5I3E


Conserved Protein Domain Family
DNase_II

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pfam03265: DNase_II 
Deoxyribonuclease II
Statistics
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PSSM-Id: 397390
Aligned: 84 rows
Threshold Bit Score: 117.38
Threshold Setting Gi: 470253696
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5I3E_A         14 RDEQN---------------RSVDLWFAYKVPkltkdadsdsaSGYEYVYYDRQVGa-VQKSPNLMNDPKGA-L-----F 71  
Q55D42         26 ITTKNvytksqv-fidkdgeKNVEWWVLEQLS-----------QSQGAIYTDNE----LNGANPVINELAYYnIrnpdeP 89   Dictyostelium...
Q55D38         26 ITTKNiykdgqvfgdgvtieKNVEWWFLEQLG-----------HSKGSIYTDNT----LKGGSSEINEIANYnIrdpkeP 90   Dictyostelium...
EFA81407       24 VNPEG---------------KAVKWWIHLADAdsat----eenMYARGLYYDSL----LDLMKKHVDQANGDkI------ 74   Heterostelium...
EFA79444      988 LSPSG---------------AAVSWWFARKLP-----------QSSSYLYFDSQSS--VVQYFDSINSNSSS-L-----A 1033 Heterostelium...
EFA77037     2660 LSTQG---------------ASVSWWFVRKIP-----------QSQSYIYVDSDSQ--DMKYLPSINSTTGC-L-----A 2705 Heterostelium...
EGR29926       25 RNQND---------------ELVDWFIILKHP-----------QGTEYSYCDSNECtqLRSTGLDLNNPKDSpL-----L 73   Ichthyophthir...
Q22N03         25 LDPRG---------------KSVDWFIVLKHP-----------VGSEYSYCDSNSCtqLKSQGFELNDIDNSpL-----M 73   Tetrahymena t...
XP_004359946   46 KSPTG---------------DSVQWWFIKKLP-----------YSNQYIYIDNDSK--TIQFQNDLSDDQSS-L-----A 91   Cavenderia fa...
XP_001010838   23 INPNG---------------AQVDWFITLKLN-----------NGDDYAYCDSKSCdkIQLSGFKINDAKNSpI-----L 71   Tetrahymena t...
5I3E_A         72 YTLDSV--------F--------GDP-GD-TTG------WILYNDEmpa--------------daNRSNNATLGHTKGVI 113 
Q55D42         90 NPITST--------Y--------IQ--SYpNKSgktiynSLTYNDQp--------------------sNSGNSAHAKGFF 131  Dictyostelium...
Q55D38         91 NPITST--------Y--------KQ--SLpNESkkiiynSLTYNDQi--------------------sGGSDSAHAKGFF 132  Dictyostelium...
EFA81407       75 -TEQQC--------I------------DKnYLG------LEWYHDQgye-------------hrvIDNSVFYHGHVKSLY 114  Heterostelium...
EFA79444     1034 LTLNQI--------K--------SNN-VQtTNG------YLAYNDMpwlddls-----gklaqslTGDVNKYNSLGKGIL 1085 Heterostelium...
EFA77037     2706 RTLNQI--------A--------ISS-SEsSNG------YVVYNDHpwfddls-----gqlslsiNGYGNLNKSLGKGIF 2757 Heterostelium...
EGR29926       74 NTLKQI-----------------QKV-DSsEYG------SIFWNDQp-----------------pQQKASFNVAHSKGVM 112  Ichthyophthir...
Q22N03         74 RTLAQT-----------------ERIgKQsPYG------SVFWNDQp-----------------pQSDASLSYAHAKGFM 113  Tetrahymena t...
XP_004359946   92 RTLSQLsqqqqqqqLnggggggsDQN-DNsDYY------YYFYNNEfqnlnsndrtnfplpadksTIQPSTVYSSSKGIV 164  Cavenderia fa...
XP_001010838   72 RTLQQI-----------------KQNlNNdKQG------YLLWNDQpp----------------nNMTATSSNAHAKGFI 112  Tetrahymena t...
5I3E_A        114 AF-----DiaSS------SALWLLHSWPK-----------YASPSVP----GV-----------PTP----LYGQTFL-- 150 
Q55D42        132 IW-----N--EE------GGIHVIHSVPNs------------pETGYkplfNF-----------KENtlksQHAQHSI-- 173  Dictyostelium...
Q55D38        133 IW-----N--EE------GGIHVIHSVPKs------------pETGYeplfNY-----------DKDtlnnQHAQHSI-- 174  Dictyostelium...
EFA81407      115 VFdlrdnD--IDs----nTGFFVSHSMRmpelks-tgsglYEKAKWY----STittcilihtqlPKKycmeNEGPFTLgs 183  Heterostelium...
EFA79444     1086 VS-----Q--SKfnisyaPGFHIKHSLEGfpvpl-gstgaIKTPSSYpd-gTWfpnd---yhlrPTEspdlSFGHSFL-- 1151 Heterostelium...
EFA77037     2758 VA-----N--TFfnatysPGFHIKHSMEGfpvpl--pnglFKTPSSHp--sSWipnd---yhliQNQgddySLGHSFM-- 2821 Heterostelium...
EGR29926      113 GF-----G--QN------QGFILIHSAPKfpeiink----------------------eivlqiESGq--lVFGQHFF-- 153  Ichthyophthir...
Q22N03        114 VF-----N--QE------KGYLMVHSTPRfpvieed----------------------ivnleiPSSq--tKFGQHYF-- 154  Tetrahymena t...
XP_004359946  165 ILnkpplQ--NNntnktfSGAYIVHSLSRfpqltttttnsFKTPITHpn-gTWfptdyylsplsPSPs--sSYGHSLV-- 237  Cavenderia fa...
XP_001010838  113 SL-----G--QK------SGFILIHSVPEfpafadsss------------------lkeillniEESq--qKYGQHFL-- 157  Tetrahymena t...
5I3E_A        151 ----------------------CLSLDl-aTAGKLAAQMaLHQQPQVY-----LPrt---ggLDhTSPLYALTQPLNASA 199 
Q55D42        174 ----------------------CITLSk-eELHIIPKYI-IYGNLNIQti-ntVSpgs--gaKR-VSSAMFLYSQVLKEE 225  Dictyostelium...
Q55D38        175 ----------------------CITLSk-eELHIIPKYI-IYSNLNIQti-ntVStglgkkaKK-VSSAN-LYSENLHTE 227  Dictyostelium...
EFA81407      184 fttfsfsadkendkknyktlskCFALNygkKIQNI-----KFENDFTFe------------nKD-NPIKVDMLSTTHCLS 245  Heterostelium...
EFA79444     1152 ----------------------CHSFVdatEIINAIVAM----KPFTYasnrfTAn------SN-M--FTPMFQSTAAVI 1196 Heterostelium...
EFA77037     2822 ----------------------CHSLIdssDFVNGIQSL----KPFIYssnrfTPt------ST-TNIFSSLFTDSTTN- 2867 Heterostelium...
EGR29926      154 ----------------------CISSSt-sELDAIAQAY-NVDWPMVYdg--nVAf------EG-LQYLKDMLNNERNEK 200  Ichthyophthir...
Q22N03        155 ----------------------CISTTt-eDLNKIAEGY-NIDYPKVYss--yIPte----fEG-IDNIINMVNQKRNKD 203  Tetrahymena t...
XP_004359946  238 ----------------------CTSFK---DYEDVRYQI-QSIYPYIYmtnlnLP-------FK-DPLLKSTFNSLFYPT 283  Cavenderia fa...
XP_001010838  158 ----------------------CTSTSl-eNLEKLACGY-NIDNPKVYss--fLPyyi--dqSS-YPCLNQMKNNKRNTK 208  Tetrahymena t...
5I3E_A        200 ------------P---GDSDSLDFKTrg----gVPFKVIAKNRK-WGKDFwndlvgptlKADMYVE---TWIR------- 249 
Q55D42        226 vdkkktgvidldVidsKILATKIPKTfkeldglMSEYIFDNKKNdGDPDIwng--------viYLN---KWSQl------ 288  Dictyostelium...
Q55D38        228 vekisp-gvinlDv-iENLAKEIPKTfkkldglMSDYILVKKKNdGDPDIwng--------iiYLN---KWSQl------ 288  Dictyostelium...
EFA81407      246 ndvpkddsicydAktvCSFTDFGMDPyllvaqhYDSHFFVSTDQ----ETfpsligstfSVRNIVTwspIWSRe------ 315  Heterostelium...
EFA79444     1197 ------------P---PFRSSSWLTNt-----aFLSSAFQQ-------DIftpvglsplLITMPANfklPIAAtai---- 1245 Heterostelium...
EFA77037     2868 ----------------------SFTSkdwskgyFISAGFRN-------DIftptriqplSITLPSKfkiPSGAnai---- 2914 Heterostelium...
EGR29926      201 ------------D----HKLTVEFTSlq----gTKFLKMAKSGH-WEVPFydnvvteqlKTGLYVE---SWGSp------ 250  Ichthyophthir...
Q22N03        204 ------------D----QQLAVNFKSlk----gTKFIKFSKSGK-YLVPFydtilaesiKAGVIVQ---SWGSp------ 253  Tetrahymena t...
XP_004359946  284 ------------Yp--PKSLYLKPDA-------IKLQSLSSRDDnGDRDP---------NSSISITssiKWGGasiwhss 333  Cavenderia fa...
XP_001010838  209 ------------T----KQMIITYSTln----gETFTKFSKNKD-NQIPLyeqivtqelKTGLLVQ---SWGRp------ 258  Tetrahymena t...
5I3E_A        250 -------------GKIPPv--lDSD-------GVHKTYDIK-FIDL----RKLGApwAWPETQDHAKWGITTT-DN--WV 299 
Q55D42        289 -------------ADLIL----NKDitssdtnLKPKETNVH-YYKI--------------NESDKGRYFIQTTnIN---- 332  Dictyostelium...
Q55D38        289 -------------AKLIL----NEDitssdltLKPKETNVH-YNKI-------------YESKNKGDYFIQTTnKN---- 333  Dictyostelium...
EFA81407      316 --------------------------------------------------KKDGE--NSESRSRHEKLMVSKS-KN--II 340  Heterostelium...
EFA79444     1246 -----------teTKLPS------------------------DFVSqhniPMQIS--QWRASRDHSHIGFNDT-----HL 1283 Heterostelium...
EFA77037     2915 -----------tdVKLPT------------------------EFIIqnniPTKIS--QWKSDIDKSYIAFNDT-----HL 2952 Heterostelium...
EGR29926      251 --------------QENS----DCH-------QQYEVLSNI-EVKM-----PTGE--KYKFTKDHSKYAISSN-PTtpFV 296  Ichthyophthir...
Q22N03        254 --------------QEEP----ICE-------SQYNVSSNM-LITL------DGI--TYKQTQDHSKYCISTD-DSkpYV 298  Tetrahymena t...
XP_004359946  334 ntinyisipskykNPLPTnngkNSTmvsspitHVINSQKLPgDLVTryriDSDKS--QWDTSVDKGIFGVSTI-QS--LS 408  Cavenderia fa...
XP_001010838  259 --------------YEEA----SCS-------GSYQVVSNT-RVQI-----DGAP--QFKDTQDHSKYGISID-KAkpFV 304  Tetrahymena t...
5I3E_A        300 CVGDINRmVTQEKRGGGTIAFQDPKLW-------------KA 328 
Q55D42        333 LYKEYSEkNKEAHKDG----IKFFIVWhfidsskndlpngNN 370  Dictyostelium discoideum AX4
Q55D38        334 LYKKYNEkIEETHKEK----IKFFIIWhyidn----fkngNN 367  Dictyostelium discoideum AX4
EFA81407      341 CLGDSNRnDYSVHHAGTIFCIENEILA-------------KR 369  Heterostelium album PN500
EFA79444     1284 CLGDYS--AKTTIGGGMAVCIKQTVLS-------------DF 1310 Heterostelium album PN500
EFA77037     2953 CLGDYS--SKTSFGGGIAVCVINQFSS-------------EF 2979 Heterostelium album PN500
EGR29926      297 CLGDINRqNSQWKRGGGTICFRNGNAY-------------KA 325  Ichthyophthirius multifiliis
Q22N03        299 CLGDINRqTSQWKRGGGTVCLQNKQVH-------------TA 327  Tetrahymena thermophila SB210
XP_004359946  409 CIGDYDQ-NINSANGELMICINNSILS-------------SL 436  Cavenderia fasciculata
XP_001010838  305 CLGDINRmKSQWKRGGGTICISNKNIH-------------FQ 333  Tetrahymena thermophila SB210
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