Conserved Protein Domain Family
UPF0160

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pfam03690: UPF0160 
Uncharacterized protein family (UPF0160)
This family of proteins contains a large number of metal binding residues. The patterns are suggestive of a phosphoesterase function. The conserved DHH motif may mean this family is related to pfam01368.
Statistics
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PSSM-Id: 397652
Aligned: 188 rows
Threshold Bit Score: 219.689
Threshold Setting Gi: 524123688
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4CZB7                32 VIGTHNGSFHCDEAMACGLLRCSqnFGQSN-------ILRSRDPNALERCN------IVVDVGSVYDEATLRFDHHQPSF 98  Trypano...
CDE55395              12 nLITHGGVFHADDVMATVILEKV--FGDVT-------VCRVL--EVPEKLNsn---vIVYDIGG------GKWDHHQKGG 71  Clostri...
CCZ00287              28 fCITHGGRFHADDLFAAAIMLLV--FSFTEpenetfkVARALTTDDISNANg-----VTFDIGG------GEFDHHQKGG 94  Clostri...
CDA59350              12 nCVTHGGKFHSDEIFATVILSKI--LTNIK-------LIRVN--EVTDSMResiankLVYDIGG------GEFDHHQAGG 74  Clostri...
WP_012651973           5 fLVTHSGGFHADELLSSVILTRL--FPQAR-------IIRSRAPEWITPGAd----rIIYDVGGKYDAAERIYDHHQRG- 70  Agrobac...
WP_020950993           5 yLVTHNGGFHADELFSSVILTRL--FPDAQ-------LVRSRSPEWITPAAd----rVIYDVGGAYDAEAGIFDHHQRG- 70  Paracoc...
ADO44348               5 yLVTHSGSFHADELMSSVVLTRL--FPDAT-------ILRTRDAQAITPADd----rIIYDVGRAYDADQRIFDHHQPD- 70  Ketogul...
Q1GEB6                 5 HLVTHSGGFHADELLSTVILSRL--YPHAE-------LVRTRDKAWITPAEg----rIIYDVGGQFDAAARIFDHHQRP- 70  Ruegeri...
goetting:PGA1_c26080   5 HLVTHSGGFHADELLSSVILTRL--FPDAE-------LIRSRDAAWITPAAg----rIIYDVGQAYDGEAQIFDHHQRP- 70  Phaeoba...
WP_012810734           2 KIGTHHGKFHADEVFAVAILRKL--YPDAR-------IVRTRNKSVLAQCD------LVVDVGG------GPYDHHSVQ- 59  Alicycl...
Q4CZB7                99 HDTMKTPkaaYQTRLSSAGLVYKHFGREIIQGY--VEsalaspyrvklldatkwgtdkkklSEQELDILFDIVYKNFVEH 176 Trypano...
CDE55395              72 NGARKNGs-kIGVPYAAAGLIWRDFGYEAIKKHf---------------------------PNTNLYEVWNSVDKMLIQG 123 Clostri...
CCZ00287              95 NGYHSNG-----VPYAAFGLIFRRFGKDVISKVvnST------------------------DTNIINPIFDRLENSIVST 145 Clostri...
CDA59350              75 NGQRDNG-----VKYASCGLIWKSYGKKYLEKCn--------------------------vKKEHIEELCLQIDKDLIQY 123 Clostri...
WP_012651973          71 APLRDDG-----QPYSSFGLIWKHYGRDYLSASg--------------------------lPEAHIEALHTSFDNGFVLP 119 Agrobac...
WP_020950993          71 APLRDDG-----QPLSSFGLIWRHFGRDYLAASg--------------------------vPADHIETVHASFDAGFVLP 119 Paracoc...
ADO44348              71 APRREDD-----QPYSSFGLIWKHFGADYLRAMa--------------------------vPEGDIEAIHLSMDRHFALP 119 Ketogul...
Q1GEB6                71 NPLRPDG-----QPYSSFGLIWAAFGQDYLRALe--------------------------vPEKDLDRVHAAFDADFVRP 119 Ruegeri...
goetting:PGA1_c26080  71 NPLREDG-----QPYSSFGLIWHHFGRDYLRGLd--------------------------vPEADVDAIHHGFDQSFVLP 119 Phaeoba...
WP_012810734          60 KVHRPNG-----IPYAAAGLIWRDFGDRFLEALgvE-------------------------REEDRALVSSNIDDKLFQA 109 Alicycl...
Q4CZB7               177 IDGIDNGVN-AYGPaetegeegavpvsssspsCVKKYNVST-TLSARIGNLMPWWNEegnGKVENENAAFLQAMELATSE 254 Trypano...
CDE55395             124 IDATDNGVN-----------------------NTSSQEVAAmSICQMISNYNPTWDD-----ETDYDEAFLNACNIAREI 175 Clostri...
CCZ00287             146 VDACDNGESgVDSRky--------------hiVSMSEYISArYMSCEITRHNL--------TNDDYNEQFLFALEEVTTY 203 Clostri...
CDA59350             124 IDANDNGQS-----------------------TKIDTDYKLvELASVISAFNPCWNE-----TVDTDECFMQAYEIVKKY 175 Clostri...
WP_012651973         120 VDLVDNGALs---------------------pSVAGQL-AGlTLPALLETLKPVFDE---TDPEAEDRGFQNALGIARSF 174 Agrobac...
WP_020950993         120 IDLVDNGALs---------------------pASAGPLLTGmVLPSLMETLKPVFDD---TDPGSEDRAFQTALTIARAF 175 Paracoc...
ADO44348             120 VDLVDNGALd---------------------pATAGAL-VGlTLPVLLESLKPVFDN---DDPAAEDQAFHAALAIARAF 174 Ketogul...
Q1GEB6               120 VDLLDNGAVd---------------------sAEAGPLFAGlTLPVLLESLKPVFDD---RRDGADDAAFVDALAIARAF 175 Ruegeri...
goetting:PGA1_c26080 120 VDLLDNGAId---------------------pGVAGPL-AGmTLPVLLETLKPVFDD---RRDGADDQAFLAALPVARAF 174 Phaeoba...
WP_012810734         110 IDAIDNGID-------------------------LERDMRIkGISELVGSFNPPWNS-----QEDENRAFERALDFATQI 159 Alicycl...
Q4CZB7               255 FFDSVHYhVFAWMPARGIVRAAFLEAmnvhPSGRIVVFKDCfCPWKEHLL-EL---EEEHGkvgHVLYVLF-AdKKGWRV 329 Trypano...
CDE55395             176 LWNIVKK-SVSTCKAKKFVKEAIEQ-----SSDHIMVLQRF-VPWQRYLYlST---NPKAM---DIWFVIYpSlRGGYNW 242 Clostri...
CCZ00287             204 LVITIKK-EFHLIQGDQKVVKLLND-----SDDNILVLDDD-LPYRNALI-NHpkgS-------SIQLVIKpSiRGGFQL 268 Clostri...
CDA59350             176 FERFIAR-EIAKNEAKELVENAIEN-----SKEGIMILEQF-MPWEEAVLtST---NPKAE---KINFVVFpSnRGGFCV 242 Clostri...
WP_012651973         175 VEARIGQ-SAAKLRAEALVHQAIVET----GEGRILELPMG-MPFRPAIV------KAGAD---HLLFVVHp-rDKDWCL 238 Agrobac...
WP_020950993         176 VEARIAR-SAAKLRAEGMVFDAIARA----GESRILELPMG-MPFRPTVV------KAGAD---HLWFVINp-rGKDWGI 239 Paracoc...
ADO44348             175 FEASVGR-KAAKARAESMVLDAIATA----GEGKVLELPRG-MPFRSAID------QAGAD---HLLFVITp-rGTDWSL 238 Ketogul...
Q1GEB6               176 VEARLRH-KAAKLRATDVVLRAIEDA----GERRVLELPMG-MPFRGAVE------QAGAD---HLLFVIHp-rDSDWAL 239 Ruegeri...
goetting:PGA1_c26080 175 VEASIRG-KAAKRRAETMVLEAIEGA----GAGKVLELPMG-MPFRSAVE------KAGAD---HLLFVVHp-rGSDWTL 238 Phaeoba...
WP_012810734         160 LMNYANH-EISRLQATEIVKAAYAAR----KEPALLVLPTC-CPWTETLL-EIdpaG-------EVLYVAFpDkTGQYRL 225 Alicycl...
Q4CZB7               330 QAVPK----EA-SGFENRKSLP--WRGLRDEELSQASGIEGGIFVHVSGFIGGNKTYEGALQMAVKAL 390 Trypanosoma cruzi
CDE55395             243 QTVTT----DL-KKRIPMKPVPeeWCGLKGKELQKITGVNTAIFCHDGGFVGSAETIQDAIKMAQLAI 305 Clostridium sp. CAG...
CCZ00287             269 CSIPKigvkTPnDSFK--VAFPqeWSGESGHKLQELTHCGSAIFCSNDRRFLVCETKEGALELARNLL 334 Clostridium sp. CAG...
CDA59350             243 HTVPK----EL-GSFENRKSLPkeWAGLRDEKLQEVSKIKTAKFCHNACFICTAETREDAIKMAEIAq 305 Clostridium sp. CAG...
WP_012651973         239 TGIRR----AD-QGFELRADLPaaWAGLTNGDLEAASGVEGASFCHNGRFIAAAKTREAALAMAELAV 301 Agrobacterium
WP_020950993         240 GGIRK----SE-DGFELRADLPasWAGLSGEALEAASGVPGALFCHNGRFIAAAATREAAVAMAEIAV 302 Paracoccus aminophilus
ADO44348             239 AGIRK----KP-DGFEQRADLPaaWAGLNDAALEAASGVKGAKFCHNGRFIAVADSREAIVAMAEIAV 301 Ketogulonicigenium ...
Q1GEB6               240 TTIRT----GD-DTFETRADLPlaWAGLTDAAFEAASGVPGAAFCHNGRFLAIARSREAVLALAELAV 302 Ruegeria sp. TM1040
goetting:PGA1_c26080 239 TTIRK----SG-DSFESRADLPaaWAGLMDEALEAASGVAGAKFCHNARFIAVARTREAIMDLANRAV 301 Phaeobacter inhiben...
WP_012810734         226 QVVPK----GP-GTFEARKPLPseWAGKEGEELVSICGVEDAVFCHPARFIAGAESLDGILQMAEEAL 288 Alicyclobacillus ac...
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