2RMR,2LD7,2F05


Conserved Protein Domain Family
PAH

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pfam02671: PAH 
Paired amphipathic helix repeat
This family contains the paired amphipathic helix repeat. The family contains the yeast SIN3 gene (also known as SDI1) that is a negative regulator of the yeast HO gene. This repeat may be distantly related to the helix-loop-helix motif, which mediate protein-protein interactions.
Statistics
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PSSM-Id: 396992
Aligned: 358 rows
Threshold Bit Score: 26.6006
Threshold Setting Gi: 0
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2RMR_A         24 QVYNDFLDIMKEFKSQ--SIDTPGVISRVSQLFKGHPDLIMGFN-TFL 68  
XP_007856602  451 EIYEEFLKLLSLYSKE--IIDVKTLLDRTGAFF--DGDLLEEFK-ELv 493  Moniliophthora roreri MCA 2997
XP_001874054  495 EVYEEFLKLLGLFSKD--IFDVNTLIERTRVFL-GDGELMSEFK-DLv 538  Laccaria bicolor S238N-H82
XP_006654860   40 NVYSDFLRCMIKFRRQk-nISIEKCKQMVLRILDGHPRVIEAFQ-LFL 85   malo sina
XP_015637763  117 edFHALLNVLAKYYKNeiK-TSEEVLEKVERIIGNYPEFLEEFK-IFV 162  Japanese rice
EMS50858      133 DDYAAFLQTMQDFCRDr-TMTPQEVYSNVERCMRNCPELLEEFIdNFL 179  Triticum urartu
XP_006654860  116 eDYHAVLDIMVNFNKIdtV-VTEDIIDEVKRIVGNHPKILEEFN-FFL 161  malo sina
XP_003037381  371 EMYEDFLKTLTLFSKD--IFGVKDLIDRAKVFL-GDGDLLAEFK-ELL 414  Schizophyllum commune H4-8
XP_001829269  540 EVYEEFLKLLSLFSKD--IIDAKTLIERAKVFL-GDENLMAEFK-Dli 583  Coprinopsis cinerea okayama7#130
XP_007410013  775 EVWHEFLRVLELYNQT--IIDFKTLVDRVSVYIGDNDELLDDFK-GFV 819  Melampsora larici-populina 98AG31
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