1GU6,6P73,3BNF,6V0A


Conserved Protein Domain Family
Cytochrom_C552
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pfam02335: Cytochrom_C552 
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Cytochrome c552
Cytochrome c552 (cytochrome c nitrite reductase) is a crucial enzyme in the nitrogen cycle catalyzing the reduction of nitrite to ammonia. The crystal structure of cytochrome c552 reveals it to be a dimer, with with 10 close-packed type c haem groups.
Links
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Statistics
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PSSM-Id: 426726
Aligned: 24 rows
Threshold Bit Score: 528.077
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1GU6_C            17 ETFAPQHPDQYLSWKATSE-QS----------------------ERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVT 73  Escherichia...
Q0P8Q2            57 EKWGKVFPEQLKMYLTVEK-EEpkate-------------fggnLAYSKLIRFPQLTILWAGYPFSLDFNEERGHFWVQV 122 Campylobact...
Q24UN1            47 ETWGKVYPDQYASQNKQKE-MTkgnsk-------------yggsLPESHLEKYPIEKRLFAGYGFSEDYNDERGHVYALE 112 Desulfitoba...
jgi:Anae109_0955  60 AVWGKNFPVEYDLYKKTTD-MVrtkyggseaiprspteqdprkvTSQSKTDADPRLKTMWAGYAFAADFREERGHAYTLD 138 Anaeromyxob...
Q39YY5            46 AVWGKAYPTEYEMWKKTEEpEPpgkskyk--------rgfdadhVTYDKLSEFPYMALLFNGWGFGIAYNEPRGHANMVR 117 Geobacter m...
6V0A_C            43 AVWGKNYPEEYQTWKDTAL-PTpegksky--------kkgndggKVYDKLSEYPFIALLFNGWGFGIEYNEPRGHVYMMK 113 Geobacter l...
ACH39932          43 AKWGEVYPEQYRLWQQTAE-PTpagksryk-------kgwdvgeELPDKLDEYPFLALLYNGWAFGSEYREPRGHRYMVQ 114 Geobacter b...
ACH39083          54 AHWGRLYPVHYQQWKLTSE-PTpaglskyk-------rgydvgeERRDKLDEYPFLALLYSGWGFGAEYNEPRGHYHMVQ 125 Geobacter b...
WP_012468300      45 AEWGKVYPLQYKLWQQTGE-PTpagkskyk-------kgydvdeDRRDKLDEYPFLALLYNGWGFGSEYREPRGHFFMVQ 116 Geobacter l...
Q747W1            49 AEWGKAYPVHYDLWKKTEEpTVagksryk--------kgydddgVFYDKLDEFPFLALLYNGWGFGVEYKEPRGHAHMVR 120 Geobacter s...

1GU6_C            74 DVRETLRTGAPKNAEDG-----PLPMACWSCKSPDVARLIQKDGE-------DGYFHGKWARGGPEIV-------NN--- 131 Escherichia...
Q0P8Q2           123 DQMKTARNNKDFLNAHGlaafkGQPAACMNCHSGWTPWLIKNVAKgd----fTAFNSTNYWTMIKNIPavdgiveNSpeh 198 Campylobact...
Q24UN1           113 DVTTTLRVNE------------KTISSCWNCKSPQVPGLIEQMGD--------DFWSTPFLQLKDQIT-------MP--- 162 Desulfitoba...
jgi:Anae109_0955 139 DQIFTQRQVVA-----------KQPGTCGQCHASVYV-PMKKLGDgdifkgfEALNKMPYSEAKQHFK-------HP--- 196 Anaeromyxob...
Q39YY5           118 DQLEIDSARL------------KSGGVCLTCKTPYAPKLEKEMGI--------DYFKTPFKDVLAKIPe-----kHKtl- 171 Geobacter m...
6V0A_C           114 DQKEIDPSRL------------KGGGACLTCKTPYAPQLAQKQGV--------TYFSQSYADAVNQIP-------KEhqe 166 Geobacter l...
ACH39932         115 DQLEVDPGRY------------KAGGSCLTCKTPYAPILQGQMGK--------DYFAKPYQEVRAKIP-------KEhqe 167 Geobacter b...
ACH39083         126 DQLEVDPGRL------------KAGGACLTCKTPYAPKLQKEMGR--------AYFATPYKEVLARLP-------KQnqt 178 Geobacter b...
WP_012468300     117 DQLEVDPGRV------------KAGGSCLTCKTPYAPILEKQMGK--------AYFSTPYKEVLAKLP-------KDqqt 169 Geobacter l...
Q747W1           121 DQFEVDPGRV------------KAGGSCLTCKTPYAPALQQRLGK--------DYFSKPYKEVHAQIPk-----eHQml- 174 Geobacter s...

1GU6_C           132 ----------LGCADCHNTASPEfakgkpeLTLSRP-YAARAMEAIGK-------P-FE--KAGRFDQQSMVCGQCHVEY 190 Escherichia...
Q0P8Q2           199 agphggkrmgVTCADCHNPNDMS-------LRLTRP-AAINALVSRGYe-----kDpVQgvKATREEMRTLVCSQCHVEY 265 Campylobact...
Q24UN1           163 ----------IACADCHDPETMN-------LRITRV-TLLNALKERGI-------DpNQ---LSRQEMRTMVCAQCHVEY 214 Desulfitoba...
jgi:Anae109_0955 197 ----------VACIDCHDSKTMA-------LRVTRP-GFMEGIRAFKAsqgienyDpNT--MATRQEMRAYVCGQCHVEY 256 Anaeromyxob...
Q39YY5           172 ---------gVACIDCHDNKDMS-------LRISRGfTLGEALKKLGV-------DqAK---LSRQEMRSLVCAQCHVTY 225 Geobacter m...
6V0A_C           167 --------mgVACIDCHNNKDMG-------LKISRGfTLVKALDKMGV-------DqTK---LTNQDKRSLVCAQCHVTY 221 Geobacter l...
ACH39932         168 --------lgVSCIDCHDNRDASs------LKISRGfTLGKGLKALGV-------DqAH---LTRQDMRTLVCAQCHVTY 223 Geobacter b...
ACH39083         179 --------lgVACIDCHDNRGME-------LRISREfTLGKALRKIGV-------DpAK---LTREQKRTLVCAQCHVTY 233 Geobacter b...
WP_012468300     170 --------lgVACIDCHDNRGMA-------LKISRGfTLGKGLKNIGL-------DeTK---LAKAEMRTLVCAQCHVSY 224 Geobacter l...
Q747W1           175 ---------gVACIDCHNNNDLS-------LKVSRGfTLGKALEKLGV-------DqEK---LSTQDKRTLVCAQCHVTY 228 Geobacter s...

1GU6_C           191 YFDGK---------------------------------------------NKAVKFPWDDGM-----KVENMEQYYDKIA 220 Escherichia...
Q0P8Q2           266 YFKPTgekvkvmgetivddsskkwwngtqknydeyefwrdgnkvkeietdGIVLTFPWSEWKkgqpfRIEMLDDYYDKVR 345 Campylobact...
Q24UN1           215 YFEPE---------------------------------------------TKRVTYPWKYGL-----TANDAEKYYEEIN 244 Desulfitoba...
jgi:Anae109_0955 257 YFKGA---------------------------------------------EKRLTFPWSKGM-----KADQIAEYYDEVG 286 Anaeromyxob...
Q39YY5           226 NIPKDad-----------------------------------------kkSIGVYFPWQGSKmg-niSVENIIKQIRSDA 263 Geobacter m...
6V0A_C           222 TIPKDan-----------------------------------------mkSQDVFFPWDESKwg-kiSIENIIKKMRSDK 259 Geobacter l...
ACH39932         224 SIPKDaa-----------------------------------------vkSTDVFFPWQGSAwg-diSIENIIKQLRNNP 261 Geobacter b...
ACH39083         234 MIPKDkd-----------------------------------------mhSTDVVFPWAGSReg-giPIENIIKDIKSSP 271 Geobacter b...
WP_012468300     225 IITKDke-----------------------------------------mhSTDVVFPWKGSKag-yiTIENIIAQIKSSP 262 Geobacter l...
Q747W1           229 SIPKDen-----------------------------------------mkSTDVFFPWDGSSyg-giTIENIIAKLRSNP 266 Geobacter s...

1GU6_C           221 ---FSDWTNSLSKTPMLKAQHPEYETWT-AGIHGKNNVTCIDCHMPKVQnAEGKLYTDHKIGNPF-DNFAQTCANCHTQD 295 Escherichia...
Q0P8Q2           346 gvfGADFTHKLTGAQIIKIQHPESELYS-GGVHAANGVSCVDCHMPYVR-EGAKKVTQHNITSPL-RDINSACKSCHKQS 422 Campylobact...
Q24UN1           245 ---FKDWNHAETGAPMLKAQHPDYELFS-TGVHAANGVACADCHMPYVK-EGTSKISSHHLQSPL-NSISESCQTCHRQS 318 Desulfitoba...
jgi:Anae109_0955 287 ---FRDWTHKESGAPALKAQHPEFEMWN-QGIHARSGVACADCHMPYMR-VGGTKVSDHWVRSPV-LNLNRACQGCHKWP 360 Anaeromyxob...
Q39YY5           264 s--VGEWTQTVTGFKLGFIRHPEYELFSnNSVHWKAGAACTDCHMPYTR-VGAFKVSDHRVMSPLkNDM-KACIQCHTEK 339 Geobacter m...
6V0A_C           260 s--YGEWTQAVTGFKMAYIRHPEFEMYSnQSVHWMAGVSCADCHMPYTK-VGSKKISDHRIMSPLkNDF-KGCKQCHSES 335 Geobacter l...
ACH39932         262 p--SGEWTQSVTGFKLAFIRHPEFELFSrNSPHWQAGASCADCHMPSAE-VAGRKVSDHRVMSPL-KNDLKACKQCHEET 337 Geobacter b...
ACH39083         272 s--HLEWTQAVTGFKLAFLRHPEYEFYSnNSPHWSAGVTCADCHMPMMT-VSHESLTDHRIMSPL-KGEMTQCAGCHEEK 347 Geobacter b...
WP_012468300     263 a--NMEWTQSVTGFKMGFIRHPEYELFSnNSPHWTNGVSCADCHMPTVT-EDGQKISDHRIMSPL-KNDLIACAACHSEK 338 Geobacter l...
Q747W1           267 a--NREWTQGVTGFKLAFIRHPEFELFSnNSVHWQAGVACSDCHMPYTK-VGTRKVSDHRVMSPLkNDL-KACQQCHAES 342 Geobacter s...

1GU6_C           296 KAALQKVVAERKQSINDLKIKVEDQLVHAHFEA----------------KAAl-DAGATEAEMK-----PIQDDIRHAQW 353 Escherichia...
Q0P8Q2           423 EDYLKAQVLDIQNSVAHDQRTAEYAIVSLIMDTkklrdelgnmekfqsdGKA--DAKKISEELK-----EVLELHRKAQM 495 Campylobact...
Q24UN1           319 EEYLKNQVIATQDKVFATRTVLENALADAMDAI----------------KTAdkNANAKADAMS-----KARDLHRKAQW 377 Desulfitoba...
jgi:Anae109_0955 361 EEELKARVEAIQDKHMELREQAFDALVALIGDI----------------KAAk-EAGKGDADLE-----KARFLQRRAQF 418 Anaeromyxob...
Q39YY5           340 PEWLRDQVIAIQDRTVSLMLRSGYATATVAKLF----------------EKAh-AAQAQGKQIDkalydRAKDLYEEAFY 402 Geobacter m...
6V0A_C           336 SEWLKNQVITIQDRAASQYIRSGYALATVAKLF----------------EMTh-KQQAAGKQIDqkmydQAKFYYEEGFY 398 Geobacter l...
ACH39932         338 PDALRDKVFAIQDRVMSQYIRAGYATASAAKLF----------------EIAh-KAGAAGRTLEpalyaQAKDHYEEAFY 400 Geobacter b...
ACH39083         348 APELRAKVIAMQDRFIGSYLKTGYAVAADAKLF----------------EMAn-KAKAAGKQIDnevygIARENYEQAFY 410 Geobacter b...
WP_012468300     339 PQELRDKIIAIQDETMIVYLKAGYATATVAKLF----------------EMTn-KVEASGKKINkdlyaQSKEQYEQAFY 401 Geobacter l...
Q747W1           343 PEWLRNQVYAIQDRTMSQFIRAGYATATVAKLF----------------EMAh-KAQAEGKQIDkalydQARDHYEEAFY 405 Geobacter s...

1GU6_C           354 RWDLAIASHGIHMHAPEEGLRMLGTAMDKAADARTKLARLLATKGITH----EIQIPDISTKEKAQQAIGLNMEQIKAEK 429 Escherichia...
Q0P8Q2           496 RADFVNAENSTGFHNPREASRMLLQAVDMARMGQTKLVEIAAANGIKDfktsNLGFEDIQKFNPGELYYKVDVNNHKAGE 575 Campylobact...
Q24UN1           378 RWDYIAAENSMGFHSPNEALRVLGEGIDFARQAQLQANLAVGTAAGGAanpdAGQTPGAGTANEAAGGATPLPDNKNNDK 457 Desulfitoba...
jgi:Anae109_0955 419 LFDFVEAENSTGFHAPQEAARVLFESVDASRQGQLALRDPSFEPTVAV-----VTIPPPPPAPGAAPAVQPAAVkr---- 489 Anaeromyxob...
Q39YY5           403 RCVFIGAENSVGFHNPTEAMRVLGDATAFATKAEALLRQALAKAGVDV--------PLTVNLELNKYLDQRGEKKLTFDP 474 Geobacter m...
6V0A_C           399 RNLFFGAENSIGFHNPTEAMRILGDATMYAGKADGLLRQALTKAGVDV--------PVKIDLELSKYTNNRGAKKLMFKP 470 Geobacter l...
ACH39932         401 RVVFIGAENSAGFHNPAEASRIMTDAAGHAAKAQALLRQLLAKAGIEA--------PAQVDLELAKYLNNRGVKKLMFKP 472 Geobacter b...
ACH39083         411 RLIFVGAENSTGFHNPKEGLRILDDAARHAATADMHLRQMLAKAGERV--------PDQVDLELPKYTGNRGTKHLPFRP 482 Geobacter b...
WP_012468300     402 RLIFIGAENSNGFHNPKETMRVLNDAAKYAASADAQLRKLLTQAGEKV--------PEKIDLELSKYTNNRGVKKIMFKP 473 Geobacter l...
Q747W1           406 RVVFIGAENSIGFHNPTEALRITGDAAAHAGKAEGFLRQALAKAGVTV--------PLKVDLELAKYTNNRGVKKLMFKA 477 Geobacter s...

1GU6_C           430 QDFIKTV-IPQ-WEEQARK 446 Escherichia coli
Q0P8Q2           576 RYYADEKdVNGnPPKELLE 594 Campylobacter jejuni
Q24UN1           458 KPTDGDGsAPNdETKQTEE 476 Desulfitobacterium hafniense Y51
jgi:Anae109_0955     -------------------     Anaeromyxobacter sp. Fw109-5
Q39YY5           475 KVEIKDPyGVQvrf----- 488 Geobacter metallireducens GS-15
6V0A_C           471 EQELKDP-YGPqk------ 482 Geobacter lovleyi SZ
ACH39932         473 QHEIKDP-LAgk------- 483 Geobacter bemidjiensis Bem
ACH39083         483 EHEIKAP-Ivk-------- 492 Geobacter bemidjiensis Bem
WP_012468300     474 EHEIKSP-Evk-------- 483 Geobacter lovleyi
Q747W1           478 EHEIKDPlAAKek------ 490 Geobacter sulfurreducens
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