3ABI,1E5Q,2AXQ,4INA,4XQE


Conserved Protein Domain Family
Sacchrp_dh_NADP
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pfam03435: Sacchrp_dh_NADP 
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Saccharopine dehydrogenase NADP binding domain
This family contains the NADP binding domain of saccharopine dehydrogenase. In some organisms this enzyme is found as a bifunctional polypeptide with lysine ketoglutarate reductase. The saccharopine dehydrogenase can also function as a saccharopine reductase.
Links
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Statistics
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PSSM-Id: 397480
Aligned: 81 rows
Threshold Bit Score: 57.9854
Threshold Setting Gi: 81836163
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3ABI_A         19 VLILGAGNIGRAIAWDLKDEFD-----VYIGDVNNENleKVKEFA-----TPLKVDASNFDK-LVEV-MKEFELVIGALP 86  Pyrococcus hor...
A0BRK4         35 IGVLGYGAIGKAFTELLLKQHPka--nIVILDKHDAFfpNEkrf----ktVIYKQTRDNLTQtLDIMgLKEGDTLVDLST 108 Paramecium tet...
A0DNM8         20 IGVLGYGAIGSAFIEVLLKNHPna--qIVALDKYNAFraNEnrf----ecIIEERTKENIGDtLSRMgLQSGDILVDLST 93  Paramecium tet...
WP_012507661    8 ILIIGFGSVSQCTVPVLFKHINvdytqVTIMDFEDIRekVSPWTAlgvtyINHQITPYNIAQtLSSY-VAEGDLIIDLAW 86  Pelodictyon ph...
Q8TQB2         16 ILVIGYGSVSQCTLPLLLDKLDvplenITLIDFEDKSkaLKKYTNqglrfVCEKINPKNLDQvLSQY-MEDEGLIIDLSW 94  Methanosarcina...
WP_012106592    7 VLIIGYGAVSKCTLPILLRHVNiplenITIVDFKDKSqdLKAYTTrglrfLKRKITPENLTSiLTET-LGEGGLLVDLAW 85  Methanoregula ...
ABU43831       34 ILQIGCGGVGSSMPPLYKKHLKfssgnVIIIDKDRIKidKLSEKYpsmkfINTEVTKSNYKNiIDQH-LKKGDVFVDLAW 112 Paramecium bur...
ABT16724       41 ILQIGCGGVGSSMPYLYERHFQykagnITVMDKDKARldKLKAKFpkinfVHQEFTKKNYKQiITQY-LGKGDIFADLAY 119 Acanthocystis ...
jgi:Sama_3337  14 ILIVGFGSIGQGLLPLILRHIDitpqkICIITADDRG--REEAGKlgirfIEMPLTRKNYQSeLTPL-VGKDDFLVNLSV 90  Shewanella ama...
Q5WTV7         16 FVILGFGCIGQALMPLIFDKFDikpsqVTIIAAEGTK--IDAAQQygvsfKLQQITPQNYLEvIGST-LEENDFLIDVSI 92  Legionella pne...

3ABI_A         87 GFLGFKSIKAAIKSKVDMVDVSF---------------------MPENPLELRDEAEk-----AQVTIV 129 Pyrococcus horikoshii
A0BRK4        109 NIGFAEIWALCASKGVRYLNTALevwddsedanscpqnaeeaykLTLGYIKDNAKKSpf--wqKGPTSL 175 Paramecium tetraurelia
A0DNM8         94 NIEFLSIWSLCAEKKIRYMNTALeqwedsedanscpknseeaykLTLGYIKDKAKQSkywnpkSGATSI 162 Paramecium tetraurelia
WP_012507661   87 NIDCCEILQWCHDHGVLYINTSVevwdpytgvetrppaertlywRHMNIRRMTSQWKd-----KGVTAV 150 Pelodictyon phaeoclathrat...
Q8TQB2         95 NIDANDILTWCHNHSVLYVNTSVevwdptedfltrsllekslylRQMKLRELSRDWK------DSPTAV 157 Methanosarcina acetivorans
WP_012106592   86 NIDAGEIVQWCHDHNVLYVNTSVeawdplgerytaspvekslyyRQMKLRELTREWA------DSTTCV 148 Methanoregula boonei
ABU43831      113 YMNTKDLLTYCHEKGIHFVNTAIeswygeedckaktkecetlyrHQHAVRELAKSWGn-----KGATAV 176 Paramecium bursaria Chlor...
ABT16724      120 YIGTNDCLELCHEKGIHFTNAAIeqwlgssdcnqntlecetlyrHQHYVREMAKKWGn-----KGATAV 183 Acanthocystis turfacea ch...
jgi:Sama_3337  91 DVSSIALVEFCQARGARYLDTCIepwaggytdpsksfaarsnyaLRERVLALKDKYR------GGPTAV 153 Shewanella amazonensis SB2B
Q5WTV7         93 GISSLALIILCNQKGALYINAATepwkeefvmekmalnrrtnysLREEVLRLKDKTQ--------KTAL 153 Legionella pneumophila st...
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