5AGD,4C1S


Conserved Protein Domain Family
Glyco_hydro_76

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pfam03663: Glyco_hydro_76 
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Glycosyl hydrolase family 76
Family of alpha-1,6-mannanases.
Statistics
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PSSM-Id: 397638
Aligned: 87 rows
Threshold Bit Score: 149.384
Threshold Setting Gi: 118568118
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5AGD_A         23 YTASDGDTAMKAFNdTFWDPNakM--FW---KDSKRE-----KHQ---------DF------WVEAELWELVMDAYQHTS 77   Bacillus circ...
ABN64243       46 SASAVPVNAFQDTVdDIWNRFwsE--PNaawSDNDNIcgstsFAPl--------VV------WDQAVVGTAIVNTLN--- 106  Scheffersomyc...
O14131          6 YLNEALNVVDQCFK-TFFDKYtdR--MGsafACSGTI-----DKDhi------fLV------WSVAVYAEAMADSLRYTS 65   Schizosacchar...
Q6CGF0          9 TNAEGLSIVEKAQK-TFFNRG--T--YSsnpPCDGCY-----DDKgt------fCV------WPVAVFAQAVVDGARIYP 66   Yarrowia lipo...
WP_005361619  199 FTEAMADKALEAFKnKYYVKN--S--TTgydSLGGGF-------------------------WGIAEVMEAMLDGYETTG 249  Eubacterium v...
WP_005824849   34 DWDAAADSSSVTLIdRFWNTE--E--NYfnyGNDGSI-----KDF---------HY------WPQAHAMDVMIDAYNRTG 89   Bacteroides
EAQ78697       24 QYAERAEEVTGFIQkNFFDAQ-----SGvyfKTVKHD-----RLD---------YV------WLQSVMFANLTAAARIEP 78   Blastopirellu...
4C1S_A          2 hMADRAHSYMTSVI-GYYFGK-----SS---RSCWRS-----NYPydg----kgYWdgdalvWGQGGGLSAFVAMRDATK 63   Bacteroides t...
WP_012186052   33 ELYSKRAVATFNALqDHYYVNslNlyKG---STCGDY-----SCL-----------------WTYSQILSALVYLSLTPG 87   Caldivirga ma...
Q9S1S4         40 TWADRATGTYRALQkHLYEGP----------GDHGLYl---eHTPrqatdqehsYL------WPFREAAQAAVDMQRLPR 100  Streptomyces ...
5AGD_A         78 --DPalkaelkTQIDDVYD---GTVA----KYG---QD---------WTN--NP-FND--NIMW--WAMGSARAYQI--- 126  Bacillus circ...
ABN64243      107 --KP-------RIDATLTN---LLQY----KNN---ENgafs--attAGD--DDiYNDdnAQAA--WVF--IDAYKA--- 156  Scheffersomyc...
O14131         66 -----------KFERKFEHvfqALKK----YWS---PVfnac-cafhYFE-----GND--DVYYddNAQVAIGLATAgyy 119  Schizosacchar...
Q6CGF0         67 -----------ELKKLIPQ---AFEA----FKP---YEtqey-psvcTASkyFD-GNK--DIYF--DDNAQIASAYItay 119  Yarrowia lipo...
WP_005361619  250 --KP-------IYRDMFQN-----------------TYkdfi--arnGDY--WS-NNDfnDDIA--WAVLDSVRAYLlfg 296  Eubacterium v...
WP_005824849   90 --DS-------KYSDLFDKwyvGIKA----KNGgs-----------yWNN-----FYD--DMEW--IALTMIRLYEV--- 133  Bacteroides
EAQ78697       79 --DKyalpldaYFTAL------DGYW----DAKakiPGyeaa--ptrGNG--NDkYYD--DNAW--LVITFLEAYETnhd 138  Blastopirellu...
4C1S_A         64 --ESevenlygAMDDMMFK---GIQYfcqlDRG---ILayscypaagNER-----FYD--DNVW--IGLDMVDWYTe--- 123  Bacteroides t...
WP_012186052   88 --LG-------NFTNLFNQyylGLSH----YSNplnPSsgye--savTPPigPG-GDTyyDDNE--WVTLALIKMYLa-- 147  Caldivirga ma...
Q9S1S4        101 tgPA-------YRQDAAERfdtAELY----HTGgerPGyrsy-lpapLGTggDV-YYD--DNAV--VALSQLDQYEe--- 160  Streptomyces ...
5AGD_A        127 ----TGNPRYLEAARDHFDFVYDTqWDEEF---ANGGIWWLN----SDHNTKNACINFPAAQAALYLYDIT---KDEH-Y 191  Bacillus circ...
ABN64243      157 ----TGNTDYLDNAKGIVNWVISQ-W---A---SNGGVFWHL-----NNNYVASISTTEAALAAVRLYEIE---QDNK-L 216  Scheffersomyc...
O14131        120 ttnsSRRDHYVSRAESIISLIINKgWNQQR-----GGIAWHTrttgPPWTNLNACSTSMSAVAALRLALALddpNKKQhL 194  Schizosacchar...
Q6CGF0        120 --evTGEKSFLDKGRNIVRFLMTG-YDSTG---EPGGVRWHI-----GKTGSNACTTSESACAALRLSKYVp--NEASyY 186  Yarrowia lipo...
WP_005361619  297 ------dqSYLDIAKKNWDFMYKR-GTEGR---TDGLIRWsh--enGRGDGTTSCINGPATVGACYLAIAT---GDDS-Y 360  Eubacterium v...
WP_005824849  134 ----TDENKYLETSQEMWNEIKTG-WNDY----AGGGIAWTHdql----wsKNACSNGPAALIAARLYRIN---GNQE-D 196  Bacteroides
EAQ78697      139 -------prYLQRADETQRFVLSG-WDEE----IGGGIWWHErh-kDG--TKNTCANGPAAVGCLQLAKFEt--AEAPaL 201  Blastopirellu...
4C1S_A        124 ----TKEMRYLTQAKVVWRYLIDHgWDET----CGGGVHWREl--nEHTTSKHSCSTGPTAVMGCKMYLAT---QEQE-Y 189  Bacteroides t...
WP_012186052  148 ----TNNTRYLRRAEELFNFIISG-WSTNEslrCPGGIYWRV-----GDLSRNTVSNSPAAEAAAELYLIT---GNPS-Y 213  Caldivirga ma...
Q9S1S4        161 ----TGDARYLRRAEQVVPVVSRA-WDGDAakaCPGGMDWyd---aPGNTIRATNVTALSAQLAARLYEHT---RNRA-Y 228  Streptomyces ...
5AGD_A        192 LNAATKIFR-WGKT--MLt--DGNGKVFDRI-E---IEHGA----VPDATH-YNQGTYIGSAVGLYKATGNAVYL-DDAV 256  Bacillus circ...
ABN64243      217 LEFASNCMD-WMFAn-LQd--KSDYLFYDGL-----NNDDYs--dINKGKLtYSVGCGLSAMAYLHYYTGNQKWL-IESK 284  Scheffersomyc...
O14131        195 VSFAWNCVR-WIQEn-LL---DENHIVCDGL-S---LKDGKw--vLDKARFtYNTGTTMTAMSLLMGLG-------EFTK 256  Schizosacchar...
Q6CGF0        187 IDFARDCVK-WVVHr-LQd--PEDWLIRDGVeY---HDGQGf--sVNDMKWtYNQGTTISALSGLYGITND-QWYlKEAE 256  Yarrowia lipo...
WP_005361619  361 YTKAKSVFDaWRNSslYVregDDAGHVWDSA--------------GNNWRStYNQGTFLGAAIMLYEKYGTQQYY-DDAC 425  Eubacterium v...
WP_005824849  197 LDWAVNIYK-WEREn-LFn--PATGAIYDN------VNGETg--eLSTLSLsYNQGTFLGAAYELYKITGEESYL-KDAR 263  Bacteroides
EAQ78697      202 IQKAREIVA-WTNSal----qDDDGLFDDRK-----VVATg---eIKRGKLtYNSALMLRANLGLYRATGESAYL-DEAK 267  Blastopirellu...
4C1S_A        190 LDWAIKCYD-YMLDvlQd---KSDHLFYDNV-RpnkDDPNLpg-dLEKNKYsYNSGQPLQAACLLYKITGEQKYL-DEAY 262  Bacteroides t...
WP_012186052  214 LKWAIRILN-WVNQ--CLr--SPSGLYYDHI-----NPDGT----IDETIWsYNQGTTAAAAALIYEATHNESYL-VLAE 278  Caldivirga ma...
Q9S1S4        229 LDKAEQWYG-WVYAc---------MRKAPGL-Y---VNDRGddgsTNETLWtYNSGAMIGTATALYRGTGDARYL-EKAV 293  Streptomyces ...
5AGD_A        257 KAAKFT--KNHLVDSn-------GVLNYE---GPNGDLKGGKTILMRNLAH-LQKTl-dETGQYP-EFSAEFDEW---LA 318  Bacillus circ...
ABN64243      285 NIATSVtkGSGAFYG-------------------SDGAWNNQLQYVHLLFM-GFAD---LFKYIP-WQPEFDGYKtevLK 340  Scheffersomyc...
O14131        257 GLQDIEk-LPTYLEDmargaldtNGPLYDqscNGSFKVWSDNTFFAQHLSE-GLMT---FSYAMP-SSA---------LA 321  Schizosacchar...
Q6CGF0        257 KIIRGV------CDP--------NTTIFDrdtQPEFRYYRDNVYFYQLLAE---GF---ADFLL--FCGDDTDPK---YA 311  Yarrowia lipo...
WP_005361619  426 NVMANT--VKHLCYN---------NILKEen-----tNSGDLSGMRGILMR-YM-----RKFIVD-FNKGEYLSF---FK 479  Eubacterium v...
WP_005824849  264 KAANFAisNSSMIDTg-------NNLLRD---EG----DGDGGLFKGIFMR-YYVQlimEPNLDP-IYKKKFITF---FN 324  Bacteroides
EAQ78697      268 RIGEAA---DWFLDK-------------------NTGLYRDAVRYSHFMIEaDLEL-----------YRATNEPY---LL 311  Blastopirellu...
4C1S_A        263 AIAESCh-KKWFMPYrs----keLNLTFNil--aPGHAW-----FNTIMCRgFFEL----------YSIDNDRKYiddIE 320  Bacteroides t...
WP_012186052  279 DSAYAS--LSYFSQG----------AIYS---QPPE--------FNAIYFR-SLEK---VIEISRnNTLSKMYWN---LL 328  Caldivirga ma...
Q9S1S4        294 ADARGS--LAYWTGG---------TRLHD---QPAV--------FNAFYFK-DLLD---LDAVRPdSAYLSAMSA---YA 344  Streptomyces ...
5AGD_A        319 FNIEMAWsHQN------SDHI-VDGNWA-GqlLSgtyesWSSAA-----AVQALNGI 362  Bacillus circulans
ABN64243      341 QGSYVYTtKQDp----dDPNM-Y----------------FNSPT-----TTPQMTKk 371  Scheffersomyces stipitis CBS 6054
O14131        322 KPAQKMV-LDQa---------dFLMKYL-R--IP-----KEGLYyrnfgLYKLSPEL 360  Schizosaccharomyces pombe 972h-
Q6CGF0        312 QLAVEQT----------KRNLvYIYQYL-R--DP-----KDGLY------FQTFEIF 344  Yarrowia lipolytica
WP_005361619  480 DNARVAWmNSNsk-------giMQCSWQkK--AS-----EDATW-------DSFAAY 515  Eubacterium ventriosum
WP_005824849  325 NNAEILWrKGIn----kLDLL-YNTNWAmN--NSgn-----------nhLTTQTSGC 363  Bacteroides
EAQ78697      312 ERAQRNV-DAIytnwkaNTPDdM--------------------------MSSACIAR 341  Blastopirellula marina DSM 3645
4C1S_A        321 KSMIHAWsSSCh-----QGNNlLNDDDL-R--GGttktgWEILHqg--aLVELYARL 367  Bacteroides thetaiotaomicron VPI-5482
WP_012186052  329 LTYVNDTwITYr----dPETGlIT-------------------------MGQPLNSV 356  Caldivirga maquilingensis
Q9S1S4        345 DNTYRSN-RDAss-------glFRFQPS-----------NGGDYd----PAAPAATL 378  Streptomyces coelicolor
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