2Q27,4K9Q


Conserved Protein Domain Family
TPP_enzyme_N

?
pfam02776: TPP_enzyme_N 
Click on image for an interactive view with Cn3D
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
Statistics
?
PSSM-Id: 397069
Aligned: 80 rows
Threshold Bit Score: 86.1389
Threshold Setting Gi: 121683238
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2Q27_B         10 GMHIIVEALKQ-NNIDTIYGVVGIPVTDMARHAQAEg--IRYIGFRHEQSAGYAAA--ASGF--LT-QKPGICLTVS-AP 80   Escherichia coli
XP_001616208  625 LFDVLALCLKKaHLDDYLYGVYGIPLNKVLPSFVGNq--VHYISFRNEINACLSGSyvNYFDqqRGkKKVGMILTCS-GP 701  malaria paras...
Q17475         74 GASITAAALKS-QGVEYMFGVVGFPVIEVGMAAQAHg--IKYIGCRNEQAAAYAAQ--AMGY--LT-GKPVALLVVS-GP 144  Caenorhabditi...
Q54DA9          3 GVEIIAKSIKN-SAIEKVFGIVGVPITPIAYELQAQg--VGFFGFRNEQSCSYAASivGY----LT-GLPGLCMTVS-GP 73   Dictyostelium...
EAW15205        6 GAQLIARTLRD-LGVTVIFGIVGIPVVEIAEEAIDLg--IRFVAFRNEQACSYAAS--VYGY--MT-GRPGVCLVVG-GP 76   Aspergillus c...
Q0W895          3 VEQAVIDVMKQ-CGIDTVLTLPCDRMKNFLPLIPKN---FREIPLSREEGGVGIAA--GLYM--SG-KKPAMVIQST--- 70   uncultured me...
Q63MP1          4 kteDLIGILTD-AGVDLAVGVPDSLLKSFCGRLNDPdcpLRHLVASSEGGAVGIAI--GHHL--AT-GGLAAVYMQNsGI 77   Burkholderia ...
WP_015871973    3 sSTVIIDVLKK-EDVCFYSGVPDSLLKEFCMELDKPdngINHIIAANEGCAVGMAI--GNYL--VT-GKIPVVYLQNsGI 76   Edwardsiella ...
EAQ41852        7 LAQLVIAACHQ-FNVDTVVISPGSRNAPLTIGFSNHp-eIETLSVVDERCAAFFAL--GIAQ--QT-QKPVAVLCTS-GS 78   Polaribacter ...
Q8Y6K9         11 ylAAFIEELVQ-AGVKEAIISPGSRSTPLALMMAEHp-iLKIYVDVDERSAGFFAL--GLAK--AS-KRPVVLLCTS-GT 82   Listeria mono...
2Q27_B         81 -GFLNGLTALANATVN-GFPMIMISGSSDRAIVDl-------qQGDYE-EL-----DQMNAAK-PYAKAAFRVNQPQDLG 144  Escherichia coli
XP_001616208  702 -AFVNALPGLYNAKVN-HFPLIFICFENFTAKNLtpfdkhqnfQYFPQqQFl---aKAKEM---CAG--VFHVDSPDAFP 771  malaria paras...
Q17475        145 -GILHAIGGLANATVN-CWPVVCIGGTADVDLEN---------RGAFQ-EW-----SQQESVR-NSCKHVSRPTSLHTIP 206  Caenorhabditi...
Q54DA9         74 -GVVHALAGVLNAQSN-GWPMILLSSSIDQSLVG---------KGGFQ-EC-----KQFESAE-LYCKKCYYLTEIDHFP 135  Dictyostelium...
EAW15205       77 -GVLHAMAGIGNSAAN-NFPLLVLAGSAETSGVS---------KGAFQ-EM-----DAISFLT-PHTKFAVRPPSLDYVA 138  Aspergillus c...
Q0W895         71 -GIGNSLTALSSLHKTyDLPLPILASWRGVYKESiqaq--vhfGKFLPgVL-----DNMGI--------PYLVAEKPADL 134  uncultured me...
Q63MP1         78 gNAINPLVSLADRAVY-GIPLVLIVGWRAEISVSgaqv-hdepQHVTQgRItlpllDALSI-R-HLV-LERAGGENDALA 152  Burkholderia ...
WP_015871973   77 gNITNPVCSLSAEEVF-RIPLLFIIGWRGEIDQNgiql-adepQHRMQgETt---lSLLESLRiPYS--ILTPEMEDENA 149  Edwardsiella ...
EAQ41852       79 -ALLNYYPAIAEAFYS-NIPLVVISADRPKHLIDigdgqtirqENVFEnHIl---fSANLI---------ENPKFKTRNA 144  Polaribacter ...
Q8Y6K9         83 -AAANYFPAVAEANLS-QIPLIVLTADRPHELRN---------VGAPQ-AM-----DQLHLYG-SHVKDFTDMALPENSE 144  Listeria mono...
2Q27_B        145 IALA-------RAIRVSVSGRPGGVYLDLPANVLAATMEKD 178  Escherichia coli
XP_001616208  772 EQFF-------TCLETC-IRMKSPVYLNLSYHLIGEEVTLD 804  malaria parasite P. vivax
Q17475        207 AHIE-------KAVRCAMYGRPGAVYVDLPGNLVLTSTEEE 240  Caenorhabditis elegans
Q54DA9        136 EILK-------DAIETSLSNRPGPVYIQIPADLIKSKCKES 169  Dictyostelium discoideum
EAW15205      139 GAVQ-------NAYRTCWYGRPGPTFVDLPADLIQGKSTPG 172  Aspergillus clavatus NRRL 1
Q0W895        135 PAVR-------KAIDQS-YKENTPYVILFSPKIWEGSTAKE 167  uncultured methanogenic archaeon
Q63MP1        153 PSIA-------QLIASA-RQTSQPVALVVRKDAFDDASASq 185  Burkholderia pseudomallei
WP_015871973  150 EEII-------SELITLLRHSLTPVALVVRKNTFKKlknnk 183  Edwardsiella ictaluri
EAQ41852      145 QLIG-------EALQLA-NSNKGPVHINVPFDEPLYDTVSD 177  Polaribacter sp. MED152
Q8Y6K9        145 EMLRyakwhgsRAVDIAMKTPRGPVHLNFPLREPLVPILep 185  Listeria monocytogenes EGD-e
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap