Conserved Protein Domain Family
Prothymosin

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pfam03247: Prothymosin 
Prothymosin/parathymosin family
Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.
Statistics
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PSSM-Id: 397379
Aligned: 15 rows
Threshold Bit Score: 29.5231
Threshold Setting Gi: 557011910
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q28G57         2 ADTDVDTTTaeVPVTKDLKEK-KEV-VEEPEKAEng--kgDAPSNGT---EENGADHGAQNDdaeeEDEEGDvegEGEGE 74  tropical clawed...
XP_005997417   2 SETKVDHPS--ETPAKDLKEK-KE--VEGSGNGK------EVPANGNaenEENGEQEVENEVd---EEEEEEageEDEED 67  coelacanth
Q5BL59         2 SDTAVDASV--EKTPKDLKAKeKEV-VEEAENGK------DKPTNGNaenEENGEQEn--------EGDEEEevdEEDEE 64  tropical clawed...
A5PLC8         2 ADAKVDSAT--EISAKDLKE--KKL-IEEKENGK------DA-TNGKe-nEENGEPEID--------DEDDDevdEDDE- 59  zebrafish
XP_006642006   2 ADTAVDTTTttEVTPKDLKEK-KEV-AEEVEKTEkengsgDAPANGT---EANGADHGEETPedeeEEDE-----EAEGE 71  spotted gar
XP_003459621   2 ADTAVDTTAtaEVTAKELKEK-KEAeVEEKtd------ngDAPANGT-----NGAEHSDKVEetteEEHKNG-------- 61  Nile tilapia
XP_005155974   2 ADTAVDTTTtsEITAKDLKEK-KEV-VEEAAEAAkengseDAPANGNg--TTNGASHEEEEAhedeEGGE-----DEEA- 71  zebrafish
P08814         2 SEKSVEAAA--ELSAKDLKEK-KEK-VEEKAGRK-------ERKKEVveeEENGAEEEEEET-------------AEDGE 57  cattle
XP_006006539   2 SDAAADTTE--EVSTKDLKEK-----ISGKEKSEp----gAETTDVNgeeEENGAEADEETPeklnDED------EGDEE 64  coelacanth
XP_015216401   2 ADTKVDTSS--EIPTKDLKEK-KEL-VEDAENGK------DTPANGNaenEENGEQEAENEVe---DDDEDEvgeEDDEE 68  spotted gar
Q28G57        75 GEEEEDEEEGEgDENETDGLSVKRPAED----EEK----TETKKQKTENG 116 tropical clawed frog
XP_005997417  68 DEGEGEEED---DDEEAEGATGKRAAED----EEDd--eVETKKQKKDED 108 coelacanth
Q5BL59        65 DEVEGDDDD---EDDEVEGATGKRAAED----DEDddddVETKKQKTDED 107 tropical clawed frog
A5PLC8        60 -EGEGDEDEDEdDDDEDLGGGTKRGADDdedeDEDdeddVDPKKQKVn-- 106 zebrafish
XP_006642006  72 GEEDEEGEEGAeEE--ADGHPVKRPAEE----EEK----VETKKQKTENG 111 spotted gar
XP_003459621  62 ----EGNAEEApPAEETDAQPVKRAAEE----EEEk---VETKKQKTEEN 100 Nile tilapia
XP_005155974  72 -GEAEEEENGAeEEAAAEEHPVKRPAEE----EEA----VETKKQKTEEN 112 zebrafish
P08814        58 EEDDGDEEDEEeEEEEDEGPALVRAAEE----EDE----ADPKRQKTENG 99  cattle
XP_006006539  65 DEEEVDDEEEEdEEDEEEGQAVKRRADD----DDN----TGKKKQKT--- 103 coelacanth
XP_015216401  69 DDGEGEDDE---DDEEAEGGAGKRAAED----DDEd--dVETKKQKTDed 109 spotted gar
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