Conserved Protein Domain Family
Herpes_IE2_3

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pfam03361: Herpes_IE2_3 
Herpes virus intermediate/early protein 2/3
These viral sequences are similar to UL117 protein of human and chimpanzee cytomegalovirus, and to intermediate/early proteins 2 and 3 of certain herpes viruses. UL117 is thought to be a glycoprotein that is expressed at early and late times after infection. This region is close to the C-terminus of the protein and may be a transmembrane region.
Statistics
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PSSM-Id: 281370
Aligned: 5 rows
Threshold Bit Score: 195.013
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P52532  167 PYSPCSPKNFMSE-IyRLFRCYNASIVQIQV-YSRNKIL---INAMQEKLMSIGNMVINVGEQI-ISESVHHEPVVAIAI 240  Human herpesvirus 6...
Q6SW29  383 PFMIPSMHQVLEEaI-KVCKTMQVNNKGIQIiYTRNHEVkneVDQVRCRLGSMCNLALSTPFLMeHTMPVTHPPDVAQRT 461  Human herpesvirus 5...
P29832  424 PFRPQSPQYLLGKaI-QFCKEETVHDKFIMLfYTRSQDVrkaVDETRARMGMRPNLSISCPFMTeHTKPINHSRETIDRT 502  Murine cytomegalovi...
Q9QJ16 1348 PKKP-FPENKLKEaVyNICSNGCSNTGAIIMyFTRSKQVaeiIKTMQRELMIRPNITVSEPFKMnHAPPNYYDKDAINQF 1426 Human herpesvirus 6...
F5HFA5  261 PLFASKYKYVFEE-VsRLMRLHDSTAVQLQI----SASCgnaFQALKSALLKLHNVTVLAGQQL-ITQTMPHTPQAVATF 334  Human herpesvirus 5...
P52532  241 NQFFRGTVPQTDALRKNAVTPIPVNASKKKlvgicSLMINAPTEKDLLCAAHVCINFAICYPNEITLNIAKLTQPMLLqe 320  Human herpesvirus 6...
Q6SW29  462 ADACNDGVKAVWNLKELHTHQLCPRSSDYR-----NMIIHAATPVDLLGALNLCLPLMQKFPKQVMVRIFSTNQGGFM-- 534  Human herpesvirus 5...
P29832  503 SAACTAGTQAVWDMEERRGQKCVPRTSDYR-----SMIIQAANPPDFLGAVKTCLHLSQVFPKQVCMRLCSITGGLNP-- 575  Murine cytomegalovi...
Q9QJ16 1427 IELQKQGPQELWDKLENNTHDLFTRHSDVK-----TLMVYAATPIDFVMASKICNKYAKDKPKEIVLRVCSIIDGDNS-- 1499 Human herpesvirus 6...
F5HFA5  335 KFFHQDPNRVLDCIR-----PVVPRSTSYHetgvyQMWVSGATKKDLFDAVTLCASIVEKQPDVFNINVSLLTYPSIAap 409  Human herpesvirus 5...
P52532  321 hITIYNSFNK 330  Human herpesvirus 6 (strain Uganda-1102)
Q6SW29  535 -LPIYETAAK 543  Human herpesvirus 5 strain Merlin
P29832  576 -LPIYEETVS 584  Murine cytomegalovirus (strain Smith)
Q9QJ16 1500 -ISIYNSVSR 1508 Human herpesvirus 6 strain Z29
F5HFA5  410 hLPLYNEFTS 419  Human herpesvirus 5 strain Merlin
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