2WKN


Conserved Protein Domain Family
FmdA_AmdA

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pfam03069: FmdA_AmdA 
Acetamidase/Formamidase family
This family includes amidohydrolases of formamide EC:3.5.1.49 and acetamide. Methylophilus methylotrophus FmdA forms a homotrimer suggesting all the members of this family also do.
Statistics
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PSSM-Id: 397271
Aligned: 71 rows
Threshold Bit Score: 188.933
Threshold Setting Gi: 503170030
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2WKN_A                62 RDVDLSTVHFLSGPVGVKGAEPGDLLVVDLLDIGAR------------------------------------------DD 99 
WP_014825031          69 ITPTIRGGHEVTKPVYVEGAEVGDAIVIQIKSIQVTsiatssgtdeaqnerfigdpfvkvkcpgcgklhpptivqgigQE 148 Solibac...
jgi:Bsel_1905         46 itpclKGGHEVTKPVFVEGAEVGDAVAIRIKSIRVTsiatasgndapvdgrflgdpfvavkcpecgemnpqtvikgigQD 125 [Bacill...
Q5L060                46 ITPCIRGGHEVTKPVFVEGAEVGDAIAIKIKSIRVTsiatssgndkpmegrfvgdpfvavkcpqcgtmypetkiegigPE 125 Geobaci...
WP_013076505          49 ITPAIRGGHEVTRPVFVAGAEVGDAIAIRIQSIRVTsiatasgndrtvegsflgdpfcaakcpvcgtmypetriegigPH 128 Kyrpidi...
goetting:Curi_c07590  45 ITPALRGGHEVTRPVFVENAEIGDAVAIYIKSITVTssvassgnevaveknfvgdpfvagrcpncgtlypetklegigSA 124 Gottsch...
BAM01204              63 ITPAIRGGHEVTRPVAVAGAEVGDAIVIRIKDITVTslatssgndrimsgrflgdpyvagkcpqcgtlypktvlrgigQT 142 Caldili...
jgi:Cwoe_3284         54 ITPAIRGGHEVAQPVAVEGARVGDAIAIRIKDISVTslatssgndqamdgrfngdpycaavcpgcgdewpattldgigPT 133 Conexib...
jgi:Sthe_1570         51 ITPAIRGGHEVTQPVAVEGAEVGDAIAIRIKDIVVTsiatasgndqvmagrflgdpyvagrcpecgtlypetriegigPT 130 Sphaero...
jgi:Dshi_4177         52 iTPRLRGGHEVTTPVHVQGAEVGDGVAIRIRDITVTslatasghdsspegfclgdpyvaarcpvcdtvwpethvegigQD 131 Dinoros...
2WKN_A               100 S---------------LWGFNGFFSKQNGGGFL--DEHFPLAQKSIWDFHGMFTKSRH----------IPGVNFAGLIHP 152
WP_014825031         149 SvkcmtcgtdttpfkiSNGYTMTFNSKGNVGLTvgKEAARRIAQDSKNYMRTPENSVQnpitsfapsdLIGVLARMRPFV 228 Solibac...
jgi:Bsel_1905        126 AircencdadvtpfrfTNAYTMTFNDQKTVGITldKQGAEQVAHDGKSYMSTPENSVQnpivtfaphdLVGAIARVRPFL 205 [Bacill...
Q5L060               126 AircancgadvtpfvfTNGYTMTFDPNRQIGVTvhKEAAEHIARQGRYYMATPDNSVQnpivtfaphdLVGTVARLRPFL 205 Geobaci...
WP_013076505         129 SirctncgadaspfqfTNGYTIAFDENYELGVTlpRDAAERIAADGRQFMATPEHSIQnpivtfaphdIVGAVARVRPFL 208 Kyrpidi...
goetting:Curi_c07590 125 SvhcakcdeeiaafqfTNGYTIALNENKTIGVTltKEASEEAAKKAKSYMAVPDNSIQnpvvtfaphdIVGNISRLKPFI 204 Gottsch...
BAM01204             143 AvrcancgadaspftfTNGYTIVFDANRSVGITlhKEAAEAIAWEAKRYAALPDNSIQnpiltfaphdLVGLVARLRPFM 222 Caldili...
jgi:Cwoe_3284        134 AvrcarcgadatpftfTNGYTIAFDEQHAVGVTvgREAAERFAREAARAAALPDGSVQnpiltfaphdVVALATRLRPFM 213 Conexib...
jgi:Sthe_1570        131 AvrcvncgadatpfifTNGYTIAFDENRQVGVTlhQQAAESIAREAERYAALPENSIQnpiltfaphdLVGVVARMRPFL 210 Sphaero...
jgi:Dshi_4177        132 AvkcdscgnavtpfeiVHGYTVTFDETRSVGLTlpQEAAETLARDADHYAALPDASRQhsiltyapsdMPGTLVRMRPFM 211 Dinoros...
2WKN_A               153 GLIGCLPDPKMLASWNE----------------RETGLiATdpdripglanppnattahmgqmqgeardkaaaegartvp 216
WP_014825031         229 GQLGTTPSKAMPDSHNAgdfgtfligapheftmTEDELnIH--------------------------------------- 269 Solibac...
jgi:Bsel_1905        206 GQLGTTPSRPIPDSHNAgdfgqfligaphdyglTEDEL-ED--------------------------------------- 245 [Bacill...
Q5L060               206 GQLGTTPARPLPDSHNAgdfgqflinapheygiTKEQL-ED--------------------------------------- 245 Geobaci...
WP_013076505         209 GQLGTTPSRPMPDSHNAgdfgsfllgaphqyalTQEELdEA--------------------------------------- 249 Kyrpidi...
goetting:Curi_c07590 205 GQLGTTPSIPMPDSHNAgdfgsfllgapheyalTEEELlKH--------------------------------------- 245 Gottsch...
BAM01204             223 GQLGTTPSIPFPDSHNAgdfgsfligapheyglSAEQL-AH--------------------------------------- 262 Caldili...
jgi:Cwoe_3284        214 GQLGTTPSTTIPDSHNAgdfgsflvgaphryalTAQELqQH--------------------------------------- 254 Conexib...
jgi:Sthe_1570        211 GQLGTTPAIDMPDSHNAgdfgsflvgapheygiTVDQL-AH--------------------------------------- 250 Sphaero...
jgi:Dshi_4177        212 GQLGTCPSMAMPDSHNAgdfgaflvgaphdyaiTAEQLaEH--------------------------------------- 252 Dinoros...
2WKN_A               217 prEHGGNCDIKDLSRGSRVFFPVYVDGAGLSVGDLHFSQGDGEItfCG-AIEMAGWVHMKVSLIKGGmakyGIKNPIFKP 295
WP_014825031         270 --RTDGHMDINRVREGAVVICPVKVPGGGVYVGDMHAMQGDGEI--AGhTTDVSGIVQLQVSVLKKV----NLDGPILLP 341 Solibac...
jgi:Bsel_1905        246 --RTDGHMDINRAREGAIVIAPVKVEGGGVYLGDMHAMQGDGEI--AGhTTDVSGIVTLQVNVIKGL----KLEGPVILP 317 [Bacill...
Q5L060               246 --RTDGHMDINRVREGAVLICPVKVRGGGVYLGDMHAMQGDGEI--AGhTTDVSGIVTLQVKVIKGL----TIDGPILLP 317 Geobaci...
WP_013076505         250 --RTDGHMDIARVREGAILVCPVKVPGGGVYLGDMHALQGDGEI--AGhTCDVSGVVTLQVHVIKGA----NLEGPILIP 321 Kyrpidi...
goetting:Curi_c07590 246 --KTDGHMDINRAREGAIVICPVKVKGGGVYVGDVHAMQGDGEI--AGhTCDVSSVVTLKVKVIKNL----NIDGPIILP 317 Gottsch...
BAM01204             263 --RTDGHMDIDAVRAGAILICPVKTPGGGVYLGDMHALQGDGEI--AGhTCDVSGTVTLQVHVLKNL----PIDGPILLP 334 Caldili...
jgi:Cwoe_3284        255 --KTDGHLDVDAVRAGAILICPVKVDGGGVYMGDMHALQGDGEI--AGhTADVSGTVTLQVEVVKGL----GIDGPILLP 326 Conexib...
jgi:Sthe_1570        251 --RTDGHLDVDAVRAGAILICPVKAPGGGVYMGDMHALQGDGEI--AGhTCDVSGVVTLQVHVIKGL----NIDGPILLP 322 Sphaero...
jgi:Dshi_4177        253 --KTDGHMDIDAVRAGAIIVCPVKVPGAGVYMGDMHAGQGDGEI--AGhTMDVSGSVTLQVEVVKNY----PIDGPVLFP 324 Dinoros...
2WKN_A               296 ---------------------------------SPMTPnykdyLIFEGisvdeKGKqhylDVTVAYRQACLNAIEYLKkf 342
WP_014825031         342 nvedlpytakpftkee-kriarelaeefgvkqvEESFP-----LSVVG-----TGA----NLNVATENALERAAKLFE-- 404 Solibac...
jgi:Bsel_1905        318 veedlpylakpitkaereeakrlhagwsmqqplESSLP-----LSFVG-----TGA----TLNDATTNGLERAAMVLG-- 381 [Bacill...
Q5L060               318 vaedlpylakpltkke-keialdlaqswgvnklEESLP-----ISFVG-----TGA----NLNEATENGLQRAAKTLG-- 380 Geobaci...
WP_013076505         322 needlpylarpltese-kalakaqatkwgfdaiEETAP-----VSVVG-----SGA----TLNAATDNALERAARLFG-- 384 Kyrpidi...
goetting:Curi_c07590 318 veedlpylakplnvee-kkramelasewgieslENTAP-----ISFVG-----TGS----NLNEAIDNGLTRAAELFN-- 380 Gottsch...
BAM01204             335 vaedlpflakplsaee-karalaiarqwglealEESAP-----ISVIG-----TGP----DLNAATDNGLERAARLLE-- 397 Caldili...
jgi:Cwoe_3284        327 vaedlpflakpltase-raraaalgarygvaelEESLP-----ISVIG-----TGP----DLNSATDNGLARAAELLG-- 389 Conexib...
jgi:Sthe_1570        323 vaedlpflakpltaee-raraealaqawgvpalEESAP-----ISVIG-----TGP----DLNSATDNGLQRAADLLE-- 385 Sphaero...
jgi:Dshi_4177        325 leedlpplarpfteae-kakgdrlaakwgvkeiEPLAP-----ISVIG-----TAA----NLNDAIENGLARAATLLD-- 387 Dinoros...
2WKN_A               343 gysgaqayslLGTAPVQGH--ISGVVDV---PNACA 373
WP_014825031         405 ----------LTVEEVRNRatITGGIEIgrhPGVVT 430 Solibacillus silvestris
jgi:Bsel_1905        382 ----------TSVPEVMNRatVTGAIEIgrnPGVVT 407 [Bacillus] selenitireducens MLS10
Q5L060               381 ----------ISVPEVMNRatITGAIEIgrhPGVIT 406 Geobacillus kaustophilus
WP_013076505         385 ----------MSVPEVKNRatITGSIEIgrhPGVVT 410 Kyrpidia tusciae
goetting:Curi_c07590 381 ----------ISVPEVKNRttINGAVEIgryPGTat 406 Gottschalkia acidurici 9a
BAM01204             398 ----------MSVPEVKNRatITGAIEIgrhPGVVQ 423 Caldilinea aerophila DSM 14535 = NBRC 104270
jgi:Cwoe_3284        390 ----------MSVPEVMNRatIAGAIEIgrhPGVVQ 415 Conexibacter woesei DSM 14684
jgi:Sthe_1570        386 ----------MTVPEVKNRatITGAIEIgrhPGVVQ 411 Sphaerobacter thermophilus DSM 20745
jgi:Dshi_4177        388 ----------MTVAEVRNRatINGAIEIgraPGVIQ 413 Dinoroseobacter shibae DFL 12 = DSM 16493
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