4IFX,1VRM


Conserved Protein Domain Family
ApbE

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pfam02424: ApbE 
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ApbE family
This prokaryotic family of lipoproteins are related to ApbE from Salmonella typhimurium. ApbE is involved in thiamine synthesis. It acts as an FAD:protein FMN-transferase, catalyzing the attachment of an FMN residue to a threonine residue of a protein via a phosphoester bond in such bacterial flavoproteins.
Statistics
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PSSM-Id: 426767
Aligned: 688 rows
Threshold Bit Score: 90.9626
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4IFX_A         18 GTLCRVRvyskr------paaeVHaalEEVfTLLQQQEMVLSANRD---DSALAALNAQags---apvVVD-R---SLYA 81  Treponema pall...
CCY67616       37 dTASSITaads-------sqqaFDahyETVyNELKTYSELFDIYNSygdLVNLKYINENaak---apvKAD-K---KIID 102 Clostridium sp...
CDC32264       37 dTASSITaydt-------sqaeFDkkyNKLyGEIKGYSELYDIYNDydnIVNLKYINDNayk---kpvKVD-K---RIIE 102 Eubacterium sp...
CCX49286       36 DTVTELTiyak-------deaaAAdaaKAAhERLIYLNRLYDIYNEyddAVSLMAVNASaan---apvSVS-D---ETMA 101 Clostridium sp...
CDA34894       44 fdtSITFqadc-------tdeeFAkytKIVeNTFKENNKRFDQYHAyskINNIYTINHEaan---hpiEVD-Q---TTMK 109 Firmicutes bac...
Q8EH13         51 GTSITIDiyeadkdkaylalchAL---NVV-QEYHYLASNFSTYPG---YTNIQTINNnpe----klhHID-A---KLTE 115 Shewanella one...
jgi:Fbal_2899  53 GTSIAIQvydagegdakqalcdSL---ATI-KRLHQQGSDYQTYDG---VVNIRSINNapt----evhKID-P---ELTE 117 Ferrimonas bal...
ADC90773       51 dTVVTLSangyqteefeaacqdLH---KEM-QRYHHLLDIYHTYDG---VTNLKSINDAaaegsanhiKVD-P---ELMH 119 Mageeibacillus...
CDF01271       40 DTLCSIKa--------------EKksvSELtDVLNKFNIAFDCCSE---NGEAYQLNKNk--------SMIcSe--nLAD 92  Ruminococcus s...
CDE30076       49 DTICTITa--------------PEslqEPLaETMRQLDDQLDCYDA---ESVVSRCNQSg--------T---SqdtMLYD 100 Ruminococcus s...
4IFX_A         82 LLERALFFAEKSGGAFNPALGAVVklwnigfdraavpdpdalkealtrcd----frqvhlragvsvgaphtvqlaqagmq 157 Treponema pall...
CCY67616      103 LLLWGKEAYEISGGRVNIAMGAVLsiwhdareysianpdsaylpdmeslke--kfahtdindlvideeastvyfadakms 180 Clostridium sp...
CDC32264      103 LLTYGKKAYKITNGYVDIAMGSVLsiwhdyrekgeslppksmltkase--------htdinnliidkenstiffndkelk 174 Eubacterium sp...
CCX49286      102 LLKFAKEAYKLTGGRVNAAMGSVLsiwhdyreagledeanaqlppmellkq--aaehtdinsivldeangtvfftdsmvr 179 Clostridium sp...
CDA34894      110 CIKDAIKINQVCS-KFDISYGSVMniwhdyreqgmtlnekgksgnlpsqeel-navsqhtgmdkiqiqgntifltdsqcm 187 Firmicutes bac...
Q8EH13        116 ILTTSIEWHGITQGRFNIALAPVLevwrsyrkrcqqggacelpsdtelan----aakhidikqitldannntiqmkagmk 191 Shewanella one...
jgi:Fbal_2899 118 LIQAGIDWHRISKGYFNIAVGPVVqqwrqkrnacaepeaadngcslpspqaienaskytdiskinldvdantvtlgegms 197 Ferrimonas bal...
ADC90773      120 FLKESKKIYNITSGATNIALGSVIdlwhreriaaldhpdkaklpdeaslka--agkhiniddlvldtennevsvkdrnlr 197 Mageeibacillus...
CDF01271       93 LIKKSKELSQKYGDEVLISSGALTllwkdakknnilpeetqiktlink--------tgdnlieitsedgqskidlkqnce 164 Ruminococcus s...
CDE30076      101 LVTQVQTAQQQDGVKVDVTIGALTalwgittdhpkvptaaqrqqal------------atvspehvttkdgtvslsggaq 168 Ruminococcus s...
4IFX_A        158 LDLGAIAKGFLADKIVQLLTAh----aLDSALVDLGGNIFALGlkygdvrsaaaqrleWNVGIRDP------HGTGQkp- 226 Treponema pall...
CCY67616      181 LDVGAVAKGYICEKISGFITEnk---iWQSALINLGGNVKTLGfknad------gktpYNIGIEDP--------NGGyl- 242 Clostridium sp...
CDC32264      175 LDVGAITKGFVCNKIYEYITKnn---vWQSAVISLGGNIITIGnkpd--------kndFVIGIENP--------NSNey- 234 Eubacterium sp...
CCX49286      180 LDVGAIAKGFAGQIVTDELNAridtgeISAALISLGGNVCAAGtkpn--------geaWQIAVQDP------RGSDNaa- 244 Clostridium sp...
CDA34894      188 LDLGGIAKGYTAQLTKEKLNKa----gLHNGFINAGGNVVLIGkksd--------gsnWNIGVQNP-------DSSDsl- 247 Firmicutes bac...
Q8EH13        192 LDLGGIAKGWMVEKVYDQLKAd----nINAFMINAGGNIRHFGthpd--------grqFITAIENPlirkyqLEHKDfne 259 Shewanella one...
jgi:Fbal_2899 198 LDLGGIAKGWMAEKVKDQLVAa----gMRSFVINAGGNIRHWGrhpq--------graFVTAIEDPvckkydFQPSQcqq 265 Ferrimonas bal...
ADC90773      198 LDGGAIAKGYIADRLADYAISk----hYNHFLLNIGGNIKAVGskda-------agtpWSVAIQNPekeap--------- 257 Mageeibacillus...
CDF01271      165 IDTGAFAKGYSLDFCKSVLDRn----nTDYAVISMTSSILLYGekpd--------ntdFKVQIRDPngkg---------- 222 Ruminococcus s...
CDE30076      169 LDFGAVAKGYAMDQAAAVLNQs----dASYAIVSMESSMVLYGakpn--------gkpFVISVRDPdgeg---------- 226 Ruminococcus s...
4IFX_A        227 -------alVVSVRd-cS-VVTSGAYERFFeR-DGVRYHHIIDPVTgfpahtDVDSVSIFA-PRsTDADALATACFVlgY 295 Treponema pall...
CCY67616      243 --------aVVNAAngvS-VVTSGDYQRYYtV-NGEKYCHIISPDTlmp-aqGIRSVSIIS-EDsALADVLSTTLFQmqP 310 Clostridium sp...
CDC32264      235 -------ldKIYADdntS-VVTSGSYQRYYtV-DGKDYCHIIDKNTlyp-anYFKSVTVIS-SDsALADTLSTALFCm-- 301 Eubacterium sp...
CCX49286      245 -------taSIASGy----VVTSGDYQRYYtV-NGVRYNHIIDPDTlms-adKHASVTVIS-SDgALADALSTALFImdT 310 Clostridium sp...
CDA34894      248 -------lnIEVDQtnqA-IVTSGDYQRYYnV-NGTRYSHIIDPDTlmp-akQCRSVTVLT-KNsTKADGLSTALFSlnF 316 Firmicutes bac...
Q8EH13        260 inngdiyheIIQGEd-iT-IVSSGNYLNYYav-nGQEYHHIIDPTTlyp-kkQGISVSVIMkNKpILADVISTSLFLlpM 335 Shewanella one...
jgi:Fbal_2899 266 le--gqfheIVAGEn-lT-IVSSGNYLKYYrv-gDKEYHHIINPNTgyp-ktEGVSVSVVMnEQhIYADVLSTTLFLmpM 339 Ferrimonas bal...
ADC90773      258 ----npyllVLNLVd-tT-LVTSGIYERFYif-hGKCYHHIIDPATlfp-sdrFKSVSVFThSS-TLADGLTTGLFNmdL 328 Mageeibacillus...
CDF01271      223 ------tigTVE-Tp-aCfLSTSGGYERFFti-dGKDYCHIIDLNTgcpsesDLTSVTVFA-DSgILTDYMSTKIFIegT 292 Ruminococcus s...
CDE30076      227 ------ilgTIE-Tp-aCfLSTSGGYERYFtaedGTAYEHILDPQTgmpvetDLKTVTVLC-DSgLRSDLLSTEIYMegT 297 Ruminococcus s...
4IFX_A        296 EKSCALLREf----pGVDAL 311 Treponema pallidum subsp. pallidum str. Nichols
CCY67616      311 QDALAFLKTve---gCEAVI 327 Clostridium sp. CAG:678
CDC32264      302 -DLNTGRKLaek-ynIQAIW 319 Eubacterium sp. CAG:251
CCX49286      311 GEGRALIDSia---dAEALW 327 Clostridium sp. CAG:226
CDA34894      317 EDG----YAlakkekVQAIW 332 Firmicutes bacterium CAG:536
Q8EH13        336 PEAQDLIKRig---dIEAVW 352 Shewanella oneidensis
jgi:Fbal_2899 340 KEAMDMAESip---yLEAVW 356 Ferrimonas balearica DSM 9799
ADC90773      329 AAGQSLVAKld---dVEAVW 345 Mageeibacillus indolicus UPII9-5
CDF01271      293 QN----IENhlnaadykiaa 308 Ruminococcus sp. CAG:624
CDE30076      298 AG----LERhlqatdyqvla 313 Ruminococcus sp. CAG:403
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