2L6Q


Conserved Protein Domain Family
gpW

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pfam02831: gpW 
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gpW
gpW is a 68 residue protein known to be present in phage particles. Extracts of phage-infected cells lacking gpW contain DNA-filled heads, and active tails, but no infectious virions. gpW is required for the addition of gpFII to the head, which is, in turn, required for the attachment of tails. Since gpFII and tails are known to be attached at the connector, gpW is also likely to assemble at this site. The addition of gpW to filled heads increases the DNase resistance of the packaged DNA, suggesting that gpW either forms a plug at the connector to prevent ejection of the DNA, or binds directly to the DNA. The large number of positively charged residues in gpW (its calculated pI is 10.8) is consistent with a role in DNA interaction.
Statistics
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PSSM-Id: 397116
Aligned: 5 rows
Threshold Bit Score: 81.8545
Threshold Setting Gi: 357380313
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2L6Q_A              1 MVr----QEELAAARAALHDLMTGKRVATVQK----DGRRVEFTATSVSDLKKYIAELEVQTGMTQRRRG 62  Escherichia virus La...
CASKLGSI:C427_2421  5 EQ-----INQLAEAQAARHKLMTGTAVVKVTK----DGMTVEYTQGSLRQLTNYIETLNQIVNDTGKRRP 65  Paraglaciecola psych...
Q8ZMZ4              1 MAt----ITELQEARVALHDLMTGKRVATVQK----DGRRVEFTATSVGDLKKYVAELEASL-CNGRRRA 61  Salmonella enterica ...
Q5FNH7             21 glttaqlQANLAAAQQAYNDLMIGGKPVAVSYsqvnGSRSVTYTAANKTDLLQYIQLLQKQLGIS--RRR 88  Gluconobacter oxydans
WP_014188166        1 MTdvtilEAWLADARAAHHALRIGQQKVSVRF----GDRVVEYAPANATQLASYIASLERQIAAAKGRRG 66  Azospirillum lipoferum
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