4XM0,1Q74


Conserved Protein Domain Family
PIG-L

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pfam02585: PIG-L 
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GlcNAc-PI de-N-acetylase
Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.
Statistics
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PSSM-Id: 396922
Aligned: 69 rows
Threshold Bit Score: 53.0771
Threshold Setting Gi: 81718063
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4XM0_D            36 CIEPHPDDCAIGXGGTIKKLSDEGVEVIYICX--TD----GYXGTTDEKLSGH---------------ELALI----RRR 90  Pyrococcus ...
XP_001704790     260 LFSPHPDDDVIAAGLGLQHLNTPEIILHIAYC--VA----GYNSVGDMYLEHVpedp--------ldlCIEKTr--vREA 323 Giardia lam...
WP_012068564     139 IIAPHADDAELAAYGLYSDFAD---QVWITTI--NA----G----QNLQSLDRqyisgldetisdatqRKAQI----RAW 201 Marinomonas...
Q2J7M0             7 LVSPHPDDLAWSVGATVATLAGAGHDLHAVTVfgRSryapGSAAHGDAA-------------------SVTAL----RTA 63  Frankia cas...
Q7N992             5 FLSPHLDDAALSAGGLIHKLVSENQKVIILTF--FT-----EYDKDLTSHYSHsahn-------dniySFIKLy--sKRA 68  Photorhabdu...
Q8CZ99            11 FLSPHLDDAIFSCGDYISKLTSEGEIVLVITI--FS----GYPLSQQLQPSAKqfh---------klcNLGKYpieeRKK 75  Streptococc...
jgi:Haur_0082     11 CLSPHFDDAALSLGGALAGWHAAGERCLIVTI--CSappsGELNQFAAYLHERwg------------aASDPIa--iRRA 74  Herpetosiph...
Q2IPR0            65 VIAAHPDDETIGAASLLLRHRA-----AVVHV--TD----GAPRDPALRASGPart----------rdDHARL----RRD 119 Anaeromyxob...
jgi:Acid345_2086  13 VLVAHPDDESISCGALLQRVREP----IVVYA--TD----GGPQDEYFWGRYGsr------------eKYVAI----RRA 66  Candidatus ...
Q2WAA6             7 VLAPHPDDEVVGFSALIGRARETGTRIAILWL--TD----GIPAAELLWPWQRg-------------rRTLRVa--tRTA 65  Magnetospir...
4XM0_D            91 EEEES-A-KLL-GV--------RKIYWLN------YRDTELPY------------------------------------- 116 Pyrococcus ...
XP_001704790     324 EARSA-L-ELL-GVp------tNHIHFLR------LPFYNRNYr------------------------------------ 352 Giardia lam...
WP_012068564     202 NSMTT---PLLaGVk------fERLSSLG------YFNLTKESlyqtpkepqsdkafpaltpqisrtfntlklpndeqni 266 Marinomonas...
Q2J7M0            64 EDAAW-AdRHA-GA---------ALVSLR------LPDASLRGytddtemg------------------------aaadp 102 Frankia cas...
Q7N992            69 NEDIAfC-NKL-SVipihgkilDCIYRTDqygepmYKNSAMIYtgqih-----------------------------ksd 117 Photorhabdu...
Q8CZ99            76 EDRLA-C-ERL-QC---------DFRHLS------YYECLYRKdrngnflyr----------------------hiysel 115 Streptococc...
jgi:Haur_0082     75 EDQAA-A-NRL-GA---------DLLFLE------QHDAIYRHagydsaaaif--------------------gtpiadd 116 Herpetosiph...
Q2IPR0           120 EALAAlGeAGL-RA--------SDVIGLG------VVDQEASEa------------------------------------ 148 Anaeromyxob...
jgi:Acid345_2086  67 EAHDA-C-AAV-GV--------SEVLWLAddagcqFQDQRLFRn------------------------------------ 99  Candidatus ...
Q2WAA6            66 EAHAA-A-KLL-GA--------EAIGPLP------IPTRRLKDd------------------------------------ 92  Magnetospir...
4XM0_D           117 --SREVRKD-----LVKIIRKE--KPDG-VFAPDPWLPyeSHPDH-RRTGFLAI 159 Pyrococcus furiosus DSM 3638
XP_001704790     353 --SKRTYDQsdiriVMDIIAEV--KPNH-IFMAGDLAD--PHQTH-EVCYNIIK 398 Giardia lamblia ATCC 50803
WP_012068564     267 ssGQLLIED-----LTSLLEQI--KPST-VLVTEPEID--PHPEHiTSAY-ALA 309 Marinomonas sp. MWYL1
Q2J7M0           103 glVRRVADG-----LAALAAAV--RPRF-LLAPMAVGG---HVDH-EVVRRAVD 144 Frankia casuarinae
Q7N992           118 daSDMAQEL-----IDKILLNY--QPDY-IYAPLGIGR---HVDH-IIINNLVP 159 Photorhabdus laumondii subsp. laumondii
Q8CZ99           116 knEDTLKND-----IIKELLMHldDKCV-VYCPLSLGD---HVDH-VFVNSIGR 159 Streptococcus pneumoniae R6
jgi:Haur_0082    117 llWASLTTQ-----LQALVQQY---PDAiWYAPLAVGN---HVDH-QITHGVAA 158 Herpetosiphon aurantiacus DSM 785
Q2IPR0           149 --IDTVARE-----LAALLRSL--RPRL-VVTHAFEGG---HPDH-DATALAGR 188 Anaeromyxobacter dehalogenans 2CP-C
jgi:Acid345_2086 100 --LPAAADA-----LRKLVRQH--TPDV-ILTLAYEGG---HPDH-DSCNFLGR 139 Candidatus Koribacter versatilis Elli...
Q2WAA6            93 --FAIARQA-----VADALLRL--RPAS-MWVPAYEGG---HQDH-DVASFLAA 132 Magnetospirillum magneticum AMB-1
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