1N7Q,1HM3,2WCO


Conserved Protein Domain Family
Lyase_8_C

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pfam02884: Lyase_8_C 
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Polysaccharide lyase family 8, C-terminal beta-sandwich domain
This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
Statistics
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PSSM-Id: 397152
Aligned: 76 rows
Threshold Bit Score: 50.6961
Threshold Setting Gi: 81454035
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1N7Q_A                  649 IENNETLQSVYDAKQGVWGIVKYDD-SVSTI-SNQFQVLKRGVYTIR--KEGDEYKIAYYNPETQESAPD 714  Streptococcus...
jgi:Cphy_0932           641 LENSKRLQAVSKNDFSVVEGVFFDSeKTLKMkDIEITVSQPCALLLQ--QEEDGYRIAVCDAEQKPELKE 708  Lachnoclostri...
CDB11486                726 LQNDTLVQAVRTNDRSVTQAVFYPGnKGLKAkGISLQTSVPCAVMIQ--QKDGKQTISVTDAAMDANlke 793  Bacteroides s...
CDA75452                725 MRNDIGVQAIRTKDKTIVQAVFYPGnAELKYkDLKLSVSAPCAVMIQ--KLGGKYRISVTDATMNADLKS 792  Bacteroides s...
CDB11858                845 LLCNDTVHAVRDAQTGITAYAAFDSvSLS---DDELLLRLPAEAMIMyrHVNGGIRISVCDPNLNISAKT 911  Bacteroides s...
Q8DZB2                 1004 LENSSKQQVIYDKNSQTWAVIKHDN-QESLI-NNQFKMNKAGLYLVQ--KVGNDYQNVYYQPQSMTKTDQ 1069 Streptococcus...
bgi:05SSU1212            42 LHQDRDLQVVYDQEQNVWGVVKYTD-TAYKL-TDDITLTDSGLYTIQ--KVEGGYRIAFYNPSTRTVKNG 107  Streptococcus...
jgi:Cycma_4185          614 LSNTKELQAVKNKEEQEVQAVFYQSgNLLLEnKLNLKMDSAGIILLQl-LHGKVHSMSISDPTRKLKEIT 682  Cyclobacteriu...
jgi:Runsl_2790          607 LSNTPDLQAVKHRNLGIIQLAFYKNgEVEIAkGAKLRMDSQGMAMLKl-NGNRLKELTLADPSRKLSRMs 675  Runella slith...
PRJNA61269:NIASO_08255  589 IQNNQNIQVAEDVEHLISGFVFVKEgAVTSEtFGKLSVDIPAVLLLS--KKGSQIDLSIADPTHQQKTAR 656  Niabella soli...
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