7CLV,7CGP


Conserved Protein Domain Family
Tim17
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pfam02466: Tim17 
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Tim17/Tim22/Tim23/Pmp24 family
The pre-protein translocase of the mitochondrial outer membrane (Tom) allows the import of pre-proteins from the cytoplasm. Tom forms a complex with a number of proteins, including Tim17. Tim17 and Tim23 are thought to form the translocation channel of the inner membrane. This family includes Tim17, Tim22 and Tim23. This family also includes Pmp24 a peroxisomal protein. The involvement of this domain in the targeting of PMP24 remains to be proved. PMP24 was known as Pmp27 in.
Links
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Statistics
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PSSM-Id: 426787
Aligned: 390 rows
Threshold Bit Score: 39.074
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7CLV_A        98 CYGTgavyLLGLGIGGFSGMMQGLQNIPPnSPGKLQ--------LNTVLNHITKRGPFLGNNAGILALSYNIINSTIDA- 168
XP_011271689  13 AYRE----LFQIIKSMRNGAVYGGRLRFA-HSLVIQllfrrtvpLDKRLKLVFKQSKDHGLILASFALVYKVLMIALKQi 87  Wickerhamomyces...
EEQ37040     190 AYRP----ILEALRSSRNGVVYGGKIRFS--HALVInllyrsgpMGPRLKQVLKATKEHSLVLAAFAIVYKTVLNILRQe 263 Clavispora lusi...
Q6BNB7         8 LYRP----LLEVLRSSRNGIVYGGKIRFS--HALVInllyrsgpLKPRLQQVLKATKNHAEVLAGFAIIYKFAVNVLVSe 81  Debaryomyces ha...
XP_006685249   8 LYRP----LLEVARTARNGVVYGGKIRFS--HALVInllyrsgsLRPRMIEVLKATKNHAEVLASFAVIYKMVLGVLVNe 81  Yamadazyma tenu...
XP_001485061   8 LYRP----LLEALRSARNGVVYGGKLRFS--HALVInllyrlgpLKPRLTQVLQATKSHAEVLAAFATIYQLAVKVLLHd 81  Meyerozyma guil...
CCE86625       8 LYRP----VLEAIRSSRNGIVYGGKLRFS--HALVMnilyrsgpPGPRLKSVLRATKDHAEVLAAFAFLYKVIVSVLRHe 81  Millerozyma far...
CCE45396       8 LYRP----LLEIIRSARNGVVYGGKLRFS--HALVInllyrsgpLGPRMKSVLEASKDHAEVLASFAIIYKLAVKILQSd 81  Candida parapsi...
EMG47697       8 LYRP----LFEILKSARNGIVYGGKLRFS--HALVInllyrsgpMLPRLKSVLEATKNHAEVLAAFAIIYKTCILILRQd 81  Candida maltosa...
Q38FX7       115 KYKI----LFDALKSFRNGFVYGARIRAP--HALVLnlvwssapYSVIARRVFDATRQHALRLGATAFTFSLLRSLMALv 188 Trypanosoma brucei

7CLV_A       169 ---LrGKHDTAGSIGAGALTGAL-FkSskG----LKPMGYSSAMVAA 207
XP_011271689  88 --nG-GAP--INEFISGFISAMLvY-G--NrttvFNHSIAHQITLYC 126 Wickerhamomyces ciferrii
EEQ37040     264 kllG-S-KQGFSKLIAGAVGGWIvY-S--QhfsaFNPGITHQITLYC 305 Clavispora lusitaniae ATCC 42720
Q6BNB7        82 kimG-TDKLGLVKFLAGCFGSWVvY-S--QhfnyFNPGITHQVTLYC 124 Debaryomyces hansenii
XP_006685249  82 qvlG-SNSKALSKFVAGCFGSWIvY-S--QhfgyFHPGITHQITLYC 124 Yamadazyma tenuis ATCC 10573
XP_001485061  82 qvlG-G-SKGLVKFLAGSFGAWIvY-S--QhfpyFHPGITHQITLYC 123 Meyerozyma guilliermondii ATCC 6260
CCE86625      82 klmG-PRRLALIKFIAGSFSSWIvY-S--QhfnvFHPGITHQVTLYC 124 Millerozyma farinosa CBS 7064
CCE45396      82 aflG-PKNTQLPKFIAGCLGSWIvY-S--GhfnlFHGGITHQITLYC 124 Candida parapsilosis
EMG47697      82 nflG-EKNIGLIKFISGCFGSWIvY-S--QhfpiFHSGITHQITLYC 124 Candida maltosa Xu316
Q38FX7       189 ----eGRQRPWHSVVAGFIIGCLyWg--------EQGAVTVQMSMYI 223 Trypanosoma brucei
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