1VR7,2III


Conserved Protein Domain Family
AdoMet_dc

?
pfam02675: AdoMet_dc 
Click on image for an interactive view with Cn3D
S-adenosylmethionine decarboxylase
This family contains several S-adenosylmethionine decarboxylase proteins from bacterial and archaebacterial species. S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the biosynthesis of spermidine and spermine, is first synthesized as a proenzyme, which is cleaved post translationally to form alpha and beta subunits. The alpha subunit contains a covalently bound pyruvoyl group derived from serine that is essential for activity.
Statistics
?
PSSM-Id: 396996
Aligned: 243 rows
Threshold Bit Score: 48.2845
Threshold Setting Gi: 502942716
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1VR7_A          28 DREVLDNVQLIEQEXKQAAYESGA-T-IVTSTFHRF----LPYGVSGVVVISESHLTIHTWPEYGYAAIDLFTCGEdVDP 101 Thermotoga ma...
EIM65031       178 SSDMIKDPDCIKKIVSRLCEKLGI-VdTENISSVHYdeteTAAGFSMTRSIQTSGISGYFAHATHTAYLDIFSCNT-YEP 255 Desulfobacter...
WP_013177692    18 KEAPLVDEAHALGVARELLEALGLgStPTLTLTHR-----ARDGLSVGVALPESHLTLHTFQPAQRLSLGIFSRQT-LAL 91  Truepera radi...
jgi:Acfer_1468  16 AEDVVFDKEKIRDILEEAADRFSL-KeLALYATEND----EGDDFCFVMLCTNGHLFLHVFPTYGYVEADIFTLESgANP 90  Acidaminococc...
WP_007069130    17 KKEILLSSAEILNTMSDSAVYLGL---NVEDTYFHD----GEEEITVSAYGPRSHICIHAYPDMGYVAIDIYSFDPeLIP 89  Dialister inv...
CDD81044        17 RPSSIDSSPDLLAAMIDAAEKIGM---TLKENFCHE----SEDEVIIAAYGDKSHICVHAYPQLCYAAVDIYSFDAdLKP 89  Dialister sp....
CDA50507        17 VQEEITSSKELISVMNQAAKNLGI---EVEDTFFHE----DEEEITLAAYGKKAHVCIHAYPQLGYAAVDIYSFDCdILP 89  Dialister sp....
WP_127007784    17 LEDVVNSPLIIQESVTNALEAAQQ---PIDEISCQV----LDDEVVLFAVSPHCHIAVHAYPDMGYVAVDIYTFDLpLQA 89  Veillonella s...
CCC74216        16 cKATFTEAEDLQPLVERAFDLVDT---PVEGITFFH----IDDELTCIAVSGNAHICIHAYPTLSYVAVDIYSFNIdLKT 88  Megasphaera e...
CDA67529        12 cSEIINDTEAIKRAAHRAIEYVGA-D-IVEECIHKF----EPIGVTYFAVISTSHFSVHTWPEYGYAAVDIFSCTD-EVV 84  Clostridium s...
1VR7_A         102 WKAFEHLKKALKAKRVHV 119 Thermotoga maritima
EIM65031       256 RELAEFALSYFGGSHYKM 273 Desulfobacter postgatei 2ac9
WP_013177692    92 GEVLELLRVRFGlgrles 109 Truepera radiovictrix
jgi:Acfer_1468  91 EQVAVFLRQEFGPDQSKL 108 Acidaminococcus fermentans DSM 20731
WP_007069130    90 AKTMKAIRALLKPERIRA 107 Dialister invisus
CDD81044        90 TRTMVMLRNYFHPEKIRA 107 Dialister sp. CAG:357
CDA50507        90 ARAMAVLRSALEPEKIRA 107 Dialister sp. CAG:486
WP_127007784    90 TLIMRVLKQSFGAERVKA 107 Veillonella seminalis
CCC74216        89 SQIMSALKVNLRSDRIKA 106 Megasphaera elsdenii DSM 20460
CDA67529        85 EGITEILKTLFGAEKIVM 102 Clostridium sp. CAG:510
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap