Conserved Protein Domain Family
Amelogenin

?
pfam02948: Amelogenin 
Amelogenin
Amelogenins play a role in biomineralisation. They seem to regulate the formation of crystallites during the secretory stage of tooth enamel development. thought to play a major role in the structural organisation and mineralisation of developing enamel. They are found in the extracellular matrix. Mutations in X-chromosomal amelogenin can cause Amelogenesis imperfecta.
Statistics
?
PSSM-Id: 397207
Aligned: 3 rows
Threshold Bit Score: 116.692
Threshold Setting Gi: 1061019355
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_003228746  21 PLPQHPGYINFSYEVMTPLKWYQSLIGHQYPRYGFEPMGGWMHHAAGPTMHQTTFQSHPSvhs-tlHQMQPPHPALNPHM 99  green anole
AAI70913      21 PHPQHPGYVNFSYEILSPLKWYQSMMKHQYPNYGYEPMSGWLQNPVVPAPPMMPQQQHPS------QHVVPKLPPHHPFL 94  tropical clawed...
XP_017823836  21 PHPGHPGYINFSYEVLTPLKWYQSMIRPAYPSYGYEPMGGWLHHQIIPVLS----QQHPPthtlqpHHHIPVVPAQQP-V 95  white-tufted-ea...
XP_003228746 100 QPsgHNPFGSMPgqNTLMPqfqpahg--gpihhpFQPHAGe-HPMHPQQTGNP----VHPMHPQQPANPNS---PIYPVQ 169 green anole
AAI70913      95 IP--QQPVVPVP--HPVIP---------------LTPQHT--HQLKPTYLSNPdsanTQPLEPFKPDHENKnghPMFPLQ 153 tropical clawed...
XP_017823836  96 VP--QQPMMPVPgqHSMIPtqhhqpnlpppaqqpFQPQTVqpQPHQPMQPQSP----VHPMQPLPPQPPLP---PMFPMQ 166 white-tufted-ea...
XP_003228746 170 QLPPLISDTPLESWPPADKTKQEEVD 195 green anole
AAI70913     154 PLPPLFEERPQEPWQAAGNTNQEELD 179 tropical clawed frog
XP_017823836 167 PLPPMLPDLPLEAWPATDKTKREEVV 192 white-tufted-ear marmoset
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap