Conserved Protein Domain Family
SRP14

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pfam02290: SRP14 
Signal recognition particle 14kD protein
The signal recognition particle (SRP) is a multimeric protein involved in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP14 and SRP9 form a complex essential for SRP RNA binding.
Statistics
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PSSM-Id: 460524
Aligned: 123 rows
Threshold Bit Score: 58.8739
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGX49655       6 LSNDEFFTKLSDLLVS--KKDHGS-VFLTQKRlSYDPSNPpptktltrpskvtkptstkkkpssssssiftktihpqpte 82 
EFX67132       4 LENDAFLTSLTLMYQKarLHG--S-VRVTLKR--YDGRTKpv-------------------------------------- 40 
CUT99547       3 LDNDAFLSALTKMFAEskSGK--S-LFITMKR--HDGRTKpv-------------------------------------- 39 
ESO00160       1 -----FLSEMTRMFQKskLGK--P-IQLTMKK--YDGRTKpi-------------------------------------- 32 
EFO17268       4 LDNDHFLVELAKLFQKcrTST--QrITITLKH--YDGRTKpy-------------------------------------- 41 
PDM74665       4 LDNDVFIKELGKFFFNsrTGGPKN-VAVTMKR-Y---------------------------------------------- 35 
XP_001629465   4 LDNDGFLTQLTYLLQKsrTAG--S-VYITVKK--YNGQTRpk-------------------------------------- 40 
XP_009862302   4 LENDSFLTELTTLYQKcrTSG--T-VYVTMKK--YDGRTKpk-------------------------------------- 40 
Q6AZK8         4 LESEQFLTELTRLFQKcrTSG--S-VYITLKK--YDGRTKpv-------------------------------------- 40  tropical clawed...
XP_014440031   4 LESEQFPTELTRLFQKrwLLS--S-AYVTLKK--YDDQTKri-------------------------------------- 40 
EGX49655      83 adlkADLLSLLsepTASAEEETSETtTPVPILIRATNGKSNdprhngkhikLSTVVETDQLEAFFTRYAEVCKQGLTGL 161
EFX67132      41 ---pRVEAAA------NKEe------PEYSCIFRATLASKK----------ISTIVTANALSEFQAAFSSTIRSNMDGL 94 
CUT99547      40 ---pRKKGNQ------VPR---ASTsGENCCLMRVTLGSKK----------ISTLIYQRDMNRFNQAYANVIKANIDGL 96 
ESO00160      33 ---pRDGKPS------LPEa------QEHKCLIRVVLGNKK----------ISTVVCQKDINKFQLAYANVLKGNMDGL 86 
EFO17268      42 ---pRNEAQQ------SLK-------GEDLCLFRVKLGNRK----------ISTVVHAKEVNKFQLAYAGILKANMDNL 94 
PDM74665      36 ----------D---GRNKPKPDETAvVEPSVLFRAVCGNKK----------ISTVVKAKEVNNFTIIYTSLMKESMDNL 91 
XP_001629465  41 ---pRASKKH------AKL-TSVEHeGESKCLFRATNGKKK----------LSTIVNTKDVNRFQLAYANVLKANMDNL 99 
XP_009862302  41 ---pKPNNLR------SKQKPQVQApIEGLCLIRATNGKKK----------LSTVVNAKDINKFQMAYTSVLRANLDGL 100
Q6AZK8        41 ---pRKGQSD------SVEp------AENKCLLRATDGKKK----------ISTVVSSKEVNKFQMAYSNLLRANMDGL 94  tropical clawed ...
XP_014440031  41 ---rKKGTVE------GFEp------SDNKCLLKATDGKKK----------INTVMSSKEVNKFQMVYSNLLTANMDGL 94 
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