4O2X


Conserved Protein Domain Family
ClpS

?
pfam02617: ClpS 
Click on image for an interactive view with Cn3D
ATP-dependent Clp protease adaptor protein ClpS
In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP. ClpS directly influences the ClpAP machine by binding to the N-terminal domain of the chaperone ClpA. The degradation of ClpAP substrates, both SsrA-tagged proteins and ClpA itself, is specifically inhibited by ClpS. ClpS modifies ClpA substrate specificity, potentially redirecting degradation by ClpAP toward aggregated proteins.
Statistics
?
PSSM-Id: 396950
Aligned: 259 rows
Threshold Bit Score: 51.2949
Threshold Setting Gi: 74688480
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
4O2X_A           405 ETSAWKVILYNDDIHNFTYVTDVIVKVVGqiSKAKAHTITVEAHSTGQALILSTWKSKAEKYCQELQQ------------ 472 Escherichia...
jgi:Cha6605_3097  15 LAPNYRVLLHNDDFNSMEHVVQVLMTNIPhmSETKAISVMMEAHQNEMALVIVCNQEHAEHYCDVLKS------------ 82  Chamaesipho...
BAI94209          39 LAPRYRVLLHNDDHNPMEYVVQVLMSTVPglTQPQAVSIMMEAHTNGLALVITCALEHAEFYCETLKN------------ 106 Arthrospira...
P74335            18 HAPRYRVLLHNDDFNSMEHVVQTLIQTVAgmTQPQAVDIMMEAHFNGMSLVITCELEHAEFYCETLRS------------ 85  Synechocyst...
Q31QE7            17 IAPRYRVLLHNDDFNPMEYVVMVLMQTVPslTQPQAVDIMMEAHTNGTGLVITCDIEPAEFYCEQLKS------------ 84  Synechococc...
WP_012954369      19 PVPRYKVLLHNDDFNPMDYVVQILMQTISgmTRPQAAEIMMEAHISGTALVITCAFEPAEFYRETLKN------------ 86  Candidatus ...
EES15037          78 MSPPYRVILHNDNYNRREYVVQVLMKVIPgmTVDNAVNIMQEAHVNGLSVVIVCSQSEAEEHCTSLRG------------ 145 sorghum
Q7NML9            15 PMPLYKVLLHNDDHTPMNYVIEVLMKTIPkmQPSKARKIMLEAHNGGVAVVIVCALEHAEFYSESLNR------------ 82  Gloeobacter...
Q2JHL4            15 HMPMYRVLLHNDDVNTMEYVVQVLVKVIPamMPPQATEIMLEAHHNGVAVVIVVPREHAEFYCEQLRQ------------ 82  Synechococc...
BAM02611          19 tlPPHVLVLHNDEQNTLGYVVDVLRRVLGl-SASRAWRLARVTHRRGRCAVWAGHRELAELKAVQVRAagpdpgvvalgd 97  Phycisphaer...
4O2X_A           473 --NGLTVS 478 Escherichia coli K-12
jgi:Cha6605_3097  83 --HGLTST 88  Chamaesiphon minutus PCC 6605
BAI94209         107 --HGLTST 112 Arthrospira platensis NIES-39
P74335            86 --HGLSST 91  Synechocystis sp. PCC 6803
Q31QE7            85 --HGLSSS 90  Synechococcus elongatus PCC 7942 = FACHB-805
WP_012954369      87 --HGLSSS 92  Candidatus Atelocyanobacterium thalassa
EES15037         146 --NGLRSS 151 sorghum
Q7NML9            83 --HNLTST 88  Gloeobacter violaceus PCC 7421
Q2JHL4            83 --HGLTSS 88  Synechococcus sp. JA-2-3B'a(2-13)
BAM02611          98 pcRPLRVS 105 Phycisphaera mikurensis NBRC 102666
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap