3EQ5


Conserved Protein Domain Family
Ski_Sno
?
pfam02437: Ski_Sno 
Click on image for an interactive view with Cn3D
SKI/SNO/DAC family
This family contains a presumed domain that is about 100 amino acids long. All members of this family contain a conserved CLPQ motif. The c-ski proto-oncogene has been shown to influence proliferation, morphological transformation and myogenic differentiation. Sno, a Ski proto-oncogene homolog, is expressed in two isoforms and plays a role in the response to proliferation stimuli. Dachshund also contains this domain. It is involved in various aspects of development.
Links
?
Statistics
?
PSSM-Id: 426774
Aligned: 27 rows
Threshold Bit Score: 131.25
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
3EQ5_A        22 SMPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREF--TLQQINTVCDELYIYCSRCTSDQLHILKVLGILP 99  human
XP_011605191  81 E-NIPQNNECKMVELRGAKVASFTVDGCELICLPQAFDLFLKHLvgGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQ 159 torafugu
EKC27827      58 A-CNPDNNVCKVITYRGEKVAAFTVNGIELICLPQAFELFLKHLvgGLHTVYTKLKRLDITPVVCNVEQVRILRGLGAIQ 136 Pacific oyster
CAP20864      91 T------LTVKLVPFRGHSVAAFDIDGKEMICLPQVYEIFLKNMvgGLHTVYTKLKRLYIHPVVCNVEQVRALRSLGAIQ 164 Caenorhabditis ...
XP_011666704  32 S-NDPANNECKLIEYRGAKIASFNINGDCMICLPQAFELFLKHLvgGLHTVYTKLKRLSITPVVCNVEQVRILRGLGAIQ 110 purple sea urchin
KOB66933      85 STSDPSANECKLVDYRGQKVAAFIIQGDTMLCLPQAFELFLKHLvgGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQ 164 winter moth
XP_002407755  97 P-SDASATDCRLIDYRGAKVAAFYVAGEYLLCLPQAFELFLKHLvgGLHTVYTKLKRLDITPIVCNVEQVRILRGLGAIQ 175 black-legged tick
EKC29506      19 gsyvarpNQVSTVMLHGVPIVSLYIDGKERLCLAQISNTLLKQY--SYNEIHNRRVALGITCVQCTPVQLEILRRAGAMP 96  Pacific oyster
XP_003242376  39 KVLFCLSNQVGTVILYGVPIVSLQMDNQERLCLAQISNTLLHRF--SYNEIHNRRVALGITCVQCTPVQLEMLRRAGAMP 116 pea aphid
EFN61391     113 Q------NQVGTVSLYGIHIVSLVIEGQERLCLAQISNTLLKQF--SYNEIHNRRVALGITCVQCTPVQLEILRRAGAMP 184 Florida carpent...

3EQ5_A       100 FNAPSCGLITLTDAQRLCNALL 121 human
XP_011605191 160 PGVNRCKLISRKDFETLYNDCT 181 torafugu
EKC27827     137 PGVNRCKLISCKEFDVLYDDCT 158 Pacific oyster
CAP20864     165 PGVNRCKLLETRDFEKLYDDCT 186 Caenorhabditis briggsae
XP_011666704 111 PGVNRCKLLTRKQFDILYEDCT 132 purple sea urchin
KOB66933     165 PGVNRCKLLSCKDFDVLYRDCT 186 winter moth
XP_002407755 176 PGVNRCKLLSCKDFDALYKDCT 197 black-legged tick
EKC29506      97 ISSRRCGMITMREAERLVKSFL 118 Pacific oyster
XP_003242376 117 VSSRRCGMITRREAERLCNSFL 138 pea aphid
EFN61391     185 VSSRRCGMITRREAERLCKSFL 206 Florida carpenter ant
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap