5B47,2V3W,3EYA,1POW,4QPZ


Conserved Protein Domain Family
TPP_enzyme_C

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pfam02775: TPP_enzyme_C 
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Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
Statistics
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PSSM-Id: 397068
Aligned: 323 rows
Threshold Bit Score: 45.2687
Threshold Setting Gi: 81504691
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5B47_B  43 GIGCSGK----IPHFMNlpisgVHTLHGRSIAFATGIKLsnpsL----EVIVNVGDGDGLGIgMGHFVHLGRRNIDIAVL 114 Sulfurisphaera tokoda...
Q8R837 361 DIGCYTLgaapPLEAID-----TCICMGASISGSHGFQKaiehSgrkqKIFSVIGDSTFFHSgITGLIDIVYNKGNAVPI 435 Caldanaerobacter subt...
Q6LZB6 360 DIGCYTLggfePLNAID-----TTICMGASIGMAHGFEMargk-efakKSVAVIGDSTFWHSgVTGLIDIVYNKGHSTVI 433 Methanococcus maripal...
Q97HL0 361 DIGCYSLgallPLRSID-----SCICMGASIGIAHGMEKargt-efinRTVAILGDSTFIHSgITGLIDIVYNKGNSTVI 434 Clostridium acetobuty...
Q6ANT1 392 DIGCYTLgflpPLSAMD-----ACVCMGASVPMAHGMAKalge-gshdKVVSVIGDSTFIHSgITGLINTVYNNSASTLI 465 Desulfotalea psychrop...
Q74CD5 360 DIGCYTLgfmpPLNAMD-----TCVCMGASISSASGIVRvlsd-eekkKVVAVIGDSTFLHTgVNSLMEMAYNKAPATVV 433 Geobacter sulfurreducens
Q97B81 382 DIGCYTLgalpPFNEQD-----SATNMGSSVGISNGVFRat-----gqIPVSIIGDSTFFHSgLQGVANAVYNGTPEIII 451 Thermoplasma volcanium
Q97WQ2 388 DIGCYTLgllpPFDAQD-----SSTDMGSSIGIANGVYRat-----gnIPIAVIGDSTFFHSgISALANAVYNQTPMLVL 457 Saccharolobus solfata...
Q974C0 376 DIGCYSLgilpPFQEQD-----SLTNMGSSLGIANGVFRat-----giIPVAIIGDSTFFHSgLSALANAVYNNLPVLVV 445 Sulfurisphaera tokodaii
Q703W1 425 DIGCYSLgv--nLGEQD-----VLTHMGSSLGLGMGIAQadr----ekLVVATIGDSTFYHAaLPQLVDLKTKRVPLLLV 493 Thermoproteus tenax
5B47_B 115 VHNNGVYGLTKGQaspTLHRGEKTKSLPKpniMDAVNPLAVALAAGYTfVArgY--AYdvMHLKELIKKAI----LHKGS 188 Sulfurisphaera tokoda...
Q8R837 436 ILDNRITAMTGHQ---HNPGTGKTLMGED---APEIDIAKLSEAIGVKrVR--VvnPFklKEIEDAVDEAM----NTDDT 503 Caldanaerobacter subt...
Q6LZB6 434 ILDNSITAMTGHQ---ENPSTGKTLSGER---TNQIDFEALGRSIGINrIC--VvdAYdlKALEETIKEEV----NAEEP 501 Methanococcus maripal...
Q97HL0 435 ILDNAVTAMTGYQ---SNPTTGYNIKNEA---TKKVELEKLCRAVGVErIK--VvdPFnvDEVESVVKEEI----AACEP 502 Clostridium acetobuty...
Q6ANT1 466 ILDNRITAMTGQQ---QNPATGYNIKGEA---ANALDLEALCRAVGVKhVY--TvdPHdiIKTREVMKEAV----ALDEP 533 Desulfotalea psychrop...
Q74CD5 434 ILDNRITAMTGRQ---DNPASGWTLMDDS---TNAVDLVQLCTALGIRhVR--VvdPLdlDQTRAALQEEM----NRPEP 501 Geobacter sulfurreducens
Q97B81 452 VLDNRSTAMTGQQ---PSPST-------------HISIENVARAMGIDfVD--TfdPFdvKEGSDAVQKAAeyvkENKKP 513 Thermoplasma volcanium
Q97WQ2 458 VLDNRSTAMTGQQ---PSPSK-------------EIDIGEVAKGLGVKyVR--YvdPFdvNSSIRELSNALkwvkDNKQP 519 Saccharolobus solfata...
Q974C0 446 VLDNRVTAMTGQN---PSPSK-------------EIDIANVAKGLGVEyVR--EidPFnlKESTKIIADATnwvkQNRKP 507 Sulfurisphaera tokodaii
Q703W1 494 VMDNEYTAMTGGQ---PSPSR-------------DAPAEIFAQALGIKyF---VvdPAdvKTSVEKIREAVsl-aKSGEP 553 Thermoproteus tenax
5B47_B 189 ALVDI 193 Sulfurisphaera tokodaii str. 7
Q8R837 504 MVIIA 508 Caldanaerobacter subterraneus subsp. tengcongensis
Q6LZB6 502 SLIIT 506 Methanococcus maripaludis
Q97HL0 503 SVIIA 507 Clostridium acetobutylicum
Q6ANT1 534 SVVIS 538 Desulfotalea psychrophila
Q74CD5 502 SVIIT 506 Geobacter sulfurreducens
Q97B81 514 ALIVA 518 Thermoplasma volcanium
Q97WQ2 520 AVVIA 524 Saccharolobus solfataricus
Q974C0 508 ALIVA 512 Sulfurisphaera tokodaii
Q703W1 554 AVVVS 558 Thermoproteus tenax
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