Conserved Protein Domain Family
Pyr_excise

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pfam03013: Pyr_excise 
Pyrimidine dimer DNA glycosylase
Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.
Statistics
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PSSM-Id: 397243
Aligned: 97 rows
Threshold Bit Score: 53.056
Threshold Setting Gi: 1407994291
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
YP_004324221   1 MNIFVT--------DPcprksaQVLPDKHVVKMPLETCQMLSIVFshwyydwgddllkkkdgtpyktskgafrNHPCTQW 72  Synechococcus p...
AHH02019       2 VNTFIL--------CSdfsesaSLLDDKRLFKQCVEARQIISILEesnls------------------kkgfsNHPATKQ 55  Pithovirus sibe...
AWY04507       1 MMTWMP--------NKslfdsaEALELDQLAVATVEGASLFNEMLygeptd-----------------gqmkaPVPLIGM 55  Microbacterium ...
CEM10813       5 IVTYLP--------YAdyrrcaECMRKNDLQLQIDQSLDIFEQIStnafa------------------rsrydGHPCVEM 58  Vitrella brassi...
AWY05216       1 MQTFLVa--------------pRNLDPKRLANQINECQSIWVALTegr----------------------gyiNHPATLM 44  Gordonia phage ...
AWY06168       1 MQTFICdryefgadRAsfhdglRHLDDKRLGKQRLEAKQIYHALTake----------------------gwvHHPATKM 58  Gordonia phage ...
SNV07499       1 MQIFRV--------SPnpnvsaEFLDNRRLSKQVLELYQIIRVCLgelgaiq---------------tgtgyrNHPVVKA 57  Staphylococcus ...
WP_072710301   1 MQIFRV--------SPdhedsaKFLDNRRLSKQVLELYQIIRVCLgemglve---------------vntrylHHPVVKV 57  Salinicoccus al...
OAO32615       1 MQIFRV--------SPnhevsaKYLDNRRLSKQILELYQIIRVCLahmelie---------------gntkyiYHPIVQH 57  Staphylococcus ...
WP_002472354   1 MQIFRV--------SSdhhqsaQFLDNRRLSKQVLELYQIIRVCLaemniie---------------gntrylSHPIVKH 57  Staphylococcus ...
YP_004324221  73 AAKSly-nTAWLIQHGCALSTEYTHR--YGKEHGCRD 106 Synechococcus phage S-SSM7
AHH02019      56 WIGY----LDGLKYYFNCHLDEVFRRgrWNVKVMTIY 88  Pithovirus sibericum
AWY04507      56 WAGY----EAALAAYVAACATTLVR---YGVSATNRA 85  Microbacterium phage AnnaSerena
CEM10813      59 WRAH----VPALVKYIRTLHGVYVEKg-YKTHRDDEM 90  Vitrella brassicaformis CCMP3155
AWY05216      45 WDGY----LIALAQYAVAMCEEHERRt-MSTHALHEN 76  Gordonia phage Margaret
AWY06168      59 WTGF----TDALLEYGVSCCLEWRSRg-HTDTMLDWF 90  Gordonia phage Suzy
SNV07499      58 VYNEgnpyLWGALEIMDAMNREHLRRg-GNQSEHFKN 93  Staphylococcus piscifermentans
WP_072710301  58 VYNDgrpyLPDTLVMLEAMDEEHMRRg-GKRSLEFRD 93  Salinicoccus alkaliphilus
OAO32615      58 VYNDgnpyIIDTFQLLKEMNKEHIRRg-GKRSESFKQ 93  Staphylococcus lentus
WP_002472354  58 VYHDgkpyLLDAYALLRVMDEEHQQRg-GKRSSDFRE 93  Staphylococcus pettenkoferi
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