Conserved Protein Domain Family
PRA1

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pfam03208: PRA1 
PRA1 family protein
This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18.
Statistics
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PSSM-Id: 397359
Aligned: 168 rows
Threshold Bit Score: 52.1382
Threshold Setting Gi: 514817822
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002500004  20 WNMRPRPLTEFF--ARFTPPKSQGKLTSRLKCNIYYYRANYFALLVLSFVVAFFRNPFALFACAMSCLSLLCAND----- 92  Micromonas commoda
Q4DGY3        56 QLAMVRPWKEFFdrECFLPPSGLSESLSRLNRNINHYYHNYMIMAMLCSSYVLLLNPAFSLCVALTLAMWWFVGTkrvea 135 Trypanosoma cruzi
Q389C4        62 QLNRVRPWSQFFdrEQFASPEGFGDAVSRLRCNVVHFYHNYFVVALLGSLIVLIVNPMFSICMFLMLLMWAYTHKkqmea 141 Trypanosoma brucei
EMG45492      32 TISKLRPPQEFFdfRRISKPANFGEIQQRVGFNLGYFSANYIAIVLALSVYALVTNFLLLFVTVFVLGGIFGINk----- 106 Candida maltosa...
CAZ85909      31 RFSNLRPLGEFFdfKRLSKPNNFGEAQSRASYNLGYFSSNYAVVFVMLSIYSLLTNLLLLFVIILVAGGMWGIGr----- 105 Perigord truffle
CBF81237      30 RFANLRPISEFLdfKRLSKPANFGEAQSRVNYNLSYFSSNYAAIFVLLSIYSLLTNPLLLFVIFLVSGGLWGIGk----- 104 Aspergillus nid...
EAW11151      30 RFANLKPISEFLdiKRMSKPANFGEVQSRVNYNLSYFSSNYAAVFVMLCLYSLLSNLRLLFVIVLVTGGLYGIGk----- 104 Aspergillus cla...
EHY52304      32 RFANIRPISEFLdlKRLSKPHDFGEVQSRVNYNLSYFSSNYAVVFVMLSIYSLLTNLWLLFDIILVAGGMWTIGk----- 106 Exophiala derma...
EEH10570      32 RFSNLRPLSEFFdiKRVSKPANFSEVQSRVNYNLSYFSSNYTVVFVMLSIYSLLTNLILLFVILLAIGGSYGIGk----- 106 Histoplasma cap...
XP_011116158  30 RYSSLRPVSEFFdfRRMSRPANMGEAQTRIGFNLGHFSSNYLLVFMLLAIYAVITNLPLLFLIIMIIGGVYGIGk----- 104 Dactylellina ha...
XP_002500004  93 --SFaqsmSEKITrtvRkYHPPTaAwmRRnanvaaapsrpyskskvvhicgfqrlHVVAFLCVLSFFMLRSSRAVSTVLW 170 Micromonas commoda
Q4DGY3       136 leTN----SNHFI---V-LNRKI-T--FS--------------------------QAYLFIAIFAGISFFITNGSSVVFW 178 Trypanosoma cruzi
Q389C4       142 aeTN----VNHLL---I-GNYEI-S--FS--------------------------KAYILISIFGIISFFLFNGSSVMFW 184 Trypanosoma brucei
EMG45492     107 --LN----GEDLV---L-PVGRF-T--TS--------------------------QLYTGLLIVAVPLGFLASPISTMMW 147 Candida maltosa...
CAZ85909     106 --LG----GRDLD---I-GPVHA-T--TS--------------------------QLYTTLLVVSVPLGIFASPISTILW 146 Perigord truffle
CBF81237     105 --LG----GRDLD---L-GFARF-N--TS--------------------------QLYTGLLIVAVPLGFWASPIATFLW 145 Aspergillus nid...
EAW11151     105 --LQ----GRDLD---L-GFARF-T--TS--------------------------QLYTGLLVVAIPTGLMASPFTTILW 145 Aspergillus cla...
EHY52304     107 --LG----GGDLE---I-GTFRA-T--TS--------------------------QLYTGLACIAIPVAFISSPISTFLW 147 Exophiala derma...
EEH10570     107 --LE----GRDLE---I-GGFRA-T--TS--------------------------QLYTTLLIICVPLGLWASPLTTALW 147 Histoplasma cap...
XP_011116158 105 --LE----GRDLQ---V-GNFRA-T--TS--------------------------QLWGTLGVVGFVLAIMSAPFETVFW 145 Dactylellina ha...
XP_002500004 171 ALGMFAVGTLAHASLRSPNLKARL 194 Micromonas commoda
Q4DGY3       179 LVLSSVGVVVVHAVLRKPQIEeqp 202 Trypanosoma cruzi
Q389C4       185 MFFASLGVATVHAVLRKPHSENEL 208 Trypanosoma brucei
EMG45492     148 LIGSSAVTVGSHAALMEKPIETVF 171 Candida maltosa Xu316
CAZ85909     147 LIGASGTCILAHASFMDKPIENAF 170 Perigord truffle
CBF81237     146 LIGATGVTVFGHAAFMDKPIENAF 169 Aspergillus nidulans FGSC A4
EAW11151     146 LVGATAVTVFGHASFLDKPIENAF 169 Aspergillus clavatus NRRL 1
EHY52304     148 LIGASGVTILGHASLMDRPIENAF 171 Exophiala dermatitidis NIH/UT8656
EEH10570     148 LIGATGVTVLGHASFMDKPIENAF 171 Histoplasma capsulatum G186AR
XP_011116158 146 LVGASALTILGHASFLDRPIENAF 169 Dactylellina haptotyla CBS 200.50
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