Conserved Protein Domain Family
SMC_ScpA

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pfam02616: SMC_ScpA 
Segregation and condensation protein ScpA
This is a family of proteins that from part of the condensin complex that regulates chromosome segregation. This is the A subunit, which binds to the ScpB subunit, pfam04079, and SMC, pfam02463, to participate in chromosomal partition during cell division. The condensin complex pulls DNA away from the mid-cell into both cell halves. These proteins are part of the Kleisin superfamily.
Statistics
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PSSM-Id: 280735
Aligned: 5 rows
Threshold Bit Score: 201.995
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P75478       178 LLIDKKFNLHQVDIAKITTQYLHLINTNlNKQAIEP-------ITDYLVITSRIVEQKANNLLqINDIAL--DSDFLDNK 248 Mycoplasma pneu...
P74212        16 MAHQGEINPWDVSVIDVIDRFLQDLGIL-NSLDLNFqqqnlprSGQAFLWASMLVRYKADSLHnLEQEPEevLPEAELEE 94  Synechocystis s...
O33208        40 LIFAHQLDVTEVALHQVTDDFIAYTKAIgARLELEE-------TTAFLVIAATLLDLKAARLLpAGQVDDeeDLA--LLE 110 Mycobacterium t...
WP_010908297  28 LICAHRLDVTEVALHQVTDDFIAYIRRLgPQLGLEE-------TTAFLVIAATLIDLKAARLLpAGRVEDeeDLA--LLE 98  Mycobacterium l...
P35154        21 LINRLEIDIYDIPVAKITEQYLLYVHTM-RVLELDI-------ASEYLVMAATLLSIKSRMLLpKQEEELfeDELLEEED 92  Bacillus subtil...
P75478       249 LRDKLVAQLVeykrYRESLDDFEKLRinrlAYfsKD-NDFNRFIQTVDKsntEPVKIEDelpnyvSvlklhHAMNKLMQR 327 Mycoplasma pneu...
P74212        95 WPDGLIARLP----RDLENRLRRRTAvp-pLQ--RRrVTLAELIDQIEA---IAVEIEK------S-----EQKPKRVKR 153 Synechocystis s...
O33208       111 VRDLLFARLLqyraFKHVAEMFAELEatalRSypRAvSLEDGFVGLLPE---VMLGVDA------HrfaeiAAIALTPRP 181 Mycobacterium t...
WP_010908297  99 GRDLLFARLLqyraFKRVAQIFAELEatalRSypHAvFLEERFASLLPE---VMIGVDA------DrfaeiAAFTFTPRP 169 Mycobacterium l...
P35154        93 PREELIEKLIeyrkYKDAAKDLKEREeerqKSftKPpSDLSEYAKEVKQ---SEQKLSV------TvydmiGAFQKVLKR 163 Bacillus subtil...
P75478       328 WraqflANkNI--------SIQelSIEQVQAEILAtikqFGyhSVSLKRVLLKV--------------N-------HHIS 378 Mycoplasma pneu...
P74212       154 A-----RP-QSrrealqiiTEL--AHQENLTELASqleqFL--QTRLPEILPDLphrswvdldtllhcWhhhldpdKLPD 223 Synechocystis s...
O33208       182 AptvatEHl----------HELmvSVPEQAEHLLA----ML--KARGSgqwasf-----------------selvadCTA 228 Mycobacterium t...
WP_010908297 170 VpivatGHl----------HELkiSVPEQAKRLLA----ML--EARGNgqwtsf-----------------selvadCRE 216 Mycobacterium l...
P35154       164 KkinrpMEtTItrq--------diPIEARMNEIV-----------------HSLksrgtrin---------fmdlfpyEQ 209 Bacillus subtil...
P75478       379 LMYFITAFVALLVLINNQIIDIEQTSFDDELYICLL 414 Mycoplasma pneumoniae M129
P74212       224 KKDKVGVFWALLLLSSQSKVSLAQEEFYQDLQVQII 259 Synechocystis sp. PCC 6803
O33208       229 PIEIVGRFLALLELYRTRAVAFEQSEPLGALQVSWT 264 Mycobacterium tuberculosis
WP_010908297 217 PIEVVGCFLALLELYRTRAIAFEQAEPLGVLQVSWa 252 Mycobacterium leprae
P35154       210 KEHLVVTFLAVLELMKNQLVLIEQEHNFSDIYITGS 245 Bacillus subtilis subsp. subtilis str. 168
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