5MSJ,7DR6


Conserved Protein Domain Family
PA28_alpha

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pfam02251: PA28_alpha 
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Proteasome activator pa28 alpha subunit
PA28 activator complex (also known as 11s regulator of 20S proteasome) is a ring shaped hexameric structure of alternating alpha and beta subunits. This family represents the alpha subunit. The activator complex binds to the 20S proteasome ana simulates peptidase activity in and ATP-independent manner.
Statistics
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PSSM-Id: 426676
Aligned: 41 rows
Threshold Bit Score: 62.5624
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5MSJ_A         8 PEAQAKVDVFREDLCSKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAP--LDIPVPDP 68  house mouse
EKC40285      12 SATLQKVKEFKDNFKEEGDHLVQDVFPAKILELEELYQS--MTMSCLADIHVD--LNIPVPDP 70  Pacific oyster
XP_790819      3 NDDPREVTACKDKLHQMSENLVKVLFPQKIGELGELVESDLFKLSRMSEVVCN--INIPVPAP 63  purple sea urchin
2_pfamImport   1 VPENKELSEYKQNLFAEAEKIVKEEFPRKVIEFNSLLKSPRLSYDRLAEILPDksLNIPVPNV 63 
EFA05370      15 ESAYHEVLEYKDSLKKEAEELLLKGFPATIVKLNALLETPQFKNRKFTDVHQE--LNIPHIAR 75  red flour beetle
Q7QF52         2 EDNARKVQQYKDNLISRAETLITKEFPERIVRLNALLDTPQFSERSFTDVYQE--LNIPVPEP 62  Anopheles gambiae str. PEST
EFX88554       2 VDNASKVLQYKETVKKQAEDLINNGFPRKIVELNDLLATPLFSTKNLEEVHQD--LKVPVPSP 62  common water flea
KMZ09564       3 NDTVVKVQEYKDSLILKAEMLITKGFPENIVRLNELLATPIFNERNFEEVHQD--LNIPVLPP 63  Drosophila simulans
CDS38116       3 NDVLEELQRYKEQTKVDGETLVRTVFPKRVFEMRELLASKLFNF-EPAGVYQK--VNLPVPLT 62  Echinococcus multilocularis
XP_009028128  17 SEAETQVEELKNKTKAKGEQLIKETIPKKILELNKLLESDIFSMSRYKSVIVK--LNIPVPEV 77  Helobdella robusta
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