1VPM,5V10,1S5U,2PZH,2EGI,5WH9,4K00,1NJK,3QY3,2O6T,2F0X,2FS2,3S4K,4QDB,4K4C,1SBK,2B6E,4K02,3NWZ,1ZKI,2HBO


Conserved Protein Domain Family
4HBT
?
pfam03061: 4HBT 
Click on image for an interactive view with Cn3D
Thioesterase superfamily
This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT (EC 3.1.2.23) which catalyzes the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl-CoA thioester hydrolases. Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyze the hydrolysis of other long chain fatty acyl-CoA thioesters.
Links
?
Statistics
?
PSSM-Id: 427116
Aligned: 125 rows
Threshold Bit Score: 44.9386
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
1VPM_C  38 LGTIFGGKV----LAYIDEIAALTAXKHANs----------aVVTASIDSVDFKSSATVGdALELEGFVTHTGRTSXEVY 103 Alkalihalobacillus ha...
Q9I4Y1  19 EGIVYTPRFsyfvLEAVQEALGVWLGGPGLrtll----gfriLPPARAFSLEFLHPVTWDdELTMQVGVSNVGTHSFSFS 94  Pseudomonas aeruginosa
Q9L110  29 LGLLHNARY----PVMVERAWTELWAGHGVrfegdweaagdaCNAVRELTIGYEAPVTRPgAYAVHLWLDRLGTTGLTYG 104 Streptomyces coelicolor
O07408  31 FGHLNNAVY----YQLFDTAINAWINTSTGvdpl----ampvLGIVAESGCRYFSELRFPeSLMVGLAVTRLGRSSVTYR 102 Mycobacterium tubercu...
Q9DCP4  76 NSHVNNAVY----YSYFDTVISHYLIRYCGlktsl--ltspqVGFMVTNQCKFHTPISFPqTPLAALAVEKVGRSSVCYR 149 house mouse
2O6T_I  30 YGHVNNVTY----YAFFDTAVNTYLIERGGldiq----ggevIGLVVSSSCDYFAPVAFPqRIEMGLRVARLGNSSVQYE 101 Pseudomonas aeruginosa
P11469  34 FGHMNNVTP----FIYFEEVRISYFKKLNMmsen-----kqtMTVVASQQCDYLRQVMPYeELRIYVKTSAVGSSSLTLH 104 Bacillus subtilis sub...
Q9K8B6  33 FGHLNNTKT----FVYFEEARTDFFKSLGFfklwtn-peyegMIVVADLQCDYQRQVFFDdRLTVWVKPANIGSSSVDLH 107 Bacillus halodurans
Q9HTM6  26 QGIVFNGNY----LTYLDVATTEYYRQLGMsypadl-lrgggDLFAVKSTLEYRAPAHFDdWLDIGTRVARLGRSSLVFE 100 Pseudomonas aeruginosa
Q0KBD3  22 qSIVFNAHY----LTYCDICVTEYWRALGIrypedvlhahgvDIFVVKSTLEYHASARFDdELEIRGRMSRLGRSSMLFR 97  Cupriavidus necator H16

1VPM_C 104 VRVHSNNLLTGE 115 Alkalihalobacillus halodurans C-125
Q9I4Y1  95 VEGRLSPDVVAF 106 Pseudomonas aeruginosa
Q9L110 105 FRFCSADGATTY 116 Streptomyces coelicolor
O07408 103 LGVFKEPDDAGV 114 Mycobacterium tuberculosis
Q9DCP4 150 LALFPPKPTKEL 161 house mouse
2O6T_I 102 LALFLEGQREAC 113 Pseudomonas aeruginosa
P11469 105 YLGENLEGEPCF 116 Bacillus subtilis subsp. subtilis str. 168
Q9K8B6 108 YMIKNSTGHICM 119 Bacillus halodurans
Q9HTM6 101 LGIWRDEQLLTV 112 Pseudomonas aeruginosa
Q0KBD3  98 VEMFRGDEHLIt 109 Cupriavidus necator H16
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap