2IQQ


Conserved Protein Domain Family
SDH_beta

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pfam03315: SDH_beta 
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Serine dehydratase beta chain
L-serine dehydratase (EC:4.2.1.13) is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyzes the deamination of serine to form pyruvate. This enzyme is part of the gluconeogenesis pathway.
Statistics
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PSSM-Id: 397413
Aligned: 325 rows
Threshold Bit Score: 90.5328
Threshold Setting Gi: 565681685
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2IQQ_A                     13 IGPSSSHTVGPXLAANAFLQLLE------------QKNLFDK-----TQ---RVKVELYGSLALTGKGHGTDKAILNGLE 72  Le...
BOB002_L21SP2:L21SP2_2363  14 PGPSSGYTLAALRAAAAFRGLIReyflqhqssvaeLKHNISEeafhhPAgkyYIRVLLLGTMSARQHDYLMYEALCSGLS 93  Sa...
Q7NI26                     16 PGPSSSHTIGPMKAAFDFLIRINa---------------LDDtqvlaAS---AVEAFLFGSLSATGKGHGTDRAVIAGLL 77  Gl...
ASGPB:GKIL_2588            16 PGPSSSHTIGPMKAAFDFLSRTSa---------------LDRsvldqAA---AIDIFLYGSLSATGKGHGTDRALVAGLL 77  Gl...
jgi:Runsl_0589             19 PGPSSSHTIGPMKAAYLFLQQLTh---------------LPPeqarrGK---TFQINLYGSLSATGKGHGTDRAIVGGLL 80  Ru...
WP_015332684               14 PGPSSSHTIGPMKAAYDFVQRMAs---------------LLPdqleaAD---ALHIHLYGSLSATGKGHGTDRAIVAGLL 75  Fi...
jgi:Lbys_1842              27 PGPSSSHTIGPMKAGYDFLQRI-------------------QsifleEGtelRIEIHLYGSLSATGKGHGTDRAVIAGIL 87  Le...
jgi:Emtol_2631             18 PGPSSSHTIGPMKAAYDFLQRAKa---------------SAQsttlhQP---KIMIHLYGSLSATGKGHGTDRAVIAGLL 79  Em...
Q01WN4                    103 PGPSSSHTIGPMRITYDFYQRCTk---------------LPAadlaqAT---ALKVNLFGSLSATGKGHGTERASLAGLV 164 Ca...
jgi:Desal_0783             16 PGPSSSHTIGPMKAGYNFHLAVAd---------------LSFeeq-----pdNIEIRLYGSLSATGEGHGTDRAVVAGLL 75  De...
2IQQ_A                     73 NKA-----------------------PE-TVDP------------ASXIPRXHEILDSNLLNLAG-KkE-----IPFHEA 110 Le...
BOB002_L21SP2:L21SP2_2363  94 GREipgvhssaevhprnevdplnvvdPLnEVDPlsevspeettwrDMMISDARQLEKIGKIPDPGgDtD-----VEFHPS 168 Sa...
Q7NI26                     78 GWT-----------------------PE-GCDP------------VAFSALLSDDNEHYFVAIHd--rR-----IPISAA 114 Gl...
ASGPB:GKIL_2588            78 GWT-----------------------PE-GCDP------------AAFSQLLTRPDDCYTVRIHd--rT-----FVISAQ 114 Gl...
jgi:Runsl_0589             81 GWQ-----------------------PH-TCDP------------KQLSGLMKNKEDSYTIRFQe--iE-----VPITEN 117 Ru...
WP_015332684               76 GWQ-----------------------PD-TTDP------------DALLNLLRDPADTYPVVIGp--kT-----FPVNAA 112 Fi...
jgi:Lbys_1842              88 GWQ-----------------------PD-TVDP------------QAFTSLLQHPDSSYTVYIGn--rT-----VQVDAS 124 Le...
jgi:Emtol_2631             80 GWL-----------------------PD-TCEP------------TAFTALLKNPDDLYITQVGn--yE-----VSLTAR 116 Em...
Q01WN4                    165 GKE-----------------------PA-TVDP------------AFLDSLRDQPDQSFPVKLGp--kT-----VDVTLK 201 Ca...
jgi:Desal_0783             76 GFK-----------------------PE-NVEC------------EFLDSLADGTSR-----------QfesgrISLGLS 108 De...
2IQQ_A                    111 -TDFLFLQKELLPKHSNGXRFSAF-----DGnanllIEQVYYSIGGGFITTEED 158 Legionella pneumophila subsp...
BOB002_L21SP2:L21SP2_2363 169 -RSIISGGSISVPGFSRGVEFQLFsrseeSGeh-liLSRRWYSIGGGVICDDaf 220 Salinispira pacifica
Q7NI26                    115 --NIHFVKGQQDFPFSNTMILRLM-----GDds-vlFEQEYYSIGGGFIQRKGE 160 Gloeobacter violaceus
ASGPB:GKIL_2588           115 --HIHFVRGQHDFPFSNTLIVRLT-----GVeg-tlYEEEYYSVGGGFIQRKGE 160 Gloeobacter kilaueensis JS1
jgi:Runsl_0589            118 --AIVYHKGRTTFPHPNTMILRLL-----DEggesvYEGEFYSVGGGFIQQKGy 164 Runella slithyformis DSM 19594
WP_015332684              113 --SLHFERVRYDSPYANTMVLRLS-----SGth-piAEEEYYSIGGGFILRKgd 158 Fibrella aestuarina
jgi:Lbys_1842             125 --SILFQKGRYDSPHPNTVIFKLL-----ADgf-rvHEEEYYSVGGGFVVRKGD 170 Leadbetterella byssophila DS...
jgi:Emtol_2631            117 --NIVFERKRYESPHPNTLVFKLI-----ENeq-ivLGEEYYSVGGGFIQRKGE 162 Emticicia oligotrophica DSM ...
Q01WN4                    202 --DVVFDATDGNFPHPNTMTVKLM------AgnkvlLEQEYYSVGGGFIEWKGy 247 Candidatus Solibacter usitat...
jgi:Desal_0783            109 vKDVVFAEVENDFPYANTLLLRLR-----KGee-ilFEQEYYSIGGGFIKWKGQ 156 Desulfovibrio salexigens DSM...
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