1MGP,3EGL,6DKE,3FYS,6CNG,6NR1


Conserved Protein Domain Family
DegV

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pfam02645: DegV 
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Uncharacterized protein, DegV family COG1307
The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular function of fatty-acid binding and may play a role in the cellular functions of fatty acid transport or metabolism.
Statistics
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PSSM-Id: 426899
Aligned: 37 rows
Threshold Bit Score: 191.664
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MGP_A  27 KVKILVDSTADVPFSWXEKYDIDSIPLYVVWEDgRSEPDER--EPeEIXNFYKRIREAGSVPKTSQPSVEDFKKRYLK-Y 103 Thermotoga maritima
Q9I599   2 RIGLVVDATCDLPPEFLAAHGIRVMPIGIRLGE-QRLIDRRdpDT-TLSFYRDHLPKVGSKDGSQPLSAAELQQWFLD-E 78  Pseudomonas aeruginosa
Q9RDL7   4 HVAIVTDSTAYLPARAMERHGITAVPLTVVLGD-RALEEGT--EI-STRSLAQALQKRRPV-TTSRPNPELFAETYRR-I 77  Streptomyces coelicol...
3EGL_C   5 PVRVIVDSSACLPTHVAEDLDITVINLHVXNNG-------------EERS-------------TSGLSSLELAASYARqL 58  Corynebacterium gluta...
Q9CEH0   2 TFQIMTDSTADLSPYYIKKHHLTVLGMTVTVGE-ETYETIGeaAL-DNSTLLAAI-KKGATVHTSQINSGQFLEVFKK-F 77  Lactococcus lactis su...
P70945   2 TVHLIADSATDLPRSYFEEKGIGFIPLRVSLGD-KEFEDAV--TI-HADQIFEAM-QNGETPKTSQASPQTIKNVFLQ-Y 75  Bacillus subtilis sub...
Q9RX15   6 SFAVVTDGGLDAYPTLLN--DVPVAPFSVAFGE-RSYPMN---EV-SRQWLYDELGRNPAHPTSSQPSPQQWLDAYAA-- 76  Deinococcus radiodura...
Q9RSY3   2 SIAIVTDSTSDLTPEHLAALGVTGVPLYVLFEG-QLYQDGV--QL-SARQLVEGVRAGKAIPSTSQPSPAEFAQAYAQ-- 75  Deinococcus radiodura...
Q9RT62   1 MIAVTTESTADILPLQLGYSGIHLLPVPLGHQG-QVYSER---EL-PPDQLVNLIRTTGEPARTLAIDDEVVARTFEAaL 75  Deinococcus radiodura...
Q9RY87  13 SLKVIVDATADLSEADLARSGVWQLASVVRVGG-QSYSST---EL-SPERLLALIEAQGAAPVIEPPSVDAYEQVFRQ-- 85  Deinococcus radiodurans
1MGP_A 104 KEEDYDVVLVLTLSSKLSGTYNSAVLASKEV-----DIP----------VYVVDTLLASGAIPLPARVAREXLENGATIE 168 Thermotoga maritima
Q9I599  79 LVTDFDYVVCLTVDSLRSPIFEHATQASFGLlqhyhERRhaagiagpftLRVLDSHSVFAGIACLAAEGTRLLAQGSHPN 158 Pseudomonas aeruginosa
Q9RDL7  78 AESGADGIVSLHLSAELSGTHDAAVVAAREA-----PVP----------VRVVDTGMIAMALGFCALAAAETAEAGGTVD 142 Streptomyces coelicol...
3EGL_C  59 ERGGDDGVLALHISXELSSTWSAAVTAAAVFd----DDS----------VRVVDTSSLGXAVGAAAXAAARXAXDGASLQ 124 Corynebacterium gluta...
Q9CEH0  78 ASADEE-LLYLAFSSGLSGTYQSALIAQDMVleefpSAK----------ITVVDTLAAASGEGFLVEETVKLRDSGKSLT 146 Lactococcus lactis su...
P70945  76 AETG-DPALYIAFSSGLSGTYQTAVMIANEVkeefpDFD----------LRVIDSKCASLGYGLAVRHAADLCINGNTIQ 144 Bacillus subtilis sub...
Q9RX15  77 VPSGTD-ILAVTISSGLSGSRNAAAQARDLA-----GRQ----------VTLHDSMTLSAAQAFQVHAANVAAQRGESME 140 Deinococcus radiodura...
Q9RSY3  76 ALEHADEVLSLHISGQLSGTVGSARLAAQEF-----GGR----------VTVVDTHTVTLGLGLQVLRAAELVRAGQSVP 140 Deinococcus radiodura...
Q9RT62  76 QGSKSGRLVHVASGSRFTPHFEVAARVAGQF-----GVR----------VQVIDGGTVSYALGVQALHAAHLADQGADFG 140 Deinococcus radiodura...
Q9RY87  86 ALAQSDEVLSLHLSSRLSVSFACGQEAARAF-----GSR----------VRVLDSPAGSYALGLQALRAARLAAGGHNAA 150 Deinococcus radiodurans
1MGP_A 169 EVLKKLDERXKNKdfKAIFYVSNFDYLVKGG-----------RVSKFQGFVGNLLKIRVCLHIEN--GELIPYRKVRGDK 235 Thermotoga maritima
Q9I599 159 ALRTRLEQLSQQT--CTYLVADDLGHLRRRGfqkgdrsgfvdRVKGAALGLGSLLDVKPVFSLAD--GEDKPVALSPSFE 234 Pseudomonas aeruginosa
Q9RDL7 143 EAVTAAEKRAAGT--SAYFYVDTLDYLRRGG-----------RIGAAQALFGSALAVKPLLQLEG--GRIEPLEKVRTAS 207 Streptomyces coelicol...
3EGL_C 125 ECYDIAVDTLXRS--ETWIYLHRIDEIWXSG-----------RISTATAXVSTALATRPIXRFNG--GRXEIAAXTRTQS 189 Corynebacterium gluta...
Q9CEH0 147 ETLEVLSDIIPRL--QSRFMVDDLNHLARGG-----------RIPKAVALVGTMANIKPLLDVDPe-GRLRQVTKVRGKK 212 Lactococcus lactis su...
P70945 145 EIETSVKNFCSQL--EHIFTVDDLTYLARGG-----------RISKTSAFVGGLLNIKPLLQMED--GKLVPLEKIRGQK 209 Bacillus subtilis sub...
Q9RX15 141 TAIAWMNAVQAET--ELQFTIETLEYLRRGG-----------RIGTVAAALGGLLNLKPVVMVDKktGTYVNAGRARSYR 207 Deinococcus radiodura...
Q9RSY3 141 QIVQTLERVYPQA--DLRFTVDTLDFLRLNG-----------RIGGASALLGGLLNIKPLLVVRG--GRVDAGGRVRGQK 205 Deinococcus radiodura...
Q9RT62 141 QIARALAELRERT--LLTFAVESLDFLRVNG-----------RIGNVAAFIGNWLGLRPLLAVEA--GEVVSKARVRGQA 205 Deinococcus radiodura...
Q9RY87 151 AIVSALRAVQARQ--LMHFTVSDVRFMHLSG-----------RITPVTAPLERSHDVQPIFRYHH--GLVELTARAPDHE 215 Deinococcus radiodurans
1MGP_A 236 KAIEALIEKL--REDTPEGSKLRVIGVHAD--NE-AGVVELLNTLRKSYEVV-DEIISPXGKVITTHVGPGTVGFGIEVL 309 Thermotoga maritima
Q9I599 235 KSAEKLFGYAlaRVQAGELLAPQLGLSYAGdpTAlRDLPGFAALENACRERDiHLHLGMLSPTGGINLGAGAMSLGFIAT 314 Pseudomonas aeruginosa
Q9RDL7 208 KAIARLEE-I--AADRAGGAPVDIAVHHLA--AP-DRASALADRLRDRVPGLaDLHVSEVGAVIGAHTGPGLLGVVVSSR 281 Streptomyces coelicol...
3EGL_C 190 XAFAXLVE-L--AQIRADGEPVFIAIGQNE--AR-EAAXQLEELLRNALPEGsSFXSVDIDPTLAVHSGPGAVSVSAVFA 263 Corynebacterium gluta...
Q9CEH0 213 KAINQLLEKSleEMDTAYP---RLLISYSG--TD-EIAQEIKKQAMQKKGIS-DVDVRPLSPTIVTHTGDGTIAIFSISR 285 Lactococcus lactis su...
P70945 210 KLFKRIIELM--KERGDDWSNQTVGISYAA--NK-EKATDMKHLIEEAFKPK-EIIMHPISSAIGSHAGPGTLAIFFLRK 283 Bacillus subtilis sub...
Q9RX15 208 GGIEAVTSQV--TRKYGEGTPLRVGLLYGT--HP-EDADQALEQLAARHPIV-WSDRTGVNPVLSVHVGPRALGVAAAPG 281 Deinococcus radiodura...
Q9RSY3 206 KALADLAEHV--RRYVSQHGGARVAFLATV--GGeEDRAAVRAQLSDLHFQ--DMGDHEIGAVVTVHAGPGAVGVALEPL 279 Deinococcus radiodura...
Q9RT62 206 AAVRTLLS-AthQFQHQTGETLRLYCGHTI--GGeGAAEQLQGQLQAVYRDL-PAPLHPLGSGLTANVGPGVVAVLAFPR 281 Deinococcus radiodura...
Q9RY87 216 AAMRQLARSVtkFVTETLPEGARVAFLHSP--GGeEGAERLRTLLSASGLTYeDAGTRSIGNHLLAVTGPRATGVVAEPL 293 Deinococcus radiodurans
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