 LIFFIGTKL---FLD 198 Pelobacter carbinolicus DSM 2380
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap