Conserved Protein Domain Family
DUF177

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pfam02620: DUF177 
Uncharacterized ACR, COG1399
This family is nearly universally conserved in bacteria and plants except the Chlorophyceae algae. Thus far, mutantional analysis in bacteria have not established a function. In contrast, mutants have embryo lethal phenotypes in maize and Arabidopsis. In maize, the mutant embryos arrest at an early transition stage.It has been suggested that family members specifically affect 23S rRNA accumulation in plastids as well as bacteria.
Statistics
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PSSM-Id: 396952
Aligned: 89 rows
Threshold Bit Score: 46.583
Threshold Setting Gi: 921993727
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6K976                             159 LDGIVRTVITLGCYGCAEPAPQGIFANFSLLLTEDRVEEPDVVDLgtifeeeqtkapsltgsqedgddedidwDDRLHFP 238 Japanese rice...
WGS:AAXU:1101174000282_ALPR1_13570  59 LDFHIKGIVTLTCDRSLEEYDQPLEFHESMLYKYGSEEKEIN-------------------------------EDVIMIT 107 Algoriphagus machipongonensis...
Q11UM0                              61 MNFILNGVVELVCDRSLDTFEQPISSENVLLFKYSEEEGEIT-------------------------------EEIIGIK 109 Cytophaga hutchinsonii ATCC 33406...
Q7MT51                              34 FCIALDGTVKTACDRCLDEVEILVKEENKLVVRFGDSYQELS-------------------------------DDLLVVP 82  Porphyromonas gingivalis...
WP_005679794                        58 LSFQTDGMVWVPCDRCLDDMELPISSSDKLMVKFGHEYAEEG-------------------------------ENLIVIP 106 Bacteroides caccae...
Q2S6I7                              56 VKMHATATAELTCDRTLQPYDEALEGQYNVLFGPPSMVGQEGDEF----------------------------EEVRPLD 107 Salinibacter ruber DSM 13855...
WP_012473650                        60 VDIETKTVAEFSCDRCLEPLKKELTGKYRILFAFSDTGALSEKSD----------------------------ENYRALD 111 Chlorobium phaeobacteroides...
Q8KAP5                              62 VTLNTSATANLTCDLCLAPITSELKGSYRIYYGYEQAGEPQEERD----------------------------EEYRLID 113 Chlorobaculum tepidum...
jgi:Paes_0180                       60 TAIETVTDAELSCDICLAPVHRRLSGQFTIFFVFGNQGNEAHETD----------------------------GEYRTLP 111 Prosthecochloris aestuarii DSM 271...
SNB35121                            70 LNFNHSGTINVPCDLTSEEFDLPINGNLKLIVRFGEIFNDEN-------------------------------EDLLILP 118 Flavobacterium psychrophilum...
Q6K976                             239 AGEKEIDISKHIRDIIHLEITLDALCS----P--TCKG--LCLGCGENLNTSSC----------------SCNAEKQ--- 291 Japanese rice...
WGS:AAXU:1101174000282_ALPR1_13570 108 RDTPSINVAQLIYEFILLNLPSKKIHPdyrnEldEEDYegEGSLVYIDDQDFED----------------EELDEDSves 171 Algoriphagus machipongonensis...
Q11UM0                             110 RETIKINIAQYIYEFINLEVPIKKLHP----RfqEEEVdnDTSETLLIYSTETE----------------NEEKSESpte 169 Cytophaga hutchinsonii ATCC 33406...
Q7MT51                              83 LSEGTLDLSSLLYEYSELAIPMQRMH-----SdgECDPemMNRMSDLLAIDAD-------------------EATEEsgm 138 Porphyromonas gingivalis...
WP_005679794                       107 EEEGEINVAWFMYEFIALSIPMKHVHA----Pg-KCNKamTSKLSKHLKTNANEdsdevfdtggddivieEEVEEQI--- 178 Bacteroides caccae...
Q2S6I7                             108 ASDREIDLTDMVRDTLLLAIPQRRIAPg--aEdePIERefGGTDDADEDDSAP------------------V-------- 159 Salinibacter ruber DSM 13855...
WP_012473650                       112 RNAVTVDLTEDVRETLLLSKPMKVVCA----DksACTLyqENSPLNADHESETA-----------------S-------- 162 Chlorobium phaeobacteroides...
Q8KAP5                             114 RNTLALDLTEDVRETLLLSVPMKVTCKd--nP--DCRVfhQEKLSEPGEDHL---------------------------- 161 Chlorobaculum tepidum...
jgi:Paes_0180                      112 PSATAIDLTEDVRETLLLSLPVKVVCEa--yP--ECNAlrTDEETQTEDDQT---------------------------- 159 Prosthecochloris aestuarii DSM 271...
SNB35121                           119 IGEHQVDVSQYIYEMVVLSIPLKKIHPg--iQdgTLETeaLSKLKEISVTEQAQd--------------eNVQEETEika 182 Flavobacterium psychrophilum...
Q6K976                             292 ---QAKnvqrR-GPLKDLL 306 Japanese rice
WGS:AAXU:1101174000282_ALPR1_13570 172 tdiDPR----W-ASLKNLK 185 Algoriphagus machipongonensis
Q11UM0                             170 dliDPR----W-LALKSLK 183 Cytophaga hutchinsonii ATCC 33406
Q7MT51                             139 tahDSR----W-DSLGKLL 152 Porphyromonas gingivalis
WP_005679794                       179 ---DPR----W-NELKKIl 189 Bacteroides caccae
Q2S6I7                             160 ---DPR----W-SALEELK 170 Salinibacter ruber DSM 13855
WP_012473650                       163 ----P-----WkESLEKLK 172 Chlorobium phaeobacteroides
Q8KAP5                             162 ----PDs--dWqESLEKLK 174 Chlorobaculum tepidum
jgi:Paes_0180                      160 ----QNs--nWkASLQELK 172 Prosthecochloris aestuarii DSM 271
SNB35121                           183 entDPR----W-DKLKTLL 196 Flavobacterium psychrophilum
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