4KS0,1VP8,1T57


Conserved Protein Domain Family
PK_C

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pfam02887: PK_C 
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Pyruvate kinase, alpha/beta domain
As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Statistics
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PSSM-Id: 397155
Aligned: 638 rows
Threshold Bit Score: 33.2222
Threshold Setting Gi: 335359844
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4KS0_A         399 EAVCSSAVNSVYEVRAKALLVLSNSGRSARLASKYRPD--CPIICATT-------------------------RMRT--- 448 Trypanosoma c...
WP_012744561    13 DAVLDLVFETAVKEGIRHVVLPSTRGKVATKALEMVPEd-IDLVIVTHsvgfrksgv--------defdpevrKLYEntr 83  Kosmotoga
jgi:Thein_1666  14 EAALKIAFKAFKERGLKHIVIASTFGDTGLKAAELFAGkeANLVVVTHnvgfrepgk--------ieitqemrAKIEslg 85  Thermodesulfa...
CCQ33631        10 EELLDRAKTYAEDQDVDAVCVASTSGETGAKAAERFGE---DLVVVGHsygfdeene--------qeldadhvEAIEaag 78  Halorhabdus t...
WP_012309106    21 ERVLLAAKSRCEERGIKKVVIASETGRSAVKALEIFRDtgVKLIVVTHypsktwgprgdipiglrrkeyaetlRKLEeng 100 Candidatus Ko...
BAI61262        18 NTTLKTVREWALKYNIKRVLVPSKSGQTAQKAYNLFKNtgIILTIVGTdpnif---------------sseilAQLRsng 82  Methanocella ...
jgi:Mpal_1128   18 EAVLAIVDERLKEGDIKNVVVASTSGATGVTFAQALGKk-TNLVIISTkpgsktpgv--------wefdpaneKKIKrlg 88  Methanosphaer...
BAF59142        12 RATVEAALKRAGELGLKHIVVASCSGKSAELLLGRAGD--FNITCVTHqvgfynpge--------dempaearKKLTdgg 81  Pelotomaculum...
Q2RFJ3          14 EATVKLALKRARELGLKDVVIPSVSGYTANLCLGIND---LNIVCVTHqagfkkpge--------iemdtairQRLEdgg 82  Moorella ther...
Q2LV38          23 EAVLEAVASRAEELSIGKVLVATCSGETALKAKKILKTs-IQLIAVSHvtgfakpdf--------qemtdqkrKELEtlg 93  Syntrophus ac...
4KS0_A         449 -------------CRQLT-ITRSVDAVFyDAerygedenkekrVQLG----VDCAKK---------KGYVVPGD--LMVV 499 Trypanosoma c...
WP_012744561    84 hkilttthlfrglEGYFYkKFGGVYPPQ-FFaa---------aLRLfg-egTKVAVEialm--aadAGLIPIDQ--WVIS 148 Kosmotoga
jgi:Thein_1666  86 akvytgtmvlrniGTAIReLQQ--YSQQdLIan---------tLRLfg-qgIKVCVEialm--acdAGLVPP-E--DVIT 148 Thermodesulfa...
CCQ33631        79 gdvfvgpmafsnvGSAIAeR-GGYSTHE-VIad---------vLRLfg-qgTKVAVEsplm--acdAGLVDSGA--RVLS 142 Halorhabdus t...
WP_012309106   101 vrivqgtrpfappSRCINwDY--PTPEA-IIdk---------tLEVfg-agTKIAIEvvlm--atdAGEVEPGE--EVIS 163 Candidatus Ko...
BAI61262        83 tkv----vfykdvPYTYTq----------DMkt---------aYRRmg-egFKVAVElgiiaayleEGDIN-----DVIT 133 Methanocella ...
jgi:Mpal_1128   89 grvirhthalsglEKSFTeRFSGISHSE-ILae---------sLKTLfspgTKVGVEigim--aldSGAITLEKtiVVGG 156 Methanosphaer...
BAF59142        82 irvltathlmaglDRACRnKFGGVYPSE-IVas---------aLRIlg-qgVKVCVEiavm--aldAGAIPYGT--EIVS 146 Pelotomaculum...
Q2RFJ3          83 ikvlttthllaglDRALRfSFQGIYPAE-IIan---------tLRLfg-qgTKVAVEvacm--aldAGLIPAGV--DIVS 147 Moorella ther...
Q2LV38          94 vpvltaqhafgglGRAIRnKFGTYQIDE-IMaf---------tLRVfg-qgTKVAIElalm--aadAGLVRTDE--DIIS 158 Syntrophus ac...
4KS0_A         500 VHADHKvkgyPNQTRII 516 Trypanosoma cruzi strain CL Brener
WP_012744561   149 AGGTGKg---LDTAYIL 162 Kosmotoga
jgi:Thein_1666 149 VAGTARg---ADTVAII 162 Thermodesulfatator indicus DSM 15286
CCQ33631       143 IAGTGSg---ADTALLV 156 Halorhabdus tiamatea SARL4B
WP_012309106   164 CAGTYKg---LDTALVV 177 Candidatus Korarchaeum cryptofilum
BAI61262       134 LGGTKKg---VDTALVI 147 Methanocella paludicola SANAE
jgi:Mpal_1128  157 TGATGRg---ADTALVV 170 Methanosphaerula palustris E1-9c
BAF59142       147 LGGTAEg---LDTALVI 160 Pelotomaculum thermopropionicum SI
Q2RFJ3         148 LGGSSEg---VDTALVL 161 Moorella thermoacetica ATCC 39073
Q2LV38         159 VGGTGSg---ADTALVI 172 Syntrophus aciditrophicus SB
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