Conserved Protein Domain Family
CobD_Cbib

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pfam03186: CobD_Cbib 
CobD/Cbib protein
This family includes CobD proteins from a number of bacteria, in Salmonella this protein is called Cbib. Salmonella CobD is a different protein. This protein is involved in cobalamin biosynthesis and is probably an enzyme responsible for the conversion of adenosylcobyric acid to adenosylcobinamide or adenosylcobinamide phosphate.
Statistics
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PSSM-Id: 397344
Aligned: 492 rows
Threshold Bit Score: 92.129
Threshold Setting Gi: 357423094
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Osc7112_6004   9 LILAAVLDYSIGDPWGWPHPVQAMGWAIDRYTRLVfNiwknpagkmpeagdrpagdrpKlllrcAGTILAIGLIVGSYTV 88  Oscillatori...
WP_014846182      10 IVIGMVADQVFADPQKH-HPVAWFGSWATRVEKTThAds------------------rA-----AGAVFTALAVAPVLAG 65  Pseudopropi...
CBL56739          31 LISAVTADRLIPDPANPWHPVAWFGTWAGWLEKKMwRds------------------vG-----QGAAYLVVALLPVATL 87  Propionibac...
Q6AAP7            20 LGLGIIADHIVPDPQTH-HPVAVFGAAVARLEKTMyAds------------------tR-----RGTLFTVTCLTPLAVI 75  Cutibacteri...
P9WP93            13 VLIGCLLDVVFGDPKRG-HPVALFGRAAAKLEQITyRdg------------------rV-----AGAVHVGLLVGAVGLL 68  Mycobacteri...
jgi:Tpau_2715      7 LALGVLADEVFGDPRSY-HPVAGFGTAAVAVERVMyAps------------------kV-----RGIAYTAILVGGATTL 62  Tsukamurell...
Q5YZB8            11 LVLGFALDRALGDPRRW-HPVAGFGSAALALESVTyAdr------------------rT-----AGLVHESVAVGAVVGF 66  Nocardia fa...
Q0SHH1            43 LLLGFAGDRVFADPARW-HPVAGFGRTAMALEKVTyRds------------------rP-----AGILHVAVLVGGAAGL 98  Rhodococcus...
WP_005512384      18 LVLGYLADRALGDPRRL-HPVAGFGLAAMALEKRTyAds------------------rL-----SGATHTAILVGATAAL 73  Rhodococcus...
WP_012834824      21 LAAGYALDRIAADPRRG-HPVAVFGRLAADAERHLyRds------------------rW-----AGTLFVAGTVGPAVLG 76  Gordonia br...
jgi:Osc7112_6004  89 SWSIVQaaswvhpllgialdTILLASCFAGRSLRAAAEDVLAPFnvgDLVKARERLSLYVGRDTENLSEPEILRALLETV 168 Oscillatori...
WP_014846182      66 GMLVERvsarhgw-irvaatAAATWAALGARRLADEGRIMADRLvggDLDAAREQLPNLCGRDPRFLDAEGLGRATVESM 144 Pseudopropi...
CBL56739          88 GVAVEAatrrhpl-ahatatAAAGWLVIGSQSLATEGEQMADELegdDLSAARDRLPHLCGRIPDTMPEQELARGTIESL 166 Propionibac...
Q6AAP7            76 GGAVDRltrnrpa-lriattALATWAVVGSASLAREGRAMAGHLangDLVAARKRLPHLCGRAPDALDAAEIARGAVESM 154 Cutibacteri...
P9WP93            69 GAALQRlpgrsw---pvaatATATWAALGGTSLARTGRQISDLLerdDVEAARRLLPSLCGRDPAQLGGPGLTRAALESV 145 Mycobacteri...
jgi:Tpau_2715     63 GYALRnvp---------gatALGTWAVVGGAGLRGVGSDLGRHLevgDDTAARGLLPSLCGRDPSVLDVAGMARAATESV 133 Tsukamurell...
Q5YZB8            67 GLVLRRggv--------aatALATWTALGGRSLARTGRAMARRLesgDVDGARALLPSLCGRDPAVLDADGLARAALESI 138 Nocardia fa...
Q0SHH1            99 GVAATRmarrggwpgevagtAVATWAVLGGTSLGRTGSSMAAHLevdDLAAARALLPSLCGRDPSVLGVDGLTRATLESV 178 Rhodococcus...
WP_005512384      74 GVLAERsgrragwvgqtavtAAATWTVLGGTSLADTGRTMARHLdadDLESARALLPSLCGRDPSVLDADGLARASLESV 153 Rhodococcus...
WP_012834824      77 GRVLRDvcrsap--arclatAAVTWSVLGGTSLTRVGAQVADALdagDIVAARALVPSLCGRDPESLDAAGICRAAVESL 154 Gordonia br...
jgi:Osc7112_6004 169 TENAVDGVTAPLFYALLgfagphlllsvtagqidpnsmwasaIVPLAIAYKAASTLDSTIGYKEAPYTDLGWFSAKLEDV 248 Oscillatori...
WP_014846182     145 AENTNDAGVCTILWGALa------------------------GVPGILTHRALNTLDAMVGHRNQRYGRFGTASARADDA 200 Pseudopropi...
CBL56739         167 AENTADSGVASLWWGSVa------------------------GIPGMLIHRASNTLDAMVGHHNEHFEHFGKCAARLDDG 222 Propionibac...
Q6AAP7           155 AENASDAAVASLWWGAVa------------------------GLPGLLVHRGANTLDAMIGHHNDRYEHFGKVAAYLDDV 210 Cutibacteri...
P9WP93           146 AENTADAQVVPLLWAASs------------------------GVPAVLGYRAINTLDSMIGYRSPRYLRFGWAAARLDDW 201 Mycobacteri...
jgi:Tpau_2715    134 AENTSDAAVAPLFWGALa------------------------GLPGLLGYRAANTLDAMVGYRNDRYADFGWASARLDDA 189 Tsukamurell...
Q5YZB8           139 AENTSDAAVGPLVWGAIa------------------------GVPGLLGYRAINTLDAMIGYRDERYRRFGWAAARTDDV 194 Nocardia fa...
Q0SHH1           179 AENTSDSAVGAFVWGAVa------------------------GIPGLFVYRASNTLDAMVGYRSPKYRNFGWAAARWDDV 234 Rhodococcus...
WP_005512384     154 AENTSDATVGALFWGAVa------------------------GVPGLLAYRASNTLDAMIGYRNDRYGRFGWAAARWDDV 209 Rhodococcus...
WP_012834824     155 AENTSDATVGPLVWGALg------------------------GIGGLIGYRAINTLDAMVGYRSPRYRNFGWAAARTDDI 210 Gordonia br...
jgi:Osc7112_6004 249 LTWIPCRLTVITLALisg-----kpIyIWQICQRDAVKDASPNSGWSECVYAAILGVQLGGTNSYr-GVLKHKPLLGePv 322 Oscillatori...
WP_014846182     201 AAWVPARLTGALACVcaplvggdvsR-AWRIMRRDGARHPSPNGGWCESAWAGALGVRLGGENRYg-DRVEFRPTLG-Dg 277 Pseudopropi...
CBL56739         223 LDWIPARLTGILGAIcapsvggrvvT-TARIVARDARNHPSPNGGWCESAWAGALGVQLGGRNVYpgGRVEHRGLLG-Dg 300 Propionibac...
Q6AAP7           211 VNWVPARFTGALAAGcastvggdrkT-TWRVVRAEHGHHPSPNGGWCESAWAAALGVQLGGRNVYygNRVEFRPLLG-Sg 288 Cutibacteri...
P9WP93           202 ANYVGARATAVLVVIcapvvggsprG-AVRAWRRDAARHPSPNAGVVEAAFAGALDVRLGGPTRYh-HELQIRPTLG-Dg 278 Mycobacteri...
jgi:Tpau_2715    190 LNYLPARLTGAVTVAaapvvdgapsD-AIRAWRNDAAKHPSPNAGVAEATAAGALGLRLGGRTQYa-HGVEQRPTLG-Dg 266 Tsukamurell...
Q5YZB8           195 ANLLPARLTGLLTAAlapvvggrprA-VLRAWRRDAGKHPSPNAGVAEAAMAGALGVRLGGRTRYr-HGTELRPTLG-Dg 271 Nocardia fa...
Q0SHH1           235 LNLLPARLTGALSVMaapavggspnE-AWEAWRRDASQHPSPNAGVAEASAAGALGISLGGRTEYa-HGVEMRPVLG-Sg 311 Rhodococcus...
WP_005512384     210 VNLAPARLAGALTVAaapvvggsprA-AVQAWRRDAAAHPSPNAGVAEASAAGALGVQLGGRTEYa-HGVEMRPTLG-Sg 286 Rhodococcus...
WP_012834824     211 ANLVPARLAGALTVVvgg----aprR-AAAAWRADAHAHPSPNAGVVESAFAGALGVRLGGPTVYp-HGTEDRPVLG-Ag 283 Gordonia br...
jgi:Osc7112_6004 323 HPITPPLICQALQLT 337 Oscillatoria nigro-viridis PCC 7112
WP_014846182     278 PRPTGPQVRRAAKLV 292 Pseudopropionibacterium propionicum
CBL56739         301 HRPRAGQVRDGARLV 315 Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Q6AAP7           289 TRPDADKTADAARLV 303 Cutibacterium acnes
P9WP93           279 RSPKVADLRRAVVLS 293 Mycobacterium tuberculosis H37Rv
jgi:Tpau_2715    267 RAPGPGDLARAAALS 281 Tsukamurella paurometabola DSM 20162
Q5YZB8           272 PAPTVADLRRAVRLS 286 Nocardia farcinica
Q0SHH1           312 PSPLPVDLDRAVRLS 326 Rhodococcus jostii RHA1
WP_005512384     287 PAPVIADLERAARLS 301 Rhodococcus hoagii
WP_012834824     284 APPTPDDLRATVRLS 298 Gordonia bronchialis
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