3NZQ,1KO0,5X7M,4ZGZ


Conserved Protein Domain Family
Orn_Arg_deC_N

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pfam02784: Orn_Arg_deC_N 
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Pyridoxal-dependent decarboxylase, pyridoxal binding domain
These pyridoxal-dependent decarboxylases acting on ornithine, lysine, arginine and related substrates This domain has a TIM barrel fold.
Statistics
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PSSM-Id: 397077
Aligned: 15 rows
Threshold Bit Score: 248.35
Threshold Setting Gi: 305677838
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3NZQ_A 100 LRSINAAFKRARESYGyn-gDYFLVYPIKVNQHRRVIESLIHSGepLGLEAGSKAELMAVLAHAGM----TRSVIVCNGY 174 Escherichia coli K-12
P23630  38 VALIRERAKSFKQAFIsaglKAQVAYASKAFSSVAMIQLAEEEG--LSLDVVSGGELYTAVAAGFP----AERIHFHGNN 111 Bacillus subtilis sub...
P44316  34 RATLERHWHAFDSAFGn--rPHLICFAVKSCSNIGVLNIMAKLG--SGFDIVSQGELERVLAAGGD----ASKVVFSGVA 105 Haemophilus influenza...
1KO0_A  32 dAQIIRRQIAALKQFD------VVRFAQKACSNIHILRLMREQG--VKVDSVSLGEIERALAAGYNpqthPDDIVFTADV 103 Escherichia coli
5X7M_B  50 EDDFRSRCRDMATAFGg---PGNVHYASKAFLTKTIARWVDEEG--LALDIASINELGIALAAGFP----ASRITAHGNN 120 Corynebacterium gluta...
P41931  47 LDKIIERFQLWKRELP----MIEPFYAVKCNTDLVLIRILASLG--CGFDCASKDEIDIVMGTGVS----AERIIYANPC 116 Caenorhabditis elegans
P40808  38 LSSLERKLRLWHKLMP----RIEPHYAVKCNDDPVVVKFLADLG--TGFDCASKNELKLVLGLGVS----PERIIFAHPC 107 fruit fly
P40807  38 LSSVERKLRLWQKLLP----RIKPFYAVKCNDDPMVVRLLAQLG--AGFDCASKNEVKLVLGFDVS----PERIIFANPC 107 fruit fly
Q382G4  65 LGDIVRKHETWKKCLP----RVTPFYAVKCNDDWRVLGTLAALG--TGFDCASNTEIQRVRGIGVP----PEKIIYANPC 134 Trypanosoma brucei
P27117  45 LGDILKKHLRWLKALP----RVTPFYAVKCNDSRTIVKTLAAIG--TGFDCASKTEIQLVQSLGVP----PERIIYANPC 114 cattle
3NZQ_A 175 KDREYIRLALIGEKMghkvYLVIEKMSEIAIVLDEAERlnvvPRLGVRARL-ASQGSGKWqssggeKSKFGlAATqvlQL 253 Escherichia coli K-12
P23630 112 KSREELRMALEHRIG----CIVVDNFYEIALLEDLCKEtghsIDVLLRITPgVEAHTHDYittgqeDSKFG-FDLhngQT 186 Bacillus subtilis sub...
P44316 106 KSREEIMRALEVRIR----CFNVESVSELKHINQIAGEmgkiAPISLRVNPdVDAHTHPYistglkENKFG-VSVn--EA 178 Haemophilus influenza...
1KO0_A 104 IDQATLERVSELQIP-----VNAGSVDMLDQLGQVSPG----HRVWLRVNPgFGHGHSQKtntggeNSKHG-IWY---TD 170 Escherichia coli
5X7M_B 121 KGVEFLRALVQNGVG----HVVLDSAQELELLDYVAAGegkiQDVLIRVKPgIEAHTHEFiatsheDQKFG-FSLasgSA 195 Corynebacterium gluta...
P41931 117 KTRSFIAHAMDRDVK----MMTFDNPEELLKIAKLHPN----AEMILRIAVsDPTATCPL------NLKFG-ADPi--IA 179 Caenorhabditis elegans
P40808 108 RPASHLRYAKEQQVV----NGTVDNEYEIYKLRKHYPD----SNLIVRFKSeAKKALCPL------GDKYG-CDAe--AD 170 fruit fly
P40807 108 RPVSHLEYAKEHQVS----NGTVDNEFEVYKLHTHYPN----SNLIVRFKSeAKEAQCPL------GDKFG-CDAd--VD 170 fruit fly
Q382G4 135 KQNSHIRYARDSGVD----VMTFDCVDELEKVAKTHPK----AKMVLRISTdDSLARCRL------SVKFG-AKV---ED 196 Trypanosoma brucei
P27117 115 KQVSQIKYAANNGVQ----MMTFDSEVELMKVARAHPK----AKLVLRIATdDSKAVCRL------SVKFG-ATL---KT 176 cattle
3NZQ_A 254 VETLREAGRLDSLQL--LHFHLGSQMANIRDIATGVRESARFYVELH-KLGVNIQCFDVGGGLg-vDYEGtrsqsdcsvn 329 Escherichia coli K-12
P23630 187 ERAIEQVLQSEHIQLlgVHCHIGSQIFDTAGFVLAAEKIFKKLDEWRdSYSFVSKVLNLGGGFg-iRYTEdde------p 259 Bacillus subtilis sub...
P44316 179 REVYKLASTLPNIKItgMDCHIGSQLTELQPFLDATDRLIVLMEQLK-EDGITLKHLDLGGGLg-vTYTDetp------- 249 Haemophilus influenza...
1KO0_A 171 LPAALDVIQRHHLQLvgIHMHIGSGVD-----YAHLEQVCGAMVRQViEFGQDLQAISAGGGLs-vPYQQgee------a 238 Escherichia coli
5X7M_B 196 FEAAKAANNAENLNLvgLHCHVGSQVFDAEGFKLAAERVLGLYSQIHsELGVALPELDLGGGYg-iAYTAaee------p 268 Corynebacterium gluta...
P41931 180 APQLLKTASEEGINVvgISFHVGSGCNDASAYRNALQHAKNLCEIGE-GLGFKMDIIDMGGGFpgaEHHNp--------- 249 Caenorhabditis elegans
P40808 171 AAALMLLAKALGLKVtgTSFHVGSGCSEVEAYDRAIEKAENIFKVGE-MIGHKMELLDVGGGFpgiDDEm---------- 239 fruit fly
P40807 171 AAALMLLAKSLELKVtgTSFHVGSGCSELQAYDRAIKKAKNLFKFGA-LLGYDMDFLDIGGGFpgsDDVk---------- 239 fruit fly
Q382G4 197 CRFILEQAKKLNIDVtgVSFHVGSGSTDASTFAQAISDSRFVFDMGT-ELGFNMHILDIGGGFpgtRDApl--------- 266 Trypanosoma brucei
P27117 177 SRLLLERAKELDIDVigVSFHVGSGCTDPETFVQAISDARCVFDMGA-EVGFNMYLLDIGGGFpgsEDVkl--------- 246 cattle
3NZQ_A 330 ygLNEYANNIIWAIGDACEenGLPHPTVITESGRAVTA 367 Escherichia coli K-12
P23630 260 lhATEYVEKIIEAVKENASryGFDIPEIWIEPGRSLVG 297 Bacillus subtilis subsp. subtilis str. 168
P44316 250 phpSDYANALLEKLKNY------PELEIILEPGRAISA 281 Haemophilus influenzae Rd KW20
1KO0_A 239 vdTEHYYGLWNAAREQIARhlGHP-VKLEIEPGRFLVA 275 Escherichia coli
5X7M_B 269 lnVAEVASDLLTAVGKMAAelGIDAPTVLVEPGRAIAG 306 Corynebacterium glutamicum ATCC 13032
P41931 250 --FEKIAETIRDALDEFFP---DTNKRLIAEPGRFFAA 282 Caenorhabditis elegans
P40808 240 --FEEIAQSVNTSVELRFP---DKRIRIISEPGRFFVE 272 fruit fly
P40807 240 --FEKIAESVNTSVQRHFP---DERVHIIAEPGRFFVA 272 fruit fly
Q382G4 267 -kFEEIAGVINNALEKHFP--PDLKLTIVAEPGRYYVA 301 Trypanosoma brucei
P27117 247 -kFEEITSVINPALDKYFP--SDSGVRIIAEPGRYYVA 281 cattle
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