4C2K,5F0V,4O99,4WYR,1PXT,2F2S,5XYJ,5LP7


Conserved Protein Domain Family
Thiolase_C

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pfam02803: Thiolase_C 
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Thiolase, C-terminal domain
Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Statistics
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PSSM-Id: 397094
Aligned: 21 rows
Threshold Bit Score: 153.952
Threshold Setting Gi: 1174680
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4C2K_A       293 FTPLARIVGYFVSGCDP-SIMGIGPVPAISGALKKAGLS-LKDMDLVEVNEAFAPQYLAVERSLDLDI------------ 358 human
Q60587       332 YKPKAYLRDFIYVSQDPkDQLLLGPTYATPKVLEKAGLT-MNDIDAFEFHEAFSGQILANFKAMDSDWfaqnymgrktkv 410 Norway rat
P21775       298 LPILGVLRSYAVVGVPP-DIMGIGPAYAIPAALQKAGLT-VNDIDIFEINEAFASQALYCVEKLGIPA------------ 363 Norway rat
1PXT_B       269 LPVLGRYIDFQTVGVPP-EIMGVGPAYAIPKVLEATGLQ-VQDIDIFEINEAFAAQALYCIHKLGIDL------------ 334 baker's yeast
Q05493       291 QPILAKFVHCKTVGVPP-ELMGIGPAYAIPAVLEDLGLT-VNDVDVFEINEAFASQALFSIQHCGIDE------------ 356 Yarrowia lipoly...
EER36328     287 ypIVGKYVLCSTAGVPP-EIMGVGPAYAIPEVLKRTGLT-VEDIDVFEINEAFAAQCLYSAEQVNVPE------------ 352 Candida tropica...
2F2S_C       285 VTPLARIVAFADAAVEP-IDFPIAPVYAASMVLKDVGLK-KEDIAMWEVNEAFSLVVLANIKMLEIDP------------ 350 human
5XYJ_A       284 LKPLAIIKGWGEAAHQP-ADFTWAPSLAVPKALKHAGIEdINSVDYFEFNEAFSVVGLVNTKILKLDP------------ 350 Saccharomyces c...
XP_002547278 274 LKPLAKVSGWGEAARTP-FDFTIAPALAVPKAIKHAGLS-LDKVDFFELNEAFSVVGLANAELVNIPL------------ 339 Candida tropica...
5LP7_F       270 KRPLATILGFSTTGMPA-HELAAAPGFAINKLLKKNGLT-VQDIDLFEVNEAFASVVLTCEKIVGFDL------------ 335 Bacillus subtil...
4C2K_A       359 -----SKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRG-GKYAVGSACIGGGQGIAVIIQS 415 human
Q60587       411 gapplEKFNIWGGSLSLGHPFGATGCRLVMAAANRLRKDG-GQYALVAACAAGGQGHAMIVEA 472 Norway rat
P21775       364 -----EKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGrRAYGVVSMCIGTGMGAAAVFEY 421 Norway rat
1PXT_B       335 -----NKVNPRGGAIALGHPLGCTGARQVATILRELKKD---QIGVVSMCIGTGMGAAAIFIK 389 baker's yeast
Q05493       357 -----SKVNPRGGAIAIGHPLGATGARQFATLLSELKESGk-KVGVTSMCIGTGMGAASLVVA 413 Yarrowia lipolytica CLIB122
EER36328     353 -----EKLNINGGAIALGHPLGETGARQYATIIPLLKP---GQIGLTSMCIGSGMGSASILVr 407 Candida tropicalis MYA-3404
2F2S_C       351 -----QKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ---GEYGLASICNGGGGASAMLIQK 405 human
5XYJ_A       351 -----SKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEG-GKIGVAAICNGGGGASSIVIEK 407 Saccharomyces cerevisiae S288C
XP_002547278 340 -----EKLNVYGGAVAMGHPLGCSGARIVVTLLSVLTQEG-GRFGAAGVCNGGGGASAIVIEK 396 Candida tropicalis MYA-3404
5LP7_F       336 -----EKVNVNGGAIALGHPIGASGARILMTLVYELKRRG-GGLGVAAICSGAAQGDAVLVQV 392 Bacillus subtilis subsp. subtili...
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