3HJA,1HDG,2EP7,3RVD,2YYY,2XF8,6OK4


Conserved Protein Domain Family
Gp_dh_C

?
pfam02800: Gp_dh_C 
Click on image for an interactive view with Cn3D
Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
GAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. C-terminal domain is a mixed alpha/antiparallel beta fold.
Statistics
?
PSSM-Id: 397092
Aligned: 47 rows
Threshold Bit Score: 138.878
Threshold Setting Gi: 3122123
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3HJA_A        179 LAPLAKVLHESFGIEQGLMTTVHAYTNDQRILD-LPh-SDLRRARAAA--LSIIPTSTGAAKAVGLVLPELKGKLNGTSM 254 Borreliella bu...
O28542        147 LTRLIYMLKTNFSIGRIRATMLRRVVDP----------KEDKKGLVNGimPDPVAIPSHHGPDVKTVLPD--VDIVTTAF 214 Archaeoglobus ...
2YYY_A        149 LCRILYAINSIADIKKARIVLVRRAADP----------NDDKTGPVNAitPNPVTVPSHHGPDVVSVVPEFEGKILTSAV 218 Methanocaldoco...
O27090        145 LCRTLKPIDDLCGIKKVRAVMVRRGADP----------VQVKKGPINAivPNPPTVPSHHGPDLKTVMK--GVNIHTVAL 212 Methanothermob...
jgi:Mfer_0276 145 LCRTLKPLHDSFGIKKVRAVIVRRGADP----------AQVSKGPINAiiPNPPKLPSHHGPDVKTVLD---INIDTMAV 211 Methanothermus...
P0C6C2        164 IVPIIKVLDDAFGIDSGTITTIHSSMNDQQVIDaYHn--DLRRTRAAS--QSIIPVDTKLHKGIERIFPKFSNKFEAISV 239 Vibrio cholera...
2XF8_F        159 IIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDaYH--PDLRRTRAAS--QSIIPVDTKLAAGITRFFPQFNDRFEAIAV 234 Escherichia co...
P55971        156 IAPICAILDKAFKIKEGMLTTIHSYTSDQKLIDlAHp-LDKRRSRAAA--SNIIPTTTKAALALHKVLPNLKNKMHGHSV 232 Helicobacter p...
O25902        154 SAPLLKILDEAFKVENALLTTIHSYTNDQNLLDtKH--KDIRRARAAG--LNLIPTSTGVSKAISLVLPHLGPKVTGLAI 229 Helicobacter p...
XP_001704035  193 LAPLAKVIHENFGIKQALMSTIHAVTATQPVTDsVMkkRDWRSGRACL--SNIIPASTGAASALTLVIPELAGRITGTSW 270 Giardia lambli...
3HJA_A        255 RVPVPTGSIVDLTVQLKKKdVTKEEINSVLRKASEt---PELKGILGYTEDPIVSSDIKGNSH--SSIVDGLETMVLEng 329 Borreliella bu...
O28542        215 KLPTTLMHVHSLCVEMREA-VKAEDVVSALSEEPRimliSAEDGFTSTAKVIEFARELRLRYDl-YENIVWRESIGVDgn 292 Archaeoglobus ...
2YYY_A        219 IVPTTLMHMHTLMVEVDGD-VSRDDILEAIKKTPRiitvRAEDGFSSTAKIIEYGRDLGRLRYdiNELVVWEESINVLen 297 Methanocaldoco...
O27090        213 LVPTTLMHQHNIMVELEDP-VEADEIKARLDETTRvmlvRASEGLASTAEIMEYAKELGRSRNdlFEIPVWEESINVVdg 291 Methanothermob...
jgi:Mfer_0276 212 IVPTTLMHQHNVMVEVEET-PTVDDIIDVFEDTPRviliSAEDGLTSTAEIMEYAKELGRSRNdlFEIPVWRESITVVdn 290 Methanothermus...
P0C6C2        240 RVPTVNVTAMDLSVTIKSN-VKVNDVNQTIVNASQ----CTLRGIVDYTEAPLVSIDFNHDPH--SAIVDGTQTRVSNgq 312 Vibrio cholera...
2XF8_F        235 RVPTINVTAIDLSVTVKKP-VKANEVNLLLQKAAQ----GAFHGIVDYTELPLVSVDFNHDPH--SAIVDGTQTRVSGah 307 Escherichia co...
P55971        233 RVPSLDVSMIDLSLFLEKK-APKDPINDLLIEASK----GVLKGVLEIDLKERVSSDFISNPH--SVIIAPDLTFTLen- 304 Helicobacter p...
O25902        230 RVPTPNVSLVDLSLNFKKS-VSKASVQHALKDACK----HAFKGVVSIDEERLVSSDFISSPF--SAIVIDDQIMTIGek 302 Helicobacter p...
XP_001704035  271 RVPVQDVSVVDLVVETEKD-TSYAEICAAVKRACEt--pDELCGIMAYRDDFCVSSDFLTTTT--ISNFDSKSGIELHsr 345 Giardia lambli...
3HJA_A        330 faKILSWY 337 Borreliella burgdorferi B31
O28542        293 dlFVTQAV 300 Archaeoglobus fulgidus DSM 4304
2YYY_A        298 eiFLMQAV 305 Methanocaldococcus jannaschii DSM 2661
O27090        292 elFYMQAV 299 Methanothermobacter thermautotrophicus str. Delta H
jgi:Mfer_0276 291 eiYYMQAV 298 Methanothermus fervidus DSM 2088
P0C6C2        313 lvKMLVWC 320 Vibrio cholerae O1 biovar El Tor str. N16961
2XF8_F        308 liKTLVWC 315 Escherichia coli K-12
P55971        305 mvKIMGWY 312 Helicobacter pylori 26695
O25902        303 naKVLAWY 310 Helicobacter pylori
XP_001704035  346 ffKLVSWY 353 Giardia lamblia ATCC 50803
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap