Conserved Protein Domain Family
COX15-CtaA

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pfam02628: COX15-CtaA 
Cytochrome oxidase assembly protein
This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast.
Statistics
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PSSM-Id: 396960
Aligned: 62 rows
Threshold Bit Score: 132.795
Threshold Setting Gi: 81364603
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001267918 108 YWLLGSAASVFGIVVFGGLTRLTESGLSITE-WRPVTGS-LPPMNAEDWESEFAKYRASPEFQllnpnMNLSEFKSIYYM 185 Aspergillus cla...
WP_011830750  45 ALTVLTLFLTFDLVLFGAFTRLTDSGLGCPD-WPGCYGSaSPLGARDEIQAAQSVLPTGP------------VTHGKAWV 111 Methylibium pet...
Q8Y2G5        31 KLVWITAFLTLDLIMFGSFTRLTDSGLGCPD-WPGCYGTsNPFHARDDIHAAQAAMPSGP------------VTWMKAWI 97  Ralstonia solan...
Q2KTW9        10 KLVFFTWFLTLDLIMFGAFVRLTDSGLGCPD-WPGCYGKaSPLGALQDIHRAASDMPFGP------------VTLSKAWI 76  Bordetella aviu...
WP_011903767  36 KLNWVLVFMTFDLIVFGAFTRLTDSGLGCPD-WPGCYGTsNPFHALSDIAQAEHALPDGP------------VTVIKAWI 102 Polynucleobacte...
Q607I2        15 RIGIITIAAVYFLIMVGGIVRASGAGMGCPD-WPTCFGR-LVPPTDESQLPANYHEIYAERGY-----ADTRFNPVKTWT 87  Methylococcus c...
Q11SZ6        11 RIVFVSLVTIYLVILAGGIVRSTGSGMGCPD-WPKCFGT-YAPPLEESQLPADYKEKYAVQGH------PAVFNVYKTWT 82  Cytophaga hutch...
WP_012256898  10 nFAWLNVGYNLLVIMWGAFVRATGSGAGCGDhWPLCDGQ-VIPRSPD----------------------------TAQLI 60  Chloroflexus au...
Q5SLI3        11 gYAWGVLLWNVLVALFGAYVRATGSGAGCGAhWPTCNGE-VIPRAPQ----------------------------VETLI 61  Thermus thermop...
Q04443         7 IYSVITSIGVLIVLLQGALVTKTGSGEGCGAtWPLCFGE-VIPTNPA----------------------------IETII 57  Bacillus pseudo...
XP_001267918 186 EWIHRLWGRFIGLSFVFPALYFV-------AKKKV--SKPMALR-LAGIAGLIGFQGFIGWWMVKSGLKEdlfaqgsHPR 255 Aspergillus cla...
WP_011830750 112 EMVHRYLATAVGVLITVMTLLSWqqwrrdgRGSSEapTRVSPWW-ATVTLLWVCVQGAFGAFTVTLKL------------ 178 Methylibium pet...
Q8Y2G5        98 EMTHRYFALALGVLIITLVVLAWakrrelrQ---------SPWY-ATAVLGLVCLQGAFGAWTVTLKL------------ 155 Ralstonia solan...
Q2KTW9        77 EMIHRYVGGLLGLLIIAIVYMAWryrgrlgR---------SPAL-ATVALVAVCVQGAFGAWTVTHKL------------ 134 Bordetella aviu...
WP_011903767 103 EMIHRYLAMTVGTLILVQVGLAFskvktmgK---------APLIgSLGLLMLVCIQGAFGAWTVTLKL------------ 161 Polynucleobacte...
Q607I2        88 EYVNRLVGVSIGLLIIATLYRSLaf---wkTD------RTVTWL-ALTVFLAVGFQGWLGSAVVASNL------------ 145 Methylococcus c...
Q11SZ6        83 EYVNRLVGAIAGLIIVYQCIYATrf---lkTT------PKYFWY-SLLLAVLMASQGLLGAKLVSSYL------------ 140 Cytophaga hutch...
WP_012256898  61 EFSHRVTSGIALLLTIGLLVWAL-------RLFAA--GHPARRA-AIATMIFMIVESLIGAALVLFRLVAh-----dASL 125 Chloroflexus au...
Q5SLI3        62 EFTHRATSGLAFLSVLALFLWAL-------RAFPK--GHPARFG-AGLALFFMVTESLVGASLVLFGWTAd-----nVSR 126 Thermus thermop...
Q04443        58 EYSHRIVSGLVGAMIIILAIWAW-------KQLKH--MREAKAL-SFAAVILIIFQGLLGAGAVVFG------------- 114 Bacillus pseudo...
XP_001267918 256 VSQYRLTAHLAAAFVCYTAMLWNGLA--ILrshrlladpeagtkvldalRDPKLNIFRRSVAG-LALLTFVTVMSGGLVA 332 Aspergillus cla...
WP_011830750 179 -YPAIVTAHLLGGLALLALLAAQAWRpaa------------------drVVGVSSALRRSLVI-VSLLAVLQIALGAWVS 238 Methylibium pet...
Q8Y2G5       156 -QPAIVVTHLLLGMSLLAALIWLGCKndAPr-----------------lVDGRGASLRVPAAI-GLALLVAQIALGGWVS 216 Ralstonia solan...
Q2KTW9       135 -MPVVVTAHLVLGLSLLALMTWLAARerPHl-----------------pVPAAALRWRPWMAL-GLVLLAAQVTLGGWVS 195 Bordetella aviu...
WP_011903767 162 -QPIIVTIHLMLAITLLACLTAYAQQgwVDksa--------------tvRVIRIRPLPATLLLaGFVVLFSQIFLGAWVS 226 Polynucleobacte...
Q607I2       146 -RPVMITAHMLMAFAIVCLLIYAVTRsqRSrfa-------------tldLSSLPPRFCTVLMV-AMGMTLLQIAMGTQIR 210 Methylococcus c...
Q11SZ6       141 -KPILITLHMGVALLIMGILIWLLVEagKEkqrlh---------aadyaEEDLGRKYRWAMWV-FISLTVIQIFLGTEVR 209 Cytophaga hutch...
WP_012256898 126 TRALSLGLHLVNTFLLIGAMALTAWYasGKpa----------------pDLRGKGGLLSMLIA-ALVGTALVGSSGAITA 188 Chloroflexus au...
Q5SLI3       127 ERAVVQMVHLANTYFLLAALALTAWWasGGgp----------------lRLRGQGAVGLALFL-GLLALLFLGMSGAVTA 189 Thermus thermop...
Q04443       115 QSKAILALHFGISAMSLAAVVLLTILafEDgre-------------htmAPKVSRGFKYYVFF-VITYCYAVIYSGAYVK 180 Bacillus pseudo...
XP_001267918 333 GLDAGLIYNEFPFMGNGLTPPKAELFdprysrhedrsDLWWRNMLENPSLV-----------------QLDHRIMAMTTF 395 Aspergillus cla...
WP_011830750 239 TNYAVLAC-----------SD-FPTCqgr-----wwpTMDFEHGFAVLRPLgvgkdgawlpfaaltaiHMTHRLGALLLL 301 Methylibium pet...
Q8Y2G5       217 TNYAVLAC-----------TD-FPLCngq-----wvpPMDFAHGFTFWRELgrtaggdfishdalvaiHWTHRVFAAVVL 279 Ralstonia solan...
Q2KTW9       196 TNYAALAC-----------LD-FPTChgs-----lvpDMDFHGGFSLIRALgelpsgqmisqsaltaiHWVHRNFAFIVF 258 Bordetella aviu...
WP_011903767 227 TNYAVLAC-----------PD-FPTCiga-----lwpDTNWSEGFTLWRQLglnaqgdfispaalqtiHWAHRLFAVLVL 289 Polynucleobacte...
Q607I2       211 ESVDVMAA-TAATDRSLWREN-FPLI------------------------------------------FYVHRSFSAVIL 246 Methylococcus c...
Q11SZ6       210 ETIDIISYALDYQYKETWIAS-AGSI------------------------------------------FIIHRSYSILLT 246 Cytophaga hutch...
WP_012256898 189 LGDTLLQLGVLPGGV----------------------SQSITRDSHPLVWM-----------------RIIHPVLGTLVG 229 Chloroflexus au...
Q5SLI3       190 LGDLLFPV-----------GSTLEAL-----------ERSLTPGEHFLVRL-----------------RVLHPLIAVSVG 230 Thermus thermop...
Q04443       181 HSEATLAC-----------AG-FPLC-----------NGQIFPGLYGPVGA-----------------HYFHRVVGTILL 220 Bacillus pseudo...
XP_001267918 396 TSIMAL---WAYTrrsptmkrllPPAAKKGVHGvVAFACVQVSLGISTLLYLVPLPLASAHQAGSLCLLTW 463 Aspergillus clavatus NRRL 1
WP_011830750 302 GGLAWLvwrLARE----------PALRRYAAGL-VGVAAWQVVTGVSNVVLDWPLLAAVAHTGGAAALVLL 361 Methylibium petroleiphilum
Q8Y2G5       280 GYLAWLglrARRV----------AGIARVATVL-LTVLAVQLATGLSNIVLGWPLLAAVAHNGGAALLLLL 339 Ralstonia solanacearum
Q2KTW9       259 IYLGVLawrMRGI----------SGLSGPARLM-LVLLLAQLVTGLTTIFFQWPLLIAVLHNGGAAGLILA 318 Bordetella avium 197N
WP_011903767 290 IVLGTLglkGLKVtta-----atPDLGRISKLL-LGLLLLQLITGISNVVFQWPLLAALLHTAGSAALVFC 354 Polynucleobacter asymbio...
Q607I2       247 GVNLWLawkMVRSlp------adSLYARFGMVL-AGLVVAAIAAGVTLDRFGLPAIAQPLHLLLANLIFGT 310 Methylococcus capsulatus
Q11SZ6       247 AATIYFtfiLYKQra------lyPKAYRLSTKI-AAVIAIEIAAGITLAYFALPPWAQPIHLLFATVLLGV 310 Cytophaga hutchinsonii A...
WP_012256898 230 LAMISLaqrAVRYdp-------sPTTRRLAWAT-AAIFVGQIFLGAINVILKAPVWMQLVHLLFADLAWLA 292 Chloroflexus aurantiacus
Q5SLI3       231 LYVVFAgylVAHLrp-------sPLTRRLAQGL-AYLYGAQLLAGLINVALKAPVWMQILHLLLAYAIWLL 293 Thermus thermophilus HB8
Q04443       221 LFLLILmiwTLSRyr------hyRVLTWTAVLS-FLLVVGQFISGISIVFTQNALSVGLIHALIISILFSA 284 Bacillus pseudofirmus OF4
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