5ODC


Conserved Protein Domain Family
CCG

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pfam02754: CCG 
Cysteine-rich domain
The key element of this family is the CX31-38CCX33-34CXXC sequence motif normally found at the C-terminus in archaeal and bacterial Hdr-like proteins. There may be one or two copies, and the motif is probably an iron-sulfur binding cluster. In some instances one of the cysteines is replaced by an aspartate, and aspartate can in principle also function as a ligand of an iron-sulfur cluster. The family includes a subunit from heterodisulphide reductase and a subunit from glycolate oxidase and glycerol-3-phosphate dehydrogenase.
Statistics
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PSSM-Id: 397052
Aligned: 59 rows
Threshold Bit Score: 63.4863
Threshold Setting Gi: 81669095
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5ODC_B   3 YAFFLGCimp---nrYAGVEAATRTVMEKLGVELVDM-TGASCCPAPGVFGSFDQ---KTWlTLAARNLCIAEEMGVD-I 74 
O25377 322 ITYHNPCh-------AKKTLNAHKEVRNLLNLHYEIKeMPDNCCGFGGITMQTQKa-gFSL-KVGLLRAKEIIDTKAAiL 392 Helicobacter pylori
P43801 322 VAYHTAChvdk-agwAPYTLEVLKKIPSLEIIMLP-----SQCCGIAGTYGFKSEnyeISQ-SIGKNLFDNINEGGFDyV 394 Haemophilus influenza...
P0A996 293 VVYHTPChmek-mgwTLYTLELLRNIPGLELTVLD-----SQCCGIAGTYGFKKEnypTSQ-AIGAPLFRQIEESGADlV 365 Escherichia coli K-12
P52074 302 LAFHCPCtlqhaqklNGEVEKVLLRL-GFTLTDVPDS---HLCCGSAGTYALTHPd--LAR-QLRDNKMNALESGKPEmI 374 Escherichia coli K-12
O24951 132 ITWHSNChalrvakvIDSAKNLIRQLKNVELIELEKE---EECCGFGGTFSVKEPe--ISA-VMVKEKIKNIESRQVDvI 205 Helicobacter pylori
Q9RT58 134 VTYHPTChamrslrvGDAPLKLLQNVRGMTLVELEGA---NECCGFGGTFAVKNPd--VSA-AMLTDKARHIMDTGAEaC 207 Deinococcus radiodurans
Q9XAB0 138 VTYHPTChglrslglGDRPRRLLEAVKGLELVELPGA---EECCGFGGTFAVKNSd--VSA-AMGTDKVRNAESTGADvL 211 Streptomyces coelicolor
P77252 132 AVYHPSCslarklgvKDEPLTLLKNVRGLELLTFAEQ---DTCCGFGGTFSVKMAe--ISG-EMVKEKVAHLMEVRPEyL 205 Escherichia coli K-12
O07020 131 ATLHTSChmtrllgvRKEPMKLLSHVKGLQFTELPGK---HNCCGFGGTFSVKMAq--ISE-QMVDEKVECVEETGAEvL 204 Bacillus subtilis sub...
5ODC_B  75 VTVCNGCYGSL 85 
O25377 393 SAECGACHMQL 403 Helicobacter pylori
P43801 395 ISECQTCKWQI 405 Haemophilus influenzae Rd KW20
P0A996 366 VTDCETCKWQI 376 Escherichia coli K-12
P52074 375 VTANIGCQTHL 385 Escherichia coli K-12
O24951 206 VSADAGCLMNI 216 Helicobacter pylori
Q9RT58 208 TAGDNSCLLHI 218 Deinococcus radiodurans
Q9XAB0 212 CAADNSCLMHI 222 Streptomyces coelicolor
P77252 206 IGADVSCLLNI 216 Escherichia coli K-12
O07020 205 IGADCGCLMNI 215 Bacillus subtilis subsp. subtilis str. 168
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