6GUE,1W98


Conserved Protein Domain Family
Cyclin_C

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pfam02984: Cyclin_C 
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Cyclin, C-terminal domain
Cyclins regulate cyclin dependent kinases (CDKs). Human CCNO is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the C-terminal domain.
Statistics
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PSSM-Id: 397230
Aligned: 237 rows
Threshold Bit Score: 35.6769
Threshold Setting Gi: 147636834
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6GUE_B 139 PTINQF----LTQY-FLH---------------QQpA--NcKVESLAMF----------LGELSLIDADpYLKYLPSVIA 186 cattle
Q8LPW3 178 VTPISFldhiVRRLgLSN------------------HlhW-DFFKKCEA----------MILYLVADSR-FVCYKPSVLA 227 common sunflower
P42753 189 ITPISFvdhiIRRLgLKN------------------NahW-DFLNKCHR----------LLLSVISDSR-FVGYLPSVVA 238 thale cress
Q9SN11 188 VTPISFfdhiIRRYsFKS------------------HhqL-EFLSRCES----------LLLSIIPDSR-FLSFSPSVLA 237 thale cress
P42751 184 VTPFDF----ISFFaYKId-------------pSG-TflG-FFISHATE----------IILSNIKEAS-FLEYWPSSIA 233 thale cress
Q9SNV2 176 ISPFCY----LSFFaLKId-------------pTG-TytG-FLTSRAKE----------IILSTVQETS-LIEYRPSCIA 225 snapdragon
O15995 255 ITVNTW----LNAF-MQIcnaeeianrktnfhfPS-YssT-EFV-QVAQ----------LLDVCTLDIG-SMDFDYSILA 315 Hemicentrotus pulcher...
Q5U4W4 240 VTAISW----LNLY-LQV---------------SSlKdhP-KLL-LPQYsqeqfihvaqLLDLCILHHT-SLNFQYRILA 296 African clawed frog
Q5ZMH4 247 VTIISW----LNLY-LQV---------------DAlKdvP-KVL-LPQYsqekfiqiaqLLDLCILDVN-SLDFQYRTLA 303 chicken
Q9Z238 241 VTVISW----LNLF-LQV---------------DAvKdvP-KVL-LPQYsqetfiqiaqLLDLCILAID-SLEFQYRILA 297 house mouse
6GUE_B 187 AAAFHLALYTV------TGQS---WP----ESLVQKT-GYTLETLKPCLLDLHQTY--LRAPQHAQ-QSIREKYKNSK-- 247 cattle
Q8LPW3 228 TATMLCVVEEI------DPTNsigYK----SQLLDLL-KTTKDHINECYKLVMDLSy-DNHNKGKRdENERTIYPVSPag 295 common sunflower
P42753 239 AATMMRIIEQVdp---fDPLS---YQ----TNLLGVL-NLTKEKVKTCYDLILQLP------VDRI--GLQIQIQSSK-- 297 thale cress
Q9SN11 238 TAIMVSVIRDLkm---cDEAV---YQ----SQLMTLL-KVDSEKVNKCYELVLDHS----PSKKRM-MNWMQQPASPIgv 301 thale cress
P42751 234 AAAILCVANELpslssvVNPH---------ESPETWCdGLSKEKIVRCYRLMKAMA--IENNRLNT-PKVIAKLRVSV-- 299 thale cress
Q9SNV2 226 AATMLSSANDL--------PK---FSfitaQHAEAWCdGLHKDNIASCIKLIQGVE--SNNRPKKQ-PKVLPQLR----- 286 snapdragon
O15995 316 ASALYHVTNE--------------------EVTLSVT-GLKWDDIAACVQWMSTFAmtIREVGVAQlKNFKNIYAGDA-- 372 Hemicentrotus pulcher...
Q5U4W4 297 AAALYHCTSI--------------------EVVTKAT-GLEMDNISECVHWMAPFVrvVKRSLPLK-LKVFKKVAPED-- 352 African clawed frog
Q5ZMH4 304 AAALCHYTST--------------------EVVKKAS-GLDWDNISECVEWMVPFVnvARKVS-VK-LKHFKKVAVED-- 358 chicken
Q9Z238 298 AAALCHFTSI--------------------EVVKKAS-GLEWDDISECVDWMVPFVsvVKSVSPVK-LKTFKKIPMED-- 353 house mouse
6GUE_B 248 YHGVSLLNPP 257 cattle
Q8LPW3 296 FIG-FMCHES 304 common sunflower
P42753 298 KRKSHDSSSS 307 thale cress
Q9SN11 302 FDA-SFSSDS 310 thale cress
P42751 300 RAS-STLTRP 308 thale cress
Q9SNV2 287 VMTRASLASS 296 snapdragon
O15995 373 HNI-QTHCSS 381 Hemicentrotus pulcherrimus
Q5U4W4 353 MHNIQTHTNF 362 African clawed frog
Q5ZMH4 359 CHNIQTHTNY 368 chicken
Q9Z238 354 RHNIQTHTNY 363 house mouse
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