1H54


Conserved Protein Domain Family
Glyco_hydro_65N
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pfam03636: Glyco_hydro_65N 
Glycosyl hydrolase family 65, N-terminal domain
This family of glycosyl hydrolases contains vacuolar acid trehalase and maltose phosphorylase.Maltose phosphorylase (MP) is a dimeric enzyme that catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. This domain is believed to be essential for catalytic activity although its precise function remains unknown.
Links
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Statistics
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PSSM-Id: 397616
Aligned: 326 rows
Threshold Bit Score: 82.6251
Threshold Setting Gi: 387513564
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1H54_A         13 ITHTFDpkdKRLQESMTSLGNGYMGMRGDFEEgysg------------------dslqGIYLGGVWypdKTRv------- 67  
XP_001273664   71 ATTTLD---QGHYQSRGSVANGYLGINVASVGpffeldtpvsgdv-ingwplfsrrqsFATIAGFF---DFQpttngsnf 143  Aspergillus c...
Q2U6X8         70 KTTTLD---QGHYQSRGSVANGYLGINVASVGpffeldeevdgdv-ingwplysrrqsFATIAGFF---DSQpttngtnf 142  Aspergillus o...
EHA26179       70 TTTTPD---QGHYQSRGSVANGYLGINVANIGpffeldepvngdv-ingwplysrrqsFATISGFW---DRQahtngsnf 142  Aspergillus n...
P78617         67 TTSSLD---QGHYQSRGSVANGYIGISVSSVGpffeldlpvagdv-ingwplysrrqsFATISGFF---DIQaetngsnf 139  Aspergillus n...
CAP93857       63 SSTNLE---QGRYQSRGSVANGYLGINVASAGpffeidspedt----ngwplysrrqaFATISGFF---DSQpttngsnf 132  Penicillium r...
CCT73100       67 STTNLD---QGHYQSRGSVANGYLGINVAAAGpffeidldeeggv-ingwplfsrrqtFATIAGFY---DAQpntngtnf 139  Fusarium fuji...
XP_007825738   67 STTTLE---QGRYQSRGSVANGYFGISVASVGpffeldaedeggdvingwplfsrrqsFATIAGFW---NAQpetngtnf 140  Metarhizium r...
EHK41530       68 sTTQLK---QGAFESRGSVANGYLGINVASVGpffeldteengdv-isgwplfsrrqsFATIAGFW---DSQpvmngtnf 140  Trichoderma a...
EPS26466       70 TTTTLE---QGRFQSRGSVANGYFGINVASVGpffemdnatmggdeingwplfsrrqsFATISGFW---DSQpttngsnf 143  Penicillium o...

1H54_A         68 ------------GwwkngypkyfgkvvNAVNFIKLPIEINge-pVDLAk--dKISDFTLDLDMHQGVLNRSFVVERGA-- 130 
XP_001273664  144 pwlnqyggesviS--------------GVPHWSGLVLDLGddtyLDAAvdneTISGFQSAYDFKSGVLSWSYTWTPTDd- 208  Aspergillus c...
Q2U6X8        143 pwlsqygwdtaiS--------------GVPHWSGLILDLGddvyLDSTvddsTITDFQSTYDFKAGVLSWSYTWSPAd-- 206  Aspergillus o...
EHA26179      143 pwlsqygddsviS--------------GVPHWSGLILDLGddtyLDANvdnrTISNFKSTYDFKSGVLSWSYTWTPQGn- 207  Aspergillus n...
P78617        140 pwmnqyggesviS--------------GVPHWSGLILDLGdddyLDSTvdnvTLSDFKSSYDFKAGVLSWSYTWTPAGd- 204  Aspergillus n...
CAP93857      133 pwlsqygydsviS--------------GIPHWAGIILDLGdgtyLDAKvdnkTISDFQTTYDFKAGVLVWSYKWTPQGn- 197  Penicillium r...
CCT73100      140 pwllqygyesviS--------------GVPHWSGLILDLGddvyLDATvdnrTVHNFTSTYDFQAGVLEWSYTWKPKAq- 204  Fusarium fuji...
XP_007825738  141 gwllqygyesviS--------------GVPHWSGLVLDLGngvyLDSTvdnkTITNFRSTYDFKAGVLSWSYTWSPSAgn 206  Metarhizium r...
EHK41530      141 pwisqygsdtaiS--------------GIPHWSGLILDLGdntyLDATvdnrTLTNFRSTYDYKAGVLSWSYKWTPKGn- 205  Trichoderma a...
EPS26466      144 pwlyqyggdsviS--------------GIPHWSGIILELDdetyLDAGvdnsTISNFTSTYDFQAGVLSWAYQWTPNDk- 208  Penicillium o...

1H54_A        131 -VRVALNFQRFLSVAQPELSVQKVTVKNLsdaEV-DVTLKPSIDADVMNeeanyderfwdvlatdqqadrgsIVAKTTPN 208 
XP_001273664  209 kGSFNITYRLFANKLHINQAVVDMEITPS---QEsQATVVNVIDGYSAVrtdfves----------geddgaIFSAVRPW 275  Aspergillus c...
Q2U6X8        207 kGSFEITYRLFANKLNITQAVVDMEIIPS---VDaNATVANVIDGYSAVrtdfves----------gqddgaLFSAVRPW 273  Aspergillus o...
EHA26179      208 kGSYAITYRLFAHKLYVNRAVVDMEITPL---TNgNATVVNVLDGYAAVrtdfvas----------gqeegaIFSAVRPW 274  Aspergillus n...
P78617        205 kGSYAITYRLFANKLNVNQAVVDMEITPS---QDgHATIVNVLDGYSAVrtdfves----------qeddgaIYSAVRPW 271  Aspergillus n...
CAP93857      198 kGSYQITYRLLAHKLYVNQAVVEMEVIPT---TAsDATIVNVIDGASAVrtdfvet----------gedngaIFSAVRPN 264  Penicillium r...
CCT73100      205 kGSYEIKYRLFAHKLHVNRAIVDLTVVPS---IDsEATIVNVIDGYSAVrsdfvks---------gedddgaIFSAVRPV 272  Fusarium fuji...
XP_007825738  207 nGSYDIRYLMFTNKLHINQAVVDLEIIPS---VDaNATVVNVLDGYSAVrtdfvqs----------gedagaIYSAVRPT 273  Metarhizium r...
EHK41530      206 kGSFDISYRIFANKLYVNQAVVDMEVTSS---KNvQASIVNVLDGFAAVrtdfves----------gqdgnaIFSAVRPN 272  Trichoderma a...
EPS26466      209 yGSFDISYRLFVNKLYVNQAVVDMTIVAS---QDsNGTIANVLDGYSAVrtdfves----------geddgaIYSAVRPN 275  Penicillium o...

1H54_A        209 P-----------FgtpRftsGMEMRLVTDLkn-vaItqpN--E----KEVTTAYTgkLAPQASAELEKRVIVVTS 265 
XP_001273664  276 GianvtayvyanL---T---ASKN-VDLAShtlvaD---KpyIhtneSSVAQAVRvnFRANETVRITKFVGAASS 340  Aspergillus clavat...
Q2U6X8        274 GisnvtayiytnL---T---GSAN-VDLSSrtlvtG---KpyVntneSSVAQTVNvkFTAKEPVRITKFVGGAST 338  Aspergillus oryzae
EHA26179      275 GvnnvtayvyatL---D---GSDS-VDLSSrrivtD---KpyVstnsSSVAQAVDvtFTANETVRITKFVGGATT 339  Aspergillus niger ...
P78617        272 GipdvsayfyanI---T---GSKH-VDLSSrrlihG---KpyVsaneSSIAQAADvnFVANEKVRITKFVGAAST 336  Aspergillus nidula...
CAP93857      265 GianvtayvyanL---T---GSPN-VDLSSrkivsD---KpyVhsneSSIAQAVDvkFKPGQLVRVIKYVGGAST 329  Penicillium rubens...
CCT73100      273 GianvtafiyaqV---N---GSKS-LDLSRrklvhG---KpyVhtneSSIAQAIPvkFSAGVPVHITKYVGAASS 337  Fusarium fujikuroi...
XP_007825738  274 GianvtayiyanM---T---GSDD-VDIGRktlvsN---KpyIrkneSSIAQAVPvtFSAGKAVRITKYVGAASG 338  Metarhizium robert...
EHK41530      273 GvsnvtafvyadI---T---GSGG-VNLDSrkivkS---KpyVhtnaSSIAQAVSvkFSAGHAARVTKFVGAASS 337  Trichoderma atrovi...
EPS26466      276 GianvtayvyanM---T---GSSSAVDLSSrklveS---KpyVssnsSSVVQTASisFKKGKKVQVTKFVGAAST 341  Penicillium oxalic...
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